Thirty-four years old patient, female, husband died of AIDS (Acquired Immunodeficiency Sindrome). She's confined to Hospital Universitário João de Barros Barreto, with a positive test for AIDS, fever; 10 kg/month of weight loss, diarrhea with gummy faeces, productive cough, yellowish sputum. The therapy was initiated, symptomatic, associated to Epivir; Saquinavir and AZT. The searching exams for Alcohol Àcid Resistant Bacili and fungi in the sputum were negative. At the hemogram was shown a pancytopenia, the esophagogastroduodenunscopy showed light esophago moniliasis. During commitment presented a perforating acute abdomen chart, the abdominal radiography showed hidroair levels, pneumoperitoneum, enlarced bowels with swollen wall. She was undertaken a surgery with diagnosis hypothesis of cytomegalovirus perforation, which accordin to leterature is the most frequent cause of intestinal perforation in patients with AIDS