New Delhi metallo-beta-lactamase-1-producing Acinetobacter spp. infection: report of a survivor
Rev. Soc. Bras. Med. Trop; 49 (1), 2016
Publication year: 2016
Abstract:
New Delhi metallo-beta-lactamase-1 (NDM-1) is a bacterial enzyme that renders the bacteria resistant to a variety of beta-lactam antibiotics. A 20-year-old man was hospitalized several times for surgical treatment and complications caused by a right-sided vestibular schwannoma. Although the patient acquired several multidrug-resistant infections, this study focuses on the NDM-1-producing Acinetobacter spp. infection. As it was resistant to all antimicrobials tested, the medical team developed a 20-day regimen of 750mg/day metronidazole, 2,000,000IU/day polymyxin B, and 100mg/day tigecycline. The treatment was effective, and the patient recovered and was discharged from the hospital.
Acinetobacter/efectos de los fármacos, Acinetobacter/enzimología, Infecciones por Acinetobacter/tratamiento farmacológico, Infecciones por Acinetobacter/microbiología, Antibacterianos/farmacología, Antibacterianos/uso terapéutico, Infección Hospitalaria/tratamiento farmacológico, Infección Hospitalaria/microbiología, Farmacorresistencia Bacteriana Múltiple, Pruebas de Sensibilidad Microbiana, Resultado del Tratamiento, beta-Lactamasas