Asociación entre variables hormonales y clÃnicas y el resultado del ultrasonido ginecológico en mujeres con sÃndrome metabólico
Association among hormonal and clinical variables and the result of the gynecological ultrasound in females with metabolic syndrome
Rev. cuba. endocrinol; 19 (2), 2008
Publication year: 2008
Determinar la asociación entre el resultado de ultrasonido y los valores de progesterona, Ãndice LH/FSH, testosterona, antecedentes de infertilidad e hirsutismo en mujeres con sÃndrome metabólico. Se realizó un estudio descriptivo-transversal con 90 mujeres, entre 18 y 45 años de edad, con diagnóstico de sÃndrome metabólico.
Se les realizó:
FSH (3-5 dÃas del ciclo menstrual si menstruaba), LH (3-5 dÃas del ciclo menstrual si menstruaba), prolactina (3-5 dÃas del ciclo menstrual si menstruaba), andrógenos (testosterona total, 3-5 dÃas del ciclo menstrual si menstruaba), de lo contrario en cualquier momento y progesterona (21-23 dÃas del ciclo menstrual si menstruaba), ultrasonido ginecológico transvaginal en la fase folicular temprana si menstruaban, y si estaban en amenorrea en cualquier momento. Además se les realizó una historia clÃnica que exploraba historia obstétrica, fórmula menstrual, antecedentes de infertilidad y examen fÃsico. Se exploraron asociaciones entre las variables clÃnicas y hormonales y el resultado ultrasonográfico. El 83,1 por ciento de las pacientes anovuladoras mostraron imágenes sugestivas de poliquistosis ovárica. Cuando se asociaron los niveles de testosterona con el ultrasonido, en el 80 por ciento de las que tuvieron testosterona elevada el ultrasonido mostró imágenes de poliquistosis ovárica, sin embargo cuando la testosterona fue normal solo el 42,5 por ciento mostró dichas imágenes. De las 39 pacientes con un Ãndice LH/FSH ³ 2, 32 (82,1 por ciento) tenÃan por imagen ultrasonográfica una poliquistosis ovárica, sin embargo cuando este fue <2, solo el 49 por ciento la presentó. El 75 por ciento de las mujeres con infertilidad exhibÃan un ultrasonido con signos de ovarios poliquÃsticos y el 25 por ciento no. De las 73 pacientes hirsutas, 48 (65,8 por ciento) tenÃan un ultrasonido positivo para poliquÃstosis ovárica, mientras que 25 (34,2 por ciento) no mostraron imágenes sugestivas de dicho trastorno, sin diferencia significativa.(AU)
To determine the association between the result of the ultrasound and the progesterone values, LH/FSH level, testosterone, history of infertility and hirsutism in females with metabolic syndrome. A descriptive cross-sectional study was undertaken among 90 females aged 18-45 with diagnosis of metabolic syndrome. FSH (3-5 days of the menstrual cycle), LH (3-5 days of the menstrual cycle), prolactin (3-5 days of the menstrual cycle), androgens (total testosterone, 3-5 days of the menstrual cycle), progesterone (21-23 days of the menstrual cycle) were determined if they were menstruating; otherwise they were established at any moment. A transvaginal gynecological ultrasound in the early follicular phase was performed if they had menstruation, but if they were amenorrheic it was carried out at any time. A medical history was also made to explore obstetric history, menstrual formula, history of infertility and physical examination. Associations between the clinical and hormonal variables and the ultrasonographic result were investigated. 83.1 percent of the anovulatory showed images suggestive of ovarian polycystosis. When the testosterone levels were associated with the ultrasound, in 80 per cent of those who had an elevated testosterone, the ultrasound showed images of ovarian polycystosis; however, when testosterone was normal, just 42,5 percent had such images. Of the 39 patients with an index ³ 2, 32 (82,1 percent) presented an ultrasonographic image of ovarian polycystosis; however, when it was <2, only 49 percent had them. 75 percent of the females with infertility showed an ultrasound with signs of polycystic ovaries and 25 percent did not. Of the 73 hirsute patients, 48 (65,8 percent) had a positive ultrasound for ovarian polycystosis, whereas 25 (34,2 percent) did not exhibit images suggestive of this disorder, without a significant difference. the association between anovulatory progesterone, elevated levels of testosterone(AU)