Inhaled nitric oxide and high concentrations of oxygen in pediatrics patients with congenital cardiopathy and pulmonary hypertension: report of five cases
Säo Paulo med. j; 116 (1), 1998
Publication year: 1998
Five patients with ages ranging from 6 months to 3 years were analyzed. All received inhaled nitric oxide (NO - 20 parts per million (ppm)) and oxygen (O2 - at a concentration of 90-95 percent) by means of an oxygen hood. Mean Pulmonary Artery Pressure (MPAP), Mean Aortic Pressure (MAoP), Pulmonary Vascular Resitance (PVR) and Systemic Vascular Resistance (SVR) were measured and the calculation of their relationship to pulmonary/systemic flow (Qp/Qs) was performed by the catheterization of the femoral artery vein. Three patients presented reduction in PVR and increase in Qp/Qs. There were no systemic alterations or any side effect from using NO.
Óxido Nítrico/uso terapéutico, Cardiopatías Congénitas/tratamiento farmacológico, Hipertensión Pulmonar/tratamiento farmacológico, Seguridad, Administración por Inhalación, Cardiopatías Congénitas/complicaciones, Hipertensión Pulmonar/complicaciones, Resistencia Vascular/efectos de los fármacos, Arteria Pulmonar/efectos de los fármacos, Oxígeno/farmacología, Óxido Nítrico/farmacología, Exposición por Inhalación