Objective:

To evaluate the efficiency of biological sealant, an autologous fibrin glue, in dermatological surgery.

Design:

Randomized clinical trial Setting: The Dermatology Service of Hospital das Clinicas, Universidade de Campinas (UNICAMP), referral center.

Patients:

14 patients with malign epithelial cutaneoos tumors participated in the evaluation, each having two tumors, generally facial and symmetrical, in order to perform a comparative evaluation on the same individual.

Procedures:

The glue was prepared beforehand with a sample of autologous blood. Surgical extirpation of the tumor was followed by grafts or second intention healing.

Outcomes:

The efficiency of the sealant was then evaluated in relation to hemostasis, adhesion, surgical time and evolution of the granulation tissue, clinically and histologically.

Results:

Immediate hemostasis and graft adhesion, with a significant reduction of surgical time, and in the open wounds there was immediate hemostasis and a clinical increase in granulation tissue, but with no histological differences among the groups on the 7th day.

Conclusion:

It is an adjuvant resource in skin cancer surgery.