Darier's disease: a new paradigm for genetic studies in psychiatric disorders

Cordeiro Júnior, Quirino; Werebe, Daniela Meshulam; Vallada, Homero

Darier's disease: a new paradigm for genetic studies in psychiatric disorders

Cordeiro Júnior, Quirino; Werebe, Daniela Meshulam; Vallada, Homero.

Säo Paulo med. j; 118 (6), 2000

Publication year: 2000

CONTEXT:

One strategy for identifying susceptibility genes for common disorders is to investigate Mendelian diseases, cosegregating with these common disease phenotypes.

CASE REPORT:

A family with seven members is described, in which three members present Darier's disease and depression. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for mood disorder may be located on chromosome 12

Enfermedad de Darier/genética, Depresión/genética, Predisposición Genética a la Enfermedad, Enfermedad de Darier/psicología, Enfermedad de Darier/complicaciones, Cromosomas Humanos Par 12/genética, Segregación Cromosómica/genética, Trastornos del Humor/genética

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