CONTEXT:

Renal cell carcinoma is the third most frequent genitourinary neoplasia, and there is currently an increase in the incidental diagnosis of tumors confined to the kidneys.

OBJECTIVE:

To study the survival of patients with incidental and symptomatic renal tumors who have undergone nephrectomy.

DESIGN:

Retrospective.

SETTING:

Hospital Sírio Libanês and Beneficência Portuguesa de São Paulo.

PARTICIPANTS:

115 patients with diagnosis of renal cell carcinoma, operated on by the same group of surgeons and evaluated by a single pathologist.

MAIN MEASUREMENTS:

Sex, age and diagnosis method, analyzed in two groups, according to the tumor diagnosis: Group 1 with incidental diagnosis and Group 2 with symptomatic tumors. The anatomopathological characteristics and patient survival in both groups were evaluated. A statistical analysis was performed using the Student t, chi-squared, log rank and Kaplan-Meyer tests.

RESULTS:

Among the studied patients, 59(51 percent) had an incidental diagnosis, with 78 percent diagnosed by ultrasonography, 20 percent by computerized tomography scan and 2 percent during surgeries; 56 patients (49 percent) were symptomatic. Tumor locations were equally distributed between the two kidneys, and the surgery was conservative for 24 percent of the incidental and 9 percent of the symptomatic group. In the incidental group only one patient had tumor progression and there was no death, while in the symptomatic group there were 5 progressions and 10 deaths. The 5-year specific cancer-free survival was 100 percent in the incidental and 80 percent in the symptomatic group (p = 0.001) while the disease-free rate was 98 percent in the incidental and 62 percent in the symptomatic group (p < 0001).

CONCLUSION:

Incidental renal tumor diagnosis offers better prognosis, providing longer disease-free survival