ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats

Muñoz, Gustavo Alfredo Ochs de; Kretzmann, Nelson Alexandre; Luján López, Mónica; Kieling, Carlos Oscar; Uribe-Cruz, Carolina; Silva, Luciano Basso da; Osvaldt, Alessandro Bersch; Matte, Ursula

ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats

Muñoz, Gustavo Alfredo Ochs de; Kretzmann, Nelson Alexandre; Luján López, Mónica; Kieling, Carlos Oscar; Uribe-Cruz, Carolina; Silva, Luciano Basso da; Osvaldt, Alessandro Bersch; Matte, Ursula.

Clin. biomed. res; 36 (4), 2016

Publication year: 2016

We investigated the influence of bone marrow cells upon activation of ERK 1/2 in an animal model of 90% PH. Phosphorylated ERK 1/2 was evaluated by western blot. No differences were found between the groups. Thus, increased survival does not appear to be mediated by ERK 1/2 activation (AU)

Quinasas MAP Reguladas por Señal Extracelular/metabolismo, Activación Enzimática/fisiología, Trasplante de Médula Ósea, Fallo Hepático Agudo/terapia, Hepatectomía, Tasa de Supervivencia, Modelos Animales de Enfermedad

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