Neumonía intersticial inducida por bloqueo androgénico máximo como tratamiento de cáncer de próstata avanzado: Report of one case
Fatal interstitial lung disease associated with maximum androgen blockade
Rev. méd. Chile; 144 (10), 2016
Publication year: 2016
Maximum androgen blockade is the standard endocrine treatment for advanced prostate cancer. Interstitial lung disease in different degrees of severity, with low mortality and excellent response to treatment may appear with its use. We report a 77 years old patient with advanced prostate cancer who developed severe and progressive respiratory failure associated to bilateral pulmonary infiltrates, attributed to the direct effect of maximum androgen blockade. Despite the therapeutic efforts, the patient died. Lung pathology revealed Usual Interstitial Pneumonia.
Antagonistas de Andrógenos/efectos adversos, Antinematodos/efectos adversos, Enfermedades Pulmonares Intersticiales/inducido químicamente, Adenocarcinoma/tratamiento farmacológico, Anilidas/efectos adversos, Biopsia, Progresión de la Enfermedad, Resultado Fatal, Enfermedades Pulmonares Intersticiales/patología, Nitrilos/efectos adversos, Neoplasias de la Próstata/tratamiento farmacológico, Tomografía Computarizada por Rayos X, Compuestos de Tosilo/efectos adversos