Noninvasive ventilation during immediate postoperative period in cardiac surgery patients: systematic review and meta-analysis
Rev. bras. cir. cardiovasc; 32 (4), 2017
Publication year: 2017
Abstract Objective:
To verify the effectiveness of noninvasive ventilation compared to conventional physiotherapy or oxygen therapy in the mortality rate and prevention of pulmonary complications in patients during the immediate postoperative period of cardiac surgery.Methods:
Systematic review and meta-analysis recorded in the International Prospective Register of Ongoing Systematic Reviews (number CRD42016036441).The research included the following databases:
MEDLINE, Cochrane Central, PEDro, LILACS and manual search of the references of studies published until March 2016. The review included randomized controlled trials with patients during the immediate postoperative period of cardiac surgery, which compared the use of noninvasive ventilation, BiLevel modes, continuous positive airway pressure, intermittent positive pressure breathing and positive pressure ventilation with conventional physiotherapy or oxygen therapy, and assessed the mortality rate, occurrence of pulmonary complications (atelectasis, pneumonia, acute respiratory failure, hypoxemia), reintubation rate, ventilation time, time spent in the intensive care unit (ICU), length of hospital stay and partial pressure of oxygen.Results:
Among the 479 selected articles, ten were included in the systematic review (n=1050 patients) and six in the meta-analysis. The use of noninvasive ventilation did not significantly reduce the risk for atelectasis (RR: 0.60; CI95% 0.28-1.28); pneumonia (RR: 0.20; CI95% 0.04-1.16), reintubation rate (RR: 0.51; CI95%: 0.15-1.66), and time spent in the ICU (-0.04 days; CI95%: -0.13; 0.05).Conclusion:
Prophylactic noninvasive ventilation did not significantly reduce the occurrence of pulmonary complications such as atelectasis, pneumonia, reintubation rate and time spent in the ICU. The use is still unproven and new randomized controlled trials should be carried out.
Procedimientos Quirúrgicos Cardíacos/rehabilitación, Presión de las Vías Aéreas Positiva Contínua/métodos, Puente de Arteria Coronaria/efectos adversos, Puente de Arteria Coronaria/mortalidad, Ventilación no Invasiva/métodos, Ventilación no Invasiva/estadística & datos numéricos, Terapia por Inhalación de Oxígeno, Neumonía/terapia, Complicaciones Posoperatorias, Periodo Posoperatorio, Atelectasia Pulmonar/terapia, Ensayos Clínicos Controlados Aleatorios como Asunto, Factores de Tiempo