From April 1987 to December 1990, a total of 3895 persons participated in our anonymous HIV-antybody prevalence study in groups at risk for sexually-acquired HIV infection. Male travestied prostitutes had the highest HIV-antibody seroprevalence (> 30 precent). Seventy five percent of all known male travestied prostitutes known participate in self-help groups. More than 3/4 were under 30 years of age and had a relatively high level of education for our cournty (none were illiterate). More than one half had been working the streets for over 5 years. Alcohol use was heavy with about one half of the group professing to drinking more than one liter of alcohlic beverages per day and nearly one half to consuming barbiturates at the same time. Consistent condom use was low, with only 7 percent claiming to use condoms all the time, while nearly 20 percent never use them and over 70 percent admitted to use condoms only some of the time. One half professed tpo have had from 50 to over 100 different clients in the 30 days preceding the interview and claimed that about 75 percent of those clients were currently married or had been married