In 1999, the countries of the Americas reported 73 cases of human rabies. This represents a 16.1 percent reduction in relation to the preceding year, and a 71 percent reduction compared with 1990, thus continuing the downward trend of the disease during the decade. In Latin America, all subregions experienced reductions in the number of cases in humans, with the exception of the Andean Area, which had an increase of 38.1 percent. Reductions in the other subregions were 62.5 percent in Cantral America, 55.6 percent in the Southern Cone, 50 percent in the Latin Caribbean, 40 percent in Mexico, and 10.7 percent in Brazil. The non-Latin Caribbean and North American subregions did not report any occurence of human cases