Results: 15

In vivo efficacy and safety of artemether-lumefantrine and amodiaquine-artesunate for uncomplicated Plasmodium falciparum malaria in Mozambique, 2018

Malar. j. (Online); 20 (1), 2021
Artemisinin-based combination therapy (ACT) has been the recommended first-line treatment for uncomplicated malaria in Mozambique since 2006, with artemether-lumefantrine (AL) and amodiaquine-artesunate (AS-AQ) as the first choice. To assess efficacy of currently used ACT, an in vivo therapeutic efficacy...

The preoperative risk tool SURPAS accurately predicts outcomes in emergency surgery

Am. j. surg; 222 (3), 2021
O Sistema de Avaliação Pré-operatória de Risco Cirúrgico (SURPAS) utiliza oito variáveis para prever com precisão complicações pós-operatórias , mas não foi suficientemente estudado em cirurgia de emergência. Avaliamos o SURPAS em cirurgia de emergência, comparando-o com o Emergency Surgery...

Quantifying the gender gap in the HIV care cascade in southern Mozambique: We are missing the men

PLoS One; 16 (2), 2021
Uptake of HIV testing and antiretroviral therapy (ART) services during antenatal care (ANC) in rural Mozambique is disappointing. To nurture supportive male engagement in ANC services, we partnered with traditional birth attendants and trained a new type of male-to-male community health agent, "Male Cham...

TB sequel: incidence, pathogenesis and risk factors of long-term medical and social sequelae of pulmonary TB - a study protocol

BMC pulm. med; 19 (1), 2019
Background: Up to fifty percent of microbiologically cured tuberculosis (TB) patients may be left with permanent, moderate or severe pulmonary function impairment. Very few studies have systematically examined pulmonary outcomes in patients to understand the pathophysiologic basis and long-term socio-eco...

Desenvolvimento e implementação de um modelo de data warehouse para integração de sistemas electrónicos de seguimento de pacientes hiv+: um estudo de caso da província da zambézia, moçambique

Desde 2007, o Sector de Saúde em Moçambique, incluindo a Província da Zambézia, está a implementar diferentes Sistemas Electrónicos para Seguimento de Pacientes (SESP) HIV+ em diversas Unidades Sanitárias (US). Estes sistemas estão sendo implementados de forma isolada em ...

Relatório das Actividades Desenvolvidas durante o ano 2017

DOTS: a taxa de notificação de Tuberculose (TB) todas as formas aumentou de 237/100,000 em 2015 para 319/100,000 hab em 2017. Em termos de número de casos, foi notificado em 2017 um total de 86.515 casos de TB todas as formas, correspondendo à um índice de cumprimento da meta para 2017 de pouco mais...

Engagement of Men in Antenatal Care Services: Increased HIV Testing and Treatment Uptake in a Community Participatory Action Program in Mozambique

AIDS behav; 20 (9), 2016
Uptake of HIV testing and antiretroviral therapy (ART) services during antenatal care (ANC) in rural Mozambique is disappointing. To nurture supportive male engagement in ANC services, we partnered with traditional birth attendants and trained a new type of male-to-male community health agent, "Male Cham...

Nevirapine or efavirenz for tuberculosis and HIV coinfected patients: exposure and virological failure relationship

J. antimicrob. chemother; 70 (1), 2015
Objectives: We describe nevirapine and efavirenz exposure on and off tuberculosis treatment and consequences for virological efficacy and tolerance in patients included in the ANRS 12146/12214-CARINEMO trial. Methods: Participants were randomly selected to receive either nevirapine at 200 mg twice daily...

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-negative women: a multicentre randomized controlled trial

PloS med; 11 (9), 2014
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended by WHO to prevent malaria in African pregnant women. The spread of SP parasite resistance has raised concerns regarding long-term use for IPT. Mefloquine (MQ) is the most promising of avai...

In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated falciparum malaria in children: a multisite, open-label, two-cohort, clinical trial in Mozambique

Malar. j. (Online); 13 (309), 2014
Background: Mozambique adopted artemisinin-based combination therapy (ACT) for the treatment of uncomplicated Plasmodium falciparum malaria in the year 2006, and since 2009 artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) have been proposed as alternative first-line treatments. A multicentr...