Results: 1300
Spatio-seasonal modeling of the incidence rate of malaria in Mozambique
Malar. j. (Online); 7 (228), 2008
Background: The objective was to study the seasonal effect on the spatial distribution of the incidence of malaria in children under 10 years old living in the Manhiça district, Mozambique.
Methods: The data of the clinical malaria incidence were obtained from a study of two cohorts of children followed...
Impact of intermittent preventive treatment with sulfadoxine-pyrimethamine on antibody responses to erythrocytic-stage Plasmodium falciparum antigens in infants in Mozambique
Clin. vaccine immunol; 15 (8), 2008
We evaluated the impact of intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP), which was given at ages 3, 4, and 9 months through the Expanded Program on Immunization (EPI), on the development of antibody responses to Plasmodium falciparum in Mozambique. Immunoglobuli...
Antibodies, Protozoan/blood, Antibodies, Protozoan/immunology, Antibodies, Protozoan/genetics, Antimalarials/administration & dosage, Antimalarials/therapeutic use, Malaria, Falciparum/immunology, Malaria, Falciparum/prevention & control, Plasmodium falciparum/immunology, Pyrimethamine/administration & dosage, Mozambique, Recombinant Proteins/genetics, Recombinant Proteins/immunology
Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique
Malar. j. (Online); 7 (115), 2008
In late 2002, the health authorities of Mozambique implemented sulphadoxine-pyrimethamine (SP)/amodiaquine (AQ) as first-line treatment against uncomplicated falciparum malaria. In 2004, this has been altered to SP/artesunate in line with WHO recommendations of using Artemisinin Combination Therapies (AC...
Pyrimethamine/pharmacology, Protozoan Proteins/genetics, Malaria, Falciparum/epidemiology, d0161330, d0138120, Mozambique/epidemiology, Ligases, Drug Combinations, Drug Resistance/genetics, Ezetimibe, Simvastatin Drug Combination/therapeutic use, Pyrimethamine/supply & distribution, Pharmaceutical Preparations, Haplotypes/genetics, Malaria, Falciparum/therapy, Malaria, Falciparum/parasitology, Plasmodium falciparum/radiation effects, Plasmodium falciparum/isolation & purification, Protozoan Proteins/standards, Sulfadoxine/pharmacology
Estudo de avaliação multi-nacional
Clinical Laboratory Techniques, Primary Health Care, Mozambique, HIV, Acquired Immunodeficiency Syndrome, Rural Population, Maternal Health Services, Health Impact Assessment, Tuberculosis, Malaria, 32395, Data Interpretation, Statistical, Quality Assurance, Health Care, Health Surveillance System, Epidemiological Monitoring, Pregnant Women, Public Reporting of Healthcare Data
Molecular Markers of Resistance to Sulfadoxine-Pyrimethamine during Intermittent Preventive Treatment for Malaria in Mozambican Infants
J. infect. dis; 197 (12), 2008
Background. Intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP) is a po tential malaria control strategy. There is concern about the impact that increasing in vivo resistance to SP has on the efficacy of IPTi, as well as about the potential contribution of IPTi to incr...
Invasive Haemophilus influenzae disease in children less than 5 years of age in Manhiça, a rural area of southern Mozambique
Trop. med. int. health; 13 (6), 2008
Objective: To measure the disease burden and epidemiological characteristics of invasive Haemophilus influenzae in rural Mozambican children. Methods: As part of the clinical management of children admitted to Manhiça District Hospital, blood and cerebrospinal fluid samples were collected between May 20...
Malaria in rural Mozambique. Part II: children admitted to hospital
Malar. j. (Online); 7 (37), 2008
Background: Characterization of severe malaria cases on arrival to hospital may lead to early recognition and improved management. Minimum community based-incidence rates (MCBIRs) complement hospital data, describing the malaria burden in the community. Methods: A retrospective analysis of all admitted m...
Malaria in rural Mozambique. Part I: children attending the outpatient clinic
Malar. j. (Online); 7 (36), 2008
Background: Malaria represents a huge burden for the health care services across Africa. Describing malaria attending health services contributes to quantify the burden and describe the epidemiology and clinical presentation.
Methods: Retrospective analysis of data collected through the Manhiça morbidit...
Malaria, Falciparum/diagnosis, Plasmodium falciparum/isolation & purification, Rural Health Services/statistics & numerical data, Malaria, Falciparum/therapy, Malaria, Falciparum/epidemiology, Malaria, Falciparum/prevention & control, Ambulatory Care Information Systems/statistics & numerical data, Risk Factors, Mozambique/epidemiology
Clinical malaria in african pregnant women
Malar. j. (Online); 7 (27), 2008
Background: There is a widespread notion, based on limited information, that in areas of stable malaria transmission most pregnant women with Plasmodium falciparum infection are asymptomatic. This study aim to characterize the clinical presentation of malaria in African pregnant women and to evaluate the...