Results: 227

Mozambique’s Community Antiretroviral Therapy Support Group Program: The Role of Social Relationships in Facilitating HIV/ AIDS Treatment Retention

AIDS behav; 23 (9), 2019
The Community Antiretroviral (ARV) Therapy Support Group (CASG) program aims to address low retention rates in Mozambique’s HIV treatment program and the absorptive capacity of the country’s health facilities. CASG provides patients with the opportunity to form groups, whose members provide peer supp...

Tipping the balance towards long-term retention in the HIV care cascade: A mixed methods study in southern Mozambique

PLoS One; 14 (9), 2019
Background: The implementation of quality HIV control programs is crucial for the achievement of the UNAIDS 90-90-90 targets and to motivate people living with HIV (PLWHIV) to link and remain in HIV-care. The aim of this mixed method cross-sectional study was to estimate the linkage and long-term retenti...

Barriers to access and adherence to tuberculosis services, as perceived by patients: A qualitative study in Mozambique

PLOS ONE; 14 (7), 2019
Tuberculosis (TB) continues to be a leading cause of death in Sub-Saharan Africa, including Mozambique. While diagnostic methods and total notifications are improving, significant gaps remain between total numbers of TB cases annually, and the number that are notified. The purpose of this study was to el...

Cost-per-diagnosis as a metric for monitoring cost-effectiveness of HIV testing programmes in low-income settings in southern Africa: health economic and modelling analysis

J. int. aids soc; 22 (7), 2019
Introduction: As prevalence of undiagnosed HIV declines, it is unclear whether testing programmes will be cost-effective. To guide their HIV testing programmes, countries require appropriate metrics that can be measured. The cost-per-diagnosis is potentially a useful metric. Methods: We simulated a serie...

High prevalence of HIV, HBsAg and anti-HCV positivity among people who injected drugs: results of the first bio-behavioral survey using respondent-driven sampling in two urban areas in Mozambique

BMC infect. dis; 19 (1), 2019
Few countries in sub-Saharan Africa know the magnitude of their HIV epidemic among people who inject drugs (PWID). This was the first study in Mozambique to measure prevalence of HIV, HBV, and HCV, and to assess demographic characteristics and risk behaviors in this key population. Methods: We used resp...

Age targeting and scale-up of voluntary medical male circumcision in Mozambique

PLos ONE; 14 (2), 2019
Background: The voluntary medical male circumcision (VMMC) program in Mozambique aimed to increase male circumcision (MC) coverage to 80 percent among males ages 10 to 49 by 2018. Given the difficulty in attracting adult men over age 20 for circumcision, Mozambique became interested in assessing its age-...

Hepatocellular Carcinoma: Clinical-pathological features and HIV infection in Mozambican patients

Mozambique had been ranked among the countries with the highest global incidence of HCC with chronic hepatitis B infection and high exposure to aflatoxin-B1 (AFB1) being major risk factors. Indeed, HCC remains one of the most frequent cancer in Maputo. On the other hand, Mozambique has a high prevalence ...

Self-reported non-receipt of HIV test results: A silent barrier to HIV epidemic control in Mozambique

PLos ONE; 14 (10), 2019
Introduction: People living with HIV (PLHIV) and who are aware of their HIV status can access and benefit from antiretroviral therapy (ART) with subsequent individual and public health benefits; however, many PLHIV are unaware of their HIV status. We assessed the magnitude and determinants of self-report...

Conhecimento da serologia para o HIV e uso de preservativos entre as Mulheres Trabalhadoras de Sexo vivendo com o HIV em três zonas urbanas de Moçambique, 2011-2012

O presente trabalho trata-se de uma análise secundária de dados de inquéritos transversais realizados com Mulheres Trabalhadoras de Sexo, em Moçambique, em 2011-2012, o qual foi realizado em três áreas urbanas de Moçambique, Maputo, Beira e Nampula. A análise secundária foi desenvolvida em 2016,...

Regulatory T cell abundance and activation status before and after priming with HIVIS-DNA and boosting with MVA-HIV/rgp140/GLA-AF may impact the magnitude of the vaccine-induced immune responses

Immunobiol., Suppl; 223 (12), 2018
Little is known about regulatory CD4 T cells (Tregs) in the context of HIV vaccines. Tregs can be differentiated into resting (FoxP3+CD45RA+ - rTregs), activated (FoxP3HighCD45RA- - aTregs) and memory (FoxP3LowCD45RA- - mTregs). Tregs, as CD4 T cells, are also frequent targets for HIV infection. We studi...