Background: Concerning gaps in the HIV care continuum compromise individual and population health. We evaluated a combination intervention strategy (CIS) targeting prevalent barriers to timely linkage and sustained retention in HIV care in Mozambique.
Methods and findings: In this cluster-randomized tria...
Anti-HIV Agents/administration & dosage,
Cluster Analysis,
Combined Modality Therapy,
Early Medical Intervention/methods,
Follow-Up Studies,
HIV Infections/diagnosis,
HIV-1/drug effects,
Health Behavior,
Motivation,
Patient Compliance,
Epidemiology,
Therapeutics,
Mozambique,
HIV Infections/therapy
Floridia, Marco;
Ciccacci, Fausto;
Andreotti, Mauro;
Hassane, Archa;
Sidumo, Zita;
Magid, Nurja A;
Sotomane, Horacio;
David, Muhlavasse;
Mutemba, Elsa;
Cebola, Junia;
Mugunhe, Remigio José;
Riccardi, Fabio;
Marazzi, Maria Cristina;
Giuliano, Marina;
Palombi, Leonardo;
Mancinelli, Sandro.
Tuberculosis is a major health concern in several countries, and effective diagnostic algorithms for use in human
immunodeficiency virus (HIV)–positive patients are urgently needed.
Methods. At prescription of antiretroviral therapy, all patients in 3 Mozambican health centers were screened for tubercu...
Algorithms,
Antiretroviral Therapy, Highly Active,
Antitubercular Agents,
HIV Infections/drug therapy,
Lipopolysaccharides,
Molecular Diagnostic Techniques,
Mozambique,
Mycobacterium tuberculosis,
Prevalence,
Sensitivity and Specificity,
Tuberculosis, Pulmonary/diagnosis,
Sputum
Introduction: The scale-up of effective HIV viral load (VL) testing is an urgent public health priority. Implementation of testing is supported by the availability of accurate, nucleic acid based laboratory and point-of-care (POC) VL technologies and strong WHO guidance recommending routine testing to id...
Martins-Fonteyn, Emilia;
Loquiha, Osvaldo;
Baltazar, Cynthia;
Thapa, Subash;
University of California, San Francisco – USA, of Global Health Sciences;
Raimundo, Ines;
Hens, Niel;
Aerts, Marc;
Meulemans, Herman;
Degomme, Olivier;
Wouters, Edwin.
Background: Information dealing with social and behavioural risk factors as well as their mechanisms among
Mozambican migrants working in South African mines remains undocumented. This study aims to understand the
various factors influencing HIV-related risk behaviours and the resulting HIV positive stat...
Chang, joy;
Sousa, amina de;
Sabatier, jennifer;
Assane, mariamo;
Zhang, guoqing;
Bila, dulce;
Vaz, paula;
Alfredo, charity;
Cossa, Loide;
Bhatt, Nilesh;
Koumans, emilia, h;
Yang, chunfu;
Rivadeneira, emilia;
Jani, ilesh;
Houston, james, c.
Quantitative plasma viral load (VL) at 1000 copies /mL was recommended as the threshold to confirm antiretroviral therapy (ART) failure by the World Health Organization (WHO). Because of ongoing challenges of using plasma for VL testing in resource-limited settings (RLS), especially for children, this st...
Decroo, Tom;
Telfer, Bárbara;
Dores, Carla Das;
Branco, Ricardo A;
Santos, Natacha Dos;
Mkwamba, Alec;
Dezembro, Sergio;
Joffrisse, Mariano;
Ellman, Tom;
Metcalf , Carol.
Objectives
Estimate the effect of participation in Community ART Groups (CAG) versus individual care on retention-in-care (RIC) on antiretroviral therapy (ART).
Design
Retrospective cohort study.
Setting
High levels of attrition (death or loss-to-follow-up (LTFU) combined) on ART indicate that delivery...
Ndam, Nicaise Tuikue;
Mbuba, Emmanuel;
Gonzalez, Raquel 5;
Cistero, Pau;
Kariuki, Simon;
Sevene, Esperança;
Ruperez, María 5 6;
Fonseca, Ana Maria 5 9;
Vala, Anifa;
Muculuve, Sonia;
Jimenez, Alfons;
Quinto, Llorenç;
Ouma, Peter;
Ramharter, Michael;
Desai, Meghna;
Macete, Eusebio;
Cot, Michel;
Menendez, Clara;
Mayor, Alfredo.
Resistance and tolerance to Plasmodium falciparum can determine the progression of malaria disease. However, quantitative evidence of tolerance is still limited. We investigated variations in the adverse impact of P. falciparum infections among African pregnant women under different intensities of malari...
HIV Infections/complications,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/transmission,
Microscopy,
Placenta,
Plasmodium falciparum/immunology,
Pregnancy Complications, Infectious,
Pregnancy Outcome,
Real-Time Polymerase Chain Reaction
Gonzalez, Raquel;
Ruperez, , Marı´a;
Sevene, Esperanc¸a;
Vala, Anifa;
Maculuve, So´nia;
Bulo, Helder;
Nhacolo, Arse´nio;
Mayor, Alfredo;
Aponte, John J;
Macete, Euse´bio;
Medenendez, Clara.
The HIV epidemic is concentrated in sub-Saharan Africa. However, limited information exists on its impact on women and infant's health since the introduction of antiretroviral drugs in this region, where health resources are often scarce.
Methods: The effect of HIV infection on maternal health, birth ou...
Anti-HIV Agents/therapeutic use,
HIV Infections/therapy,
HIV Infections/epidemiology,
Maternal Mortality,
Infant, Newborn,
Parturition,
d0000680970,
Pregnancy Complications, Infectious/therapy,
Pregnancy Complications, Infectious/epidemiology,
Pregnancy Outcome/epidemiology,
Prospective Studies,
Mozambique
Background
Studies have been conducted in developing countries using SMS to communicate with patients to reduce the number of missed appointments and improve retention in treatment, however; very few have been scaled up. One possible reason for this could be that patients or staff are dissatisfied with t...
Tuberculosis (TB) remains an important public health concern and a leading cause of disease and death worldwide. Mozambique is one of the few high-burden countries where incidence rates have not improved in recent years. The estimated TB incidence rate in 2014 was 552 cases per 100 000 population and t...
