Results: 270

The secret life of young adolescents living with HIV in northern Mozambique - a mixed methods study

BMC public health (Online); 21 (1650), 2018
Background: In Mozambique, HIV infection remains a leading cause of adolescent mortality. With advances in antiretroviral treatment (ART), the population of adolescents living with vertically-acquired HIV is growing. Most studies of adolescents living with HIV (ALHIV) focus on older youth with horizontal...

Early Declines in Vaccine Type Pneumococcal Carriage in Children Less Than 5 Years Old After Introduction of 10-valent Pneumococcal Conjugate Vaccine in Mozambique

Pneumococcal carriage is a precursor of invasive pneumococcal disease. Mozambique introduced 10-valent pneumococcal conjugate vaccine (PCV10) in April 2013, using a 3-dose schedule without a booster. We evaluated PCV10 impact on pneumococcal carriage and colonization density by HIV status. Methods: We c...

Knowledge about HIV, HBV and HCV modes of transmission among pregnant women in Nampula - Mozambique

AIDS care; 30 (9), 2018
The assessment of pregnant women's knowledge about modes of infections transmission is essential to tailor programs to their needs. This study aimed to assess knowledge about human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) among pregnant women in Nampula - Mozambi...

Partners-based HIV treatment for seroconcordant couples attending antenatal and postnatal care in rural Mozambique: A cluster randomized trial protocol

Contemp. clin. trials; 70 (), 2018
Background: In resource-limited rural settings, scale-up of services to eliminate mother-to-child transmission of HIV has not been as effective as in better resourced urban settings. In sub-Saharan Africa, women often require male partner approval to access and remain engaged in HIV care. Our study will...

The role of HIV infection in the etiology and epidemiology of diarrheal disease among children aged 0–59 months in Manhiça District, Rural Mozambique

Int. j. infect. dis; 73 (4), 2018
The Global Enteric Multicenter Study enrolled children with moderate-to-severe diarrhea (MSD) and less-severe diarrhea (LSD) between December 2007 and November 2012. One to three controls for MSD cases and one per LSD case were enrolled and matched by age, sex, and neighborhood. All children were tested ...

Delayed diagnosis and treatment of tuberculosis in HIV+ patients in Mozambique: A cost-effectiveness analysis of screening protocols based on four symptom screening, smear microscopy, urine LAM test and Xpert MTB/RIF

PLos ONE; 13 (7), 2018
Background: Tuberculosis (TB) represents the ninth leading cause of death worldwide. In 2016 are estimated 1.3 million TB deaths among HIV negative people and an additional 374,000 deaths among HIV positive people. In 2016 are estimated 1.4 million new cases of TB in people living with HIV (PLHIV), 74% o...

Effect of point-of-care early infant diagnosis on antiretroviral therapy initiation and retention of patients

AIDS res. hum. retrovir; 32 (11), 2018
HIV/AIDS is a leading cause of infant mortality in sub-Saharan Africa. Despite significant improvements in preventing vertical transmission, in the 21 Global Plan priority countries in sub-Saharan Africa, over 100 000 infants are infected with HIV annually and only 50% access life-saving antiretroviral t...

Bisexual and Bidirectional: Assessing the Potential for HIV Bridging in Mozambique

AIDS behav; 22 (7), 2018
African men who have sex with men (MSM) frequently, and often concurrently, have female partners, raising concerns about HIV sexual bridging. We explored potential HIV transmission in Mozambique from and to female partners of MSM focusing on preferred anal sex role and circumcision status. Data collected...

Performance of point-of-care birth HIV testing in primary health care clinics: An observational cohort study

PLOS ONE; 13 (6), 2018
Worldwide only 43% of infants infected with HIV have access to antiretroviral treatment (ART). Despite significant global efforts to expand access to paediatric treatment, coverage lags behind adult ART and may not reach the 90-90-90 goals by 2020 as set by UNAIDS [2]. Resolving this paediatric ART gap i...

Pathways of care for HIV infected children in Beira, Mozambique: pre-post intervention study to assess impact of task shifting

Background: In 2013, Mozambique implemented task-shifting (TS) from clinical officers to maternal and child nurses to improve care for HIV positive children < 5 years old. A retrospective, pre-post intervention study was designed to evaluate effectiveness of a new pathway of care in a sample of Beira Dis...