Fonseca, ana maria;
Quinto, llorenç;
Jiménez, alfons;
González, raquel;
Bardají, azucena;
Maculuve, sonia;
Dobaño, carlota;
Rupérez, maria;
Vala, anifa;
Aponte, john, j;
Sevene, esperanza;
Macete, Eusebio;
Menéndez, clara;
Mayor, alfredo.
Background: Pregnant women exposed to Plasmodium falciparum generate antibodies against VAR2CSA, the parasite protein that mediates adhesion of infected erythrocytes to the placenta. There is a need of high-throughput tools to determine the fine specificity of these antibodies that can be used to identif...
Antibodies, Protozoan/blood,
Antibodies, Protozoan/immunology,
Antigens, Protozoan/genetics,
Antigens, Protozoan/immunology,
Antigens, Protozoan/metabolism,
Dried Blood Spot Testing,
Erythrocytes/parasitology,
Immunoassay,
Immunoglobulin G/blood,
Malaria, Falciparum/diagnosis,
Plasmodium falciparum/isolation & purification,
Pregnancy
Muianga, argentina felisbela;
Watson, robert;
Varghese, anitha;
Chongo, inocencio salvador;
António, virgilio;
Chelene, imelda;
Inalda, flora;
Monteiro, vanessa;
Ali, Sadia;
Hewson, roger;
Gudo, eduardo samo.
Objective: Despite its geographical spread, the epidemiology of Crimean-Congo haemorrhagic fever (CCHF) in Sub-Saharan Africa is incompletely understood and its occurrence in Mozambique is unknown. This study was conducted with the aim of investigating the occurrence of CCHF virus (CCHFV) among febrile p...
Hemorrhagic Fever, Crimean/blood,
Hemorrhagic Fever Virus, Crimean-Congo/immunology,
Enzyme-Linked Immunosorbent Assay,
Antibodies, Viral,
Mozambique,
Hemorrhagic Fever, Crimean/diagnosis,
Hemorrhagic Fever, Crimean/epidemiology,
Immunoglobulin G/immunology,
Antibodies, Viral/blood,
Antibodies, Viral/immunology
Hantavírus são vírus RNA pertencentes à família Bunyaviridae transmitidos por roedores silvestres de diferentes espécies. Em humanos, os hantavírus estão associados a duas síndromes clínicas: a febre hemorrágica com síndrome renal, descrita na Europa, África e Ásia e a síndrome pulmonar po...
Background: Rift Valley fever virus (RVFV) remains heavily neglected in humans in Mozambique, even though recent outbreaks were reported in neighboring countries in humans and several cases of RVFV in cattle were reported in several districts in Mozambique.
Findings: We conducted a cross sectional study...
Rift Valley fever virus/genetics,
Antibodies, Viral,
Cross-Sectional Studies,
Enzyme-Linked Immunosorbent Assay,
Immunoglobulin G,
Real-Time Polymerase Chain Reaction,
Mozambique,
Rift Valley Fever/diagnosis,
Rift Valley Fever/epidemiology,
Rift Valley fever virus/immunology,
Serologic Tests,
Mozambique/epidemiology
Background: Rubella and congenital rubella syndrome are highly underreported and neglected in most sub-Saharan countries and vaccination has not yet been incorporated into their national immunization schedules. In this study, we investigated the frequency of immunoglobulin M antibodies against rubella an...
Middle Aged,
Infant, Newborn,
Immunoglobulin M/blood,
Immunoglobulin G/blood,
Child, Preschool,
Birth Rate,
Antibodies, Viral/blood,
Mozambique/epidemiology,
Pregnancy,
Public Health Surveillance,
Retrospective Studies,
Rubella/epidemiology,
Rubella/immunology,
Rubella/prevention & control,
Rubella Syndrome, Congenital,
Rubella Vaccine,
Seroepidemiologic Studies,
Young Adult
Mayor, Alfredo;
Bardají, Azucena;
Macete, Eusebio;
Nhampossa, Tacilta;
Fonseca, Ana Maria;
González, Raquel;
Maculuve, Sonia;
Cisteró, Pau;
Rupérez, Maria;
Campo, Joe;
Vala, Anifa;
Sigaúque, Betuel;
Jiménez, Alfons;
Machevo, Sonia;
Fuente, Laura de la;
Nhama, Abel;
Luis, Leopoldina;
Aponte, John J;
Acácio, Sozinho;
Nhacolo, Arsenio;
Chitnis, Chetan;
Dobaño, Carlota;
Sevene, Esperanza;
Alonso, Pedro Luis;
Menéndez, Clara.
Background: Prevention of reinfection and resurgence is an integral component of the goal to eradicate malaria. However, the adverse effects of malaria resurgences are not known.
Methods: We assessed the prevalence of Plasmodium falciparum infection among 1819 Mozambican women who delivered infants betwe...
Antibodies, Protozoan/blood,
Immunoglobulin G/blood,
Malaria, Falciparum/classification,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/immunology,
Mozambique/epidemiology,
Parasite Load,
Parity,
Plasmodium falciparum/immunology,
Plasmodium falciparum/isolation & purification,
Pregnancy Complications, Infectious/classification,
Pregnancy Complications, Infectious/epidemiology,
Pregnancy Complications, Infectious/immunology,
Severity of Illness Index
A primary concern for the RTS,S malaria vaccine candidate is duration of protection. The ongoing Phase III trial reported evidence of waning efficacy within the first year following vaccination. Multiple Phase IIb trials demonstrated early waning of efficacy. The longest duration of protection for RTS,S ...
Immunoglobulin G/blood,
Antibodies, Protozoan/blood,
Malaria Vaccines/immunology,
Malaria Vaccines/therapeutic use,
Mozambique,
Malaria, Falciparum/prevention & control,
Parasitemia/prevention & control,
Randomized Controlled Trials as Topic,
Plasmodium falciparum
Quelhas, Diana;
Jimenez, Alfons;
Quito, Llorenç;
Casas, Elisa Serra;
Mayor, Alfredo a d;
Cistero, Pau;
Puyol, Laura;
Wilson, Danny W. e;
Richards, Jack S;
Nhampossa, Tacilta;
Macete, Eusebioa;
Aide, Pedro;
Sanz, Sergi;
Aponte, John J;
Alonso, Pedro L;
Beeson, James G;
Menendez, Clara;
Dobano, Carlota.
This study aimed to evaluate whether intermittent preventive treatment in infants with sulfadoxine-pyrimethamine (IPTi-SP) had an effect on the acquisition of IgG against Plasmodium falciparum variant surface antigens (VSA) and growth-inhibitory antibodies in Manhiça, Mozambique. In addition, we assesse...
Antibodies, Protozoan,
d0109630,
Antibodies, Protozoan/blood,
Antibody Formation/radiation effects,
Antigens, Protozoan/immunology,
Antigens, Surface/immunology,
Antineoplastic Combined Chemotherapy Protocols/chemistry,
Immunoglobulin G/blood,
Malaria, Falciparum/blood,
Malaria, Falciparum/immunology,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/prevention & control,
Membrane Proteins/immunology,
Plasmodium falciparum/immunology,
Plasmodium falciparum/pathogenicity,
Protozoan Proteins/immunology,
Mozambique
Background: The optimum age for measles vaccination varies from country to country and thus a standardized vaccination schedule is controversial. While the increase in measles vaccination coverage has produced significant changes in the epidemiology of infection, vaccination schedules have not been adjus...
Mozambique,
Antibody Formation,
Mouth Mucosa/virology,
Urban Population,
Immunity,
Immunoglobulin G/analysis,
Mass Vaccination,
Measles/immunology,
Measles Vaccine/immunology,
Measles/prevention & control,
Measles/virology,
Disease Susceptibility/immunology,
Disease Susceptibility/virology,
Antibodies, Viral/immunology,
Immunoglobulin M/analysis,
Antibodies, Viral/analysis,
Measles Vaccine/administration & dosage,
Measles virus/immunology
