Abílio, ana paula;
Obi, emmanuel;
Koenker, hannah;
Babalola, stella;
Saifodine, abuchahama;
Zulliger, rose;
Swamidoss, Isabel;
Leon, gabriel ponce de;
Alfai, Eunice;
Blaufuss, sean;
Olapeju, Bolanle;
Harig, hunter;
Kilian, albert.
Malaria prevention with long-lasting insecticidal nets (LLINs) has seen a tremendous scale-up in sub-Saharan Africa in the last decade. To sustain this success, it is important to understand how long LLINs remain in the households and continue to protect net users, which is termed durability. This inform...
Soro, Laura Fuente;
Varela, Elisa López;
Augusto, Orvalho;
Bernardo, Edson Luis;
Sacoor, Charfudin;
Nhacolo, Ariel;
Castillo, Paula Ruiz;
Alfredo, Charity;
Karajeanes, Esmeralda;
Vaz, Paula;
Naniche, Denise.
Patients lost to follow-up (LTFU) over the human immunodeficiency virus (HIV) cascade have poor clinical outcomes and contribute to onward HIV transmission. We assessed true care outcomes and factors associated with successful reengagement in patients LTFU in southern Mozambique.
Newly diagnosed HIV-posi...
Introduction: Viral load testing is essential to manage HIV disease, especially in infants and children. Early infant diagnosis (EID) is performed using nucleic-acid testing in children under 18 months. Resource-limited health systems face severe challenges to scale-up both viral load and EID to unpreced...
HIV Infections/diagnosis,
HIV Infections/virology,
HIV-1/genetics,
HIV-1/isolation & purification,
HIV-1/physiology,
Infant, Newborn, Diseases/diagnosis,
Infant, Newborn, Diseases/virology,
Mozambique,
Sensitivity and Specificity,
Prospective Studies,
Viral Load/methods,
Viremia/diagnosis,
Viremia/virology
Fernández-Luis, Sheila;
Nhampossa, Tacilta;
Fuente-Soro, Laura;
Augusto, Orvalho;
Casellas, Aina;
Bernardo, Edson;
Ruperez, Maria;
Gonzalez, Raquel;
Maculuve, Sonia;
Saura-Lázaro, Anna;
Menendez, Clara;
Naniche, Denise;
Lopez-Varela, Elisa.
Background: There are 170,000 children living with HIV in 2017 in Mozambique. Scaling-up HIV care requires effective retention along the cascade. We sought to evaluate the pediatric cascade in HIV care at the Manhiça District Hospital. Methods: A prospective cohort of children <15 years was followed fro...
Fuente-Soro, Laura;
Lopez-Varela, Elisa;
Augusto, Orvalho;
Sacoor, Charfudin;
Nhacolo, Ariel;
Nhacolo, Ariel;
Honwana, Nely;
Karajeanes, Esmeralda;
Vaz, Paula;
Naniche, Denise.
This analysis was nested in a prospective cohort established in southern Mozambique which conducted three HIV-testing modalities: voluntary counselling and testing (VCT), provider-initiated counselling and testing (PICT) and home-based testing (HBT). Participants were given the opportunity to self-report...
Gonzalez, Raquel;
Ruperez, , Marı´a;
Sevene, Esperanc¸a;
Vala, Anifa;
Maculuve, So´nia;
Bulo, Helder;
Nhacolo, Arse´nio;
Mayor, Alfredo;
Aponte, John J;
Macete, Euse´bio;
Medenendez, Clara.
The HIV epidemic is concentrated in sub-Saharan Africa. However, limited information exists on its impact on women and infant's health since the introduction of antiretroviral drugs in this region, where health resources are often scarce.
Methods: The effect of HIV infection on maternal health, birth ou...
Anti-HIV Agents/therapeutic use,
HIV Infections/therapy,
HIV Infections/epidemiology,
Maternal Mortality,
Infant, Newborn,
Parturition,
d0000680970,
Pregnancy Complications, Infectious/therapy,
Pregnancy Complications, Infectious/epidemiology,
Pregnancy Outcome/epidemiology,
Prospective Studies,
Mozambique
Ukah, U Vivian;
Mbofana , Francisco;
Rocha, Beatriz Manriquez;
Loquiha, Osvaldo;
Mudenyanga, Chishamiso;
Usta, Momade;
Urso, Marilena;
Drebit, Sharla;
Magee, Laura A;
Dadelszen, Peter von.
In well-resourced settings, reduced circulating maternal-free placental growth factor (PlGF) aids in either predicting or confirming the diagnosis of preeclampsia, fetal growth restriction, stillbirth, preterm birth, and delivery within 14 days of testing when preeclampsia is suspected. This blinded, pro...
Mozambique/epidemiology,
Pre-Eclampsia/blood,
Prospective Studies,
ddcs0347820,
d0017240,
d0109490,
d0072300,
Gestational Age,
Placenta Growth Factor/blood,
Pre-Eclampsia/diagnosis,
Pre-Eclampsia/epidemiology,
Prenatal Care/statistics & numerical data,
Survival Rate/trends
Tint, Halidou;
Seveno, Esperança;
Dellicour, Stephanie;
Calip, Gregory S;
D'Alessandro, Umberto;
Macete, Eusébio;
Diallo , Seydou Nakanabo;
Kazienga, Adama;
Valea, Innocent;
Sorgho, Hermann;
Valá, Anifa;
Augusto, Orvalho;
Ruperez, Clara;
Menendez, Clara;
Ouma, Peter;
Desai, Meghna;
Kuile, Feiko Ter;
Stergachis, Andy.
Background: A major unresolved safety concern for malaria case management is the use of artemisinin combination therapies (ACTs) in the first trimester of pregnancy. There is a need for human data to inform policy makers and treatment guidelines on the safety of artemisinin combination therapies (ACT) wh...
Antimalarials/adverse effects,
Artemisinins/adverse effects,
Clinical Protocols,
Cohort Studies,
Drug Administration Schedule,
Gestational Age,
Malaria/therapy,
Maternal-Fetal Exchange,
Patient Selection,
Pharmacovigilance,
Pregnancy Complications, Parasitic/therapy,
Pregnancy Outcome,
Pregnancy Trimester, First,
Prenatal Exposure Delayed Effects,
Prospective Studies,
Research Design,
Sample Size,
Mozambique,
Burkina Faso,
Kenya,
Antimalarials/therapeutic use,
Artemisinins/therapeutic use
Maixenchs, maria;
Boene, helena;
Anselmo, rui;
Mindu, carolina;
Alonso, pedro;
Menéndez, clara;
Macete, Eusébio;
Pool, robert;
Letang, emílio;
Naniche, denise;
Munguambe, khátia.
Objective: The objective of this qualitative study was to explore how clinical symptoms may affect adherence to antiretroviral therapy (ART) in HIV patients, and to explore factors, perceptions and attitudes related to adherence to therapy.
Design: A qualitative study was carried out in the context of th...
Anti-Retroviral Agents/adverse effects,
Anti-Retroviral Agents/therapeutic use,
Antiretroviral Therapy, Highly Active/adverse effects,
Family Characteristics,
HIV/drug effects,
HIV Infections/drug therapy,
HIV Infections/epidemiology,
Hospitals, Rural,
Medication Adherence,
Prospective Studies,
Qualitative Research,
Socioeconomic Factors,
Mozambique/epidemiology
Schacht, Caroline De;
Mabunda, Nédio;
Jr, Orlando C Ferreira;
Ismael, Nália;
Calú, Nurbai;
Santos, Iolanda;
Hoffman, Heather J;
Alons, Catharina;
Guay, Laura;
Jani, Ilesh V.
Introduction: Acute infection with HIV in the postpartum period results in a high risk of vertical transmission through breastfeeding. A study was done to determine the HIV incidence rate and associated risk factors among postpartum women in Southern Mozambique, where HIV prevalence among pregnant women ...
