Background: Opt-out HIV testing is offered at 70% of antenatal care (ANC) clinics in Mozambique through the
prevention of mother-to-child transmission (PMTCT) program. If routine data from this program were of sufficient
quality, their heightened coverage and continuous availability could complement or e...
HIV Infections/diagnosis,
HIV Infections/epidemiology,
HIV Infections/prevention & control,
Infectious Disease Transmission, Vertical/prevention & control,
Infectious Disease Transmission, Vertical/statistics & numerical data,
Mozambique/epidemiology,
Pregnancy Complications, Infectious/diagnosis,
Pregnancy Complications, Infectious/epidemiology,
Pregnancy Complications, Infectious/prevention & control,
Pregnancy Complications, Infectious/virology,
Prevalence,
Sentinel Surveillance
As infecções pelo Plasmodium falciparum (P.falciparum) e pelo Vírus da Imunodeficiência Humana (HIV) constituem problema de Saúde Pública particularmente na África subsaariana onde as duas infecções têm o seu maior peso. A sobreposição geográfica das duas infecções implica a ocorrência da...
Plasmodium falciparum,
HIV Infections,
Malaria/complications,
Malaria/diagnosis,
Patients,
T-Lymphocytopenia, Idiopathic CD4-Positive,
Genetic Variation,
Merozoites,
Mozambique,
Antimalarials/immunology,
CD4 Antigens
HIV proviral DNA integration into the host chromosome is carried out by integrase becoming an important arget antiretroviral therapy. Raltegravir was the first integrase inhibitor approved for use in HIV therapy andelvitegravir is in the late phase of clinical development; both show good results in monot...
DNA, Viral/chemistry,
DNA, Viral/genetics,
Drug Resistance, Viral,
Genetic Variation,
HIV Infections/virology,
HIV Integrase/genetics,
HIV Integrase Inhibitors/therapeutic use,
Molecular Sequence Data,
Proviruses/genetics,
Mutation, Missense,
Mozambique/epidemiology,
Sequence Analysis, DNA/instrumentation
The scale-up of effective HIV viral load (VL) testing is an urgent public health priority. Implementation of testing
is supported by the availability of accurate, nucleic acid based laboratory and point-of-care (POC) VL technologies and strong
WHO guidance recommending routine testing to identify treatme...
Background: The prevalence of hepatitis B virus (HBV) infection and human immunodeficiency virus (HIV) infection in Mozambique is one of the highest in the world, though in spite of this the prevalence of occult hepatitis B infection (OBI) is unknown.
Objectives: This study was conducted with the aim to ...
Anti-HIV Agents/therapeutic use,
DNA, Viral/genetics,
HIV Infections/complications,
Hepatitis B/complications,
Hepatitis B/diagnosis,
Hepatitis B virus/genetics,
Mozambique,
Hepatitis B virus/isolation & purification,
d0065140,
Viral Load
Chambal, Lúcia Mabalane;
Gudo, Eduardo Samo;
Carimo, Awa;
Real, Rita Corte;
Mabunda, Nédio;
Maueia, Cremildo;
Vubil, Adolfo;
Zicai, Ana Flora;
Bhatt, Nilesh;
Antunes, Francisco.
Background HIV/ HBVcoinfected patients are at high risk of developing chronic HBV infection, liver cir rhosis and hepatocellular carcinoma. In Mozambique, where HIV prevalence is one of the highest in the world, HIV-infected patients are scarcely characterized in terms of HBV coin fection and 3TC-resista...
d0065280,
Hepatitis B virus/genetics,
HIV Infections/blood,
HIV Infections/virology,
HIV Infections/complications,
Coinfection/epidemiology,
Hepatitis B, Chronic/complications,
Hepatitis B, Chronic/virology,
Mutation,
Mozambique
Bila, Dulce Celina Adolfo;
Young, Pedro;
Merks, Harriet;
Vubil, Adolfo Salvador;
Mahomed, Mussagy;
Augusto, Angelo;
Abreu, Celina Monteiro;
Mabunda, Nédio Jonas;
Brooks, James, I;
Tanuri, Amilcar;
Jani, Ilesh Vinodrai.
Objective: InMozambique, highly active antiretroviral treatment (HAART) was introduced in 2004 followed by decentralizationandexpansion, resulting inamorethan20-fold increase incoverageby2009. ImplementationofHIV drugresistancethresholdsurveys (HIVDR-TS) iscrucial inorder tomonitor theemergenceof transmi...
Anti-HIV Agents/pharmacology,
Anti-HIV Agents/therapeutic use,
Antiretroviral Therapy, Highly Active,
Mozambique,
Drug Resistance, Viral/genetics,
HIV Infections/therapy,
HIV Infections/epidemiology,
HIV Infections/virology,
HIV-1/classification,
HIV-1/radiation effects,
HIV-1/genetics,
Mozambique/epidemiology,
Mutation,
Phylogeny
Bergeron, michèle;
Daneau, géraldine;
Ding, tao;
Sitoe, Nádia;
Westerman, larry, e;
Stokx, jocelijn;
Jani, ilesh, v;
Coetzee, lindi, m;
Scott, lesley;
Weggheleire, anja de;
Boel, Luc;
Stevens, wendy, s;
Glencross, deborah;
Peter, trevor, f.
Introduction: Point-of-care (POC) CD4 testing can improve access to treatment by enabling decentralization and reducing patient loss-to-follow-up. As new POC CD4 technologies become available, their performance should be assessed before widespread deployment. This study reports the findings of five indep...
Objectives: To compare HIV care quality provided by non-physician clinicians (NPC) and physicians.
Design: Retrospective cohort study assessing the relationship between provider cadre and HIV care quality among non-pregnant adult patients initiating antiretroviral therapy (ART) in the national HIV care ...
Schito, Marco;
Peter, Trevor F;
Cavanaugh, Sean;
Piatek, Amy S;
Young, Gloria J;
Alexander, Heather;
Coggin, William;
Domingo, Gonzalo J;
Ellenberger, Dennis;
Ermantraut, Eugen;
Jani, Ilesh V;
Katamba, Achilles;
Palamountain, Kara M;
Essajee, Shaffiq;
Dowdy, David W.
Stakeholders agree that supporting high-quality diagnostics is essential if we are to continue to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis. Despite the need to strengthen existing laboratory infrastructure, which includes expanding and developing new laborator...
HIV Infections/diagnosis,
Quality Assurance, Health Care/economics,
Tuberculosis/diagnosis,
Quality Assurance, Health Care/methods,
Point-of-Care Systems/economics,
Bacteriological Techniques/economics,
Bacteriological Techniques/methods,
Laboratories,
Virology/methods,
Virology/economics
