Mozambique is facing two great adversaries. One is COVID-19 that claimed 132
confirmed deaths and 15,866 infections in its first round since the first case recorded
on 22 March 2020 until 2 December 2020 [1]. The second is the armed conflicts
in the Northern region of Mozambique perpetrated by armed f...
Bezerra, Ohanna Cavalcanti de Lima;
Arnez, Lucia Elena Alvarado;
Mabunda, Nedio;
Salomé, Graça;
Sousa, Amina de;
Kehdy, Fernanda de Souza Gomes;
Marques, Carolinne Sales;
Manta, Fernanda Saloum de Neves;
Andrade, Rafaela Mota;
Ferreira, Lais Pereira;
Calvo, Thyago Leal;
Cardoso, Cynthia Chester;
Nunes, Kelly;
Gouveia, Matheus H;
Mbulaiteve, Sam M;
Yeboah, Edward D;
Hsing, Ann;
Latini, Ana Carla Pereira;
Leturiondo, André Luiz;
Rodrigues, Fabiola da Costa;
Noronha, Ariani Batista;
Ferreira, Cinthia de Oliveira;
Talhari, Carolina;
Rêgo, Jamile Leão;
Castellucci, Léa Cristina de Carvalho;
Terazona-Santos, Eduardo;
Carvalho, Elizeu Fagundes de;
Meyer, Diogo;
Pinheiro, Roberta Olmo;
Jani, Ilesh V;
Pacheco, Antonio Guilherme;
Moraes, Milton Ozório.
Investigation of human genes under pathogen-driven selection as Plasmodium sp. has pinpointed genetic variants that participate in the adaptation to the environment and/or are related to severities of human diseases. The current study examined an example of an evolutionary trade-off in which genetic vari...
Izco, Santiago;
Murias-Closas, Adrià;
Jordan, Alexander M;
Greene, Gregory;
Catorze, Nteruma;
Chiconela, Helio;
Garcia, Juan Ignacio;
Blanco-Arevalo, Alejandro;
Febrer, Anna;
Casellas, Aina;
Saavedra, Belén;
Chiller, Tom;
Nhampossa, Tacilta;
Garcia-Basteiro, Alberto;
Letang, Emilio.
Introduction: AIDS-mortality remains unacceptably high in sub-Saharan Africa, largely driven by advanced HIV disease (AHD). We nested a study in an existing tuberculosis (TB) contact-tracing intervention (Xpatial-TB). The aim was to assess the burden of AHD among high-risk people living with HIV (PLHIV) ...
Kenga, Darlenne B;
Gebretsadik, Tebeb;
Simbine, Samuel;
Simbine, Samuel;
Maússe, Fabião E;
Charles, Pedro;
Zaqueu, Ernesto;
Fernando, Hermenegilda F;
Sacarlal, Jahit;
Moon, Troy D.
Background: Bacteremia is a major cause of morbidity and mortality worldwide. Children infected with HIV present with patterns of bacteremia generally associated with poor prognosis. In Mozambique, data on bacteremia are sparce.
Methods: We conducted an observational study of HIV-infected and HIV-expose...
Anti-Bacterial Agents/therapeutic use,
Bacteremia/epidemiology,
Bacteremia/drug therapy,
Community-Acquired Infections/drug therapy,
Community-Acquired Infections/epidemiology,
Fever/drug therapy,
HIV Infections/epidemiology,
HIV Infections/complications,
HIV Infections/drug therapy,
Microbial Sensitivity Tests,
Staphylococcal Infections/drug therapy,
Mozambique/epidemiology
Mayor, Alfredo;
Silva, Clemente;
Valbona, Eduard Rovira;
Feltrer, Arantxa Roca;
Bonnington, Craig;
Smith, Alexandra Wharton;
Greehouse, Bryan;
Bever, Caitlin;
Chidimatembue, Arlindo;
Guinovart, Caterina;
Proctor, Joshua L;
Rodrigues, Maria;
Canana, Neide;
Arnaldo, Paulo;
Boene, Simone;
Enosse, Sonia;
Saute, Francisco;
Candrinho, Baltazar.
Introduction: Genomic data constitute a valuable adjunct to routine surveillance that can guide programmatic decisions to reduce the burden of infectious diseases. However, genomic capacities remain low in Africa. This study aims to operationalise a functional malaria molecular surveillance system in Moz...
Sevene, Esperança;
Boene, Helena;
Vidler, Marianne;
Valá, Anifa;
Macuacua, Salésio;
Augusto, Orvalho;
Fernandes, Quinhas;
Macete, Eusébio;
Sidat, Mohsin;
Dadelszen, Peter von;
Munguambe, Khátia;
Bique, Cassimo.
Background
Maternal mortality is an important public health problem in low-income countries. Delays in reaching health facilities and insufficient health care professionals call for innovative community-level solutions. There is limited evidence on the role of community health workers in the management o...
Clinical Competence,
Community Health Services/standards,
Community Health Workers/psychology,
Disease Management,
Emergency Treatment/standards,
Feasibility Studies,
Health Knowledge, Attitudes, Practice,
Maternal Mortality,
Patient Acceptance of Health Care,
Pre-Eclampsia/diagnosis,
Pre-Eclampsia/therapy,
Prenatal Care,
Referral and Consultation,
Mozambique
Soler, Helena Marti;
Máquina, Mara;
Opiyo, Mercy;
Alafo, Celso;
Smith, Ellie Sherrard;
Malheia, Arlindo;
Cuamba 6, Nelson;
Sacoor, Charfudin;
Rabinovich, Niquice;
Aide, Pedro;
Saúte, Francisco;
Paaijmans, Krijn.
Indoor residual spraying (IRS) is one of the main malaria vector control strategies in Mozambique alongside the distribution of insecticide treated nets. As part of the national insecticide resistance management strategy, Mozambique introduced SumiShield™ 50WG, a third generation IRS product, in 2018. ...
Interrupted time-series (ITS) designs are a robust and increasingly popular nonrandomized study design for strong causal inference in the evaluation of public health interventions. One of the most common techniques for model parameterization in the analysis of ITS designs is segmented regression, which u...
Altered mental status (AMS) is a priority presenting sign that must be assessed in HIV-infected, febrile children, yet diagnosis is difficult in areas with limited diagnostic capacity. Malaria and bacterial meningitis have been reported as the most common causes of AMS in febrile children presenting to t...
Advancements in global mental health implementation research have revealed promising strategies for improving access to evidence-based mental health care. These advancements have not translated, however, into a reduced prevalence of mental disorders. In this review we examine the relationships between de...
