Schito, Marco Schito;
Cavanaugh, Sean;
Piatek, Amy S;
Young, Gloria J;
Alexander, Heather;
Coggin, William;
Domingo, Gonzalo J;
Ellenberger, Denny;
Ermantraut, Eugen;
Jani, Ilesh V;
Katamba, Achilles;
Palamoutain, Kara M;
Essajee, Shaffiq;
Dowdy, David W;
Peter, Trevor F.
Stakeholders agree that supporting high-quality diagnostics is essential if we are to continue to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis. Despite the need to strengthen existing laboratory infrastructure, which includes expanding and developing new laborator...
Lahuerta, Maria;
Lima, Josue;
Biribonwoha, Harriet Nuwagaba;
Okamura, Mie;
Alvim, Maria Fernanda;
Fernandes, Rufino;
Assan, Americo;
Hoos, David;
Elul, Batya;
El-Sadr, Wafaa M;
Nash, Denis.
Despite recent changes to expand the ART eligibility criteria in sub-Saharan Africa, many patients still initiate ART in the advanced stages of HIV infection, which contributes to increased early mortality rates, poor patient outcomes, and onward transmission. To evaluate individual and clinic-level fact...
Jani, Ilesh;
Sebastian, Jennifer;
Vubil, Adolfo;
Subbarao, Shambavi;
Bila, Dolce;
Sousa, Amina;
Mabunda, Nédio;
Garcia, Albert;
Ellemberger, Dennis;
Ramos, Artur;
Skaggs, Beth.
We performed a comparative analysis between Roche Amplicor HIV-1 DNA test and CAPTAQ assay for the detection of HIV in 830 dried blood spot (DBS) pediatric samples collected in Mozambique. Our results demonstrated no statistical difference between these assays. The CAPTAQ assay approached nearly 100% rep...
Lambdin, Barrot H;
Micek, Mark A;
Koepsell, Thomas D;
Hughes, James P;
Sherr, Kenneth;
Pfeiffer, James;
Karagianis, Marina;
Lara, Joseph;
Gloyd, Stephen S;
Stergachis, Andy.
Since the rapid scale-up of antiretroviral therapy (ART) programs in sub-Saharan Africa, electronic patient tracking systems (EPTS) have been deployed to respond to the growing demand for program monitoring, evaluation and reporting to governments and donors. These routinely collected data are often used...
Ambulatory Care Information Systems/standards,
Anti-HIV Agents/therapeutic use,
CD4 Lymphocyte Count,
Cross-Sectional Studies,
Electronic Health Records/standards,
HIV Infections/drug therapy,
Mozambique,
Outcome Assessment, Health Care/methods,
Reproducibility of Results,
Severity of Illness Index
“Experiências e percepções sobre o uso de insumos de prevenção do HIV e outras ITS em homens que fazem sexo com homens" é um estudo que foi realizado na cidade de Maputo no período entre 2010 - 2012. A motivação do mesmo surgiu no âmbito duma investigação sobre avaliação de risco e vulner...
Sexual Behavior,
Knowledge,
Spouses,
Sexually Transmitted Diseases,
Health Strategies,
HIV,
Infections,
HIV Infections,
Sexual and Gender Minorities,
Disease Prevention,
Sexual and Gender Minorities
Oliveira, Michelli, F;
Ramalho, Dulce, B;
Abreu, Celina, M;
Vubil, Adolfo Salvador;
Mabunda, Nédio;
Ismael, Nalia;
Francisco, Cidia;
Jani, Ilesh, V;
Tanuri, Amilcar.
HIV proviral DNA integration into the host chromosome is carried out by integrase becoming an important target antiretroviral therapy. Raltegravir was the first integrase inhibitor approved for use in HIV therapy and elvitegravir is in the late phase of clinical development; both show good results in mon...
DNA, Viral/genetics,
HIV-1,
DNA, Viral/chemistry,
Mozambique,
Drug Resistance, Viral,
Genetic Variation,
HIV Infections/virology,
HIV Integrase/genetics,
Molecular Sequence Data,
Mutation,
Proviruses/genetics,
Sequence Analysis, DNA
HIV prevalence rates in Zambézia Province were estimated to be 12.6% in 2009. A number of educational campaigns have been aimed at improving HIV transmission and prevention knowledge among community members in an effort to reduce infection rates. These campaigns have also encouraged people to seek healt...
Anti-HIV Agents/therapeutic use,
Mozambique/epidemiology,
Africa,
Residence Characteristics,
Delivery of Health Care,
HIV Infections/epidemiology,
HIV Infections/psychology,
HIV Infections/therapy,
Health Knowledge, Attitudes, Practice,
Medicine, African Traditional,
Patient Acceptance of Health Care/psychology,
Patient Acceptance of Health Care/statistics & numerical data,
Rural Population/statistics & numerical data,
Sexual Partners/psychology
In 2009 there were an estimated 22.5 million individuals living
with HIV infection in sub-Saharan Africa and 1.8 million new
infections. [1] Only 37% of those living in sub-Saharan Africa who
were eligible for treatment were receiving antiretroviral therapy as
of 2009, [1] and only 54% of pregnant women ...
Vaz, paula;
Eugenia, macassa;
Jani, ilesh, v;
Thome, beatriz;
Mahagaja, epifanio;
Madede, tavares;
Muando, valeria;
Biberfeld, gunnel;
Anderson, soren;
Blanche, stephane.
AIDS-associated Kaposi sarcoma occurs in children, but treatment experience reports are very scarce. A retrospective analysis of 28 children treated with highly active antiretroviral therapy and monthly paclitaxel showed unexpected results with 19 children in complete and sustainable remission, including...
Anti-Retroviral Agents/administration & dosage,
Antineoplastic Agents/administration & dosage,
Antiretroviral Therapy, Highly Active/methods,
Drug Therapy/methods,
HIV Infections/complications,
HIV Infections/virology,
HIV-1/isolation & purification,
Sarcoma, Kaposi/therapy,
Sarcoma, Kaposi/pathology,
Treatment Outcome
Maueia, Cremildo;
Costa, Deise;
Meggi, Bindiya;
Ismael, Nalia;
Walle, Carla;
Curvo, Raphael;
Abreu, Celina;
Bhatt, Nilesh;
Tanuri, Amilcar;
Jani, Ilesh V;
Ferreira, Orlando C.
The HIV/AIDS pandemic is primarily caused by HIV-1. Another virus type, HIV-2, is found mainly in West African countries. We hypothesized that population migration and mobility in Africa may have facilitated the introduction and spreading of HIV-2 in Mozambique. The presence of HIV-2 has important implic...
Cross-Sectional Studies,
HIV Envelope Protein gp41,
HIV Antibodies,
Enzyme-Linked Immunosorbent Assay,
HIV Infections,
HIV-2,
Immunoblotting,
Incidence,
Mozambique,
Phylogeography,
Population Surveillance,
Viral Load
