Floridia, Marco;
Ciccacci, Fausto;
Andreotti, Mauro;
Hassane, Archa;
Sidumo, Zita;
Magid, Nurja A;
Sotomane, Horacio;
David, Muhlavasse;
Mutemba, Elsa;
Cebola, Junia;
Mugunhe, Remigio José;
Riccardi, Fabio;
Marazzi, Maria Cristina;
Giuliano, Marina;
Palombi, Leonardo;
Mancinelli, Sandro.
Tuberculosis is a major health concern in several countries, and effective diagnostic algorithms for use in human
immunodeficiency virus (HIV)–positive patients are urgently needed.
Methods. At prescription of antiretroviral therapy, all patients in 3 Mozambican health centers were screened for tubercu...
Algorithms,
Antiretroviral Therapy, Highly Active,
Antitubercular Agents,
HIV Infections/drug therapy,
Lipopolysaccharides,
Molecular Diagnostic Techniques,
Mozambique,
Mycobacterium tuberculosis,
Prevalence,
Sensitivity and Specificity,
Tuberculosis, Pulmonary/diagnosis,
Sputum
Peter, trevor;
Ellenberger, dennis;
Boeras, debrah;
Kim, andrea A;
Messele, tsehaynesh;
Roberts, teri;
Stevens, wendy;
Jani, ilesh;
Abimiku, alash'le;
Ford , nathan;
Katz, Zachary;
Nkengasong, john N.
Scaling up access to HIV viral load testing for individuals undergoing antiretroviral therapy in low-resource settings is a global health priority, as emphasised by research showing the benefits of suppressed viral load for the individual and the whole population. Historically, large-scale diagnostic tes...
Anti-HIV Agents/therapeutic use,
Antiretroviral Therapy, Highly Active/methods,
Drug Monitoring,
HIV Infections/drug therapy,
Health Policy,
Medical Laboratory Science,
Blood/virology,
Desiccation/methods,
Global Health,
HIV Infections/prevention & control,
HIV Infections/virology,
Medical Laboratory Science/organization & administration,
Specimen Handling/methods,
Viral Load
Context: The effect of global health initiatives on population health is uncertain. Between 2003 and 2008, the US President's Emergency Plan for AIDS Relief (PEPFAR), the largest initiative ever devoted to a single disease, operated intensively in 12 African focus countries. The initiative's effect on al...
Africa/epidemiology,
Antiviral Agents/supply & distribution,
Antiviral Agents/therapeutic use,
Federal Government,
Capacity Building,
Africa South of the Sahara/epidemiology,
HIV Infections/drug therapy,
HIV Infections/mortality,
HIV Infections/prevention & control,
International Cooperation/legislation & jurisprudence,
Health Promotion/legislation & jurisprudence
Maixenchs, maria;
Boene, helena;
Anselmo, rui;
Mindu, carolina;
Alonso, pedro;
Menéndez, clara;
Macete, Eusébio;
Pool, robert;
Letang, emílio;
Naniche, denise;
Munguambe, khátia.
Objective: The objective of this qualitative study was to explore how clinical symptoms may affect adherence to antiretroviral therapy (ART) in HIV patients, and to explore factors, perceptions and attitudes related to adherence to therapy.
Design: A qualitative study was carried out in the context of th...
Anti-Retroviral Agents/adverse effects,
Anti-Retroviral Agents/therapeutic use,
Antiretroviral Therapy, Highly Active/adverse effects,
Family Characteristics,
HIV/drug effects,
HIV Infections/drug therapy,
HIV Infections/epidemiology,
Hospitals, Rural,
Medication Adherence,
Prospective Studies,
Qualitative Research,
Socioeconomic Factors,
Mozambique/epidemiology
Rupérez, María;
Pou, Christian;
Maculuve, Sonia;
Cedeño, Samandy;
Luis, Leopoldina;
Rodríguez, Judith;
Letang, Emilio;
Moltó, José;
Macete, Eusébio;
Clotet, Boaventura;
Alonso, Pedro;
Menéndez, Clara;
Naniche, Denise;
Paredes, Roger.
Objectives: The objective of this study was to inform public health actions to limit first-line ART failure and HIV drug resistance in Mozambique.
Methods: This was a cross-sectional study. HIV-1-infected adults on first-line ART for at least 1 year attending routine visits in the Manhiça District Hospi...
Anti-Retroviral Agents/therapeutic use,
Drug Monitoring,
Drug Resistance, Viral,
Genotype,
Genotyping Techniques,
HIV Infections/drug therapy,
HIV Infections/virology,
HIV-1/genetics,
HIV-1/isolation & purification,
Suburban Population,
Treatment Failure,
Mozambique,
Drug Resistance
Viegas, Edna Omar;
Tembe, Nelson;
Macovela, Eulália;
Gonçalves, Emília;
Augusto, Orvalho;
Ismael, Nália;
Sitoe, Nádia;
Schacht, Caroline De;
Bhatt, Nilesh;
Meggi, Bindiya;
Araujo, Carolina;
Sandström, Eric;
Biberfeld, Gunnel;
Nilsson, Charlotta;
Andersson, Sören;
Jani, Ilesh;
Osman, Nafissa.
Background: Prevalence of HIV in Mozambique among individuals aged 15-49 years is 11.5%. The HIV prevalence is higher in women than in men across the country, peaking at ages 25-29 years and 35-39 years, respectively. In this study, we aimed at determining the prevalence and incidence of HIV, prevalence ...
González, Raquel;
Desai, Meghna;
Macete 3, Eusebio;
Ouma, Peter;
Kakolwa, Mwaka A;
Abdulla, Salim;
Aponte, John J;
Bulo, Helder;
Kabanywanyi, Abdunoor M;
Katana, Abraham;
Maculuve, Sonia;
Mayor, Alfredo;
Nhacolo, Arsenio;
Otieno, Kephas;
Pahlavan, Golbahar;
Rupérez, María;
Sevene, Esperança;
Slutsker, Laurence;
Vala, Anifa;
Williamsom, John;
Menéndez, Clara.
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women taking daily cotrimoxazole prophylaxis (CTXp) because of potential added risk of adve...
Antimalarials/administration & dosage,
Double-Blind Method,
Follow-Up Studies,
HIV Infections/diagnosis,
HIV Infections/drug therapy,
HIV Infections/epidemiology,
Infectious Disease Transmission, Vertical/prevention & control,
Malaria/diagnosis,
Malaria/epidemiology,
Malaria/prevention & control,
Mefloquine/administration & dosage,
Pregnancy Complications, Infectious/diagnosis,
Pregnancy Complications, Infectious/epidemiology,
Pregnancy Complications, Infectious/prevention & control,
Pregnancy Complications, Parasitic/diagnosis,
Pregnancy Complications, Parasitic/epidemiology,
Pregnancy Complications, Parasitic/prevention & control,
Pregnancy Outcome,
Mozambique/epidemiology,
Tanzania/epidemiology,
Kenya/epidemiology,
Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage
Lambdin, Barrot H;
Micek, Mark A;
Koepsell, Thomas D;
Hughes, James P;
Sherr, Kenneth;
Pfeiffer, James;
Karagianis, Marina;
Lara, Joseph;
Gloyd, Stephen S;
Stergachis, Andy.
Since the rapid scale-up of antiretroviral therapy (ART) programs in sub-Saharan Africa, electronic patient tracking systems (EPTS) have been deployed to respond to the growing demand for program monitoring, evaluation and reporting to governments and donors. These routinely collected data are often used...
Ambulatory Care Information Systems/standards,
Anti-HIV Agents/therapeutic use,
CD4 Lymphocyte Count,
Cross-Sectional Studies,
Electronic Health Records/standards,
HIV Infections/drug therapy,
Mozambique,
Outcome Assessment, Health Care/methods,
Reproducibility of Results,
Severity of Illness Index
Ismael, Nalia;
Wilkinson, Eduan;
Mahumane, Isabel;
Mahumane, Isabel;
Gemusse, Hernanane;
Giandhari, Jennifer;
Bauhofer, Adilson;
Vubil, Adolfo;
Mambo, Pirolita;
Singh, Lavanya;
Mabunda, Nédio;
Bila, Dulce;
Engelbrecht, Susan;
Gudo, Eduardo;
Lessells, Richard;
Oliveira, Túlio.
HIV drug resistance (HIVDR) can become a public health concern, especially in low- and middle-income countries where genotypic testing for people initiating antiretroviral therapy (ART) is not available. For first-line regimens to remain effective, levels of transmitted drug resistance (TDR) need to be m...
Mozambique/epidemiology,
HIV-1/genetics,
Drug Resistance, Viral/genetics,
Anti-HIV Agents/therapeutic use,
Anti-HIV Agents/pharmacology,
HIV Infections/drug therapy,
HIV Infections/epidemiology,
HIV Seropositivity,
Molecular Epidemiology,
Reverse Transcriptase Inhibitors/pharmacology,
Prevalence
