Background: Concerning gaps in the HIV care continuum compromise individual and population health. We evaluated a combination intervention strategy (CIS) targeting prevalent barriers to timely linkage and sustained retention in HIV care in Mozambique.
Methods and findings: In this cluster-randomized tria...
Anti-HIV Agents/administration & dosage,
Cluster Analysis,
Combined Modality Therapy,
Early Medical Intervention/methods,
Follow-Up Studies,
HIV Infections/diagnosis,
HIV-1/drug effects,
Health Behavior,
Motivation,
Patient Compliance,
Epidemiology,
Therapeutics,
Mozambique,
HIV Infections/therapy
Introduction: The scale-up of effective HIV viral load (VL) testing is an urgent public health priority. Implementation of testing is supported by the availability of accurate, nucleic acid based laboratory and point-of-care (POC) VL technologies and strong WHO guidance recommending routine testing to id...
Chang, joy;
Sousa, amina de;
Sabatier, jennifer;
Assane, mariamo;
Zhang, guoqing;
Bila, dulce;
Vaz, paula;
Alfredo, charity;
Cossa, Loide;
Bhatt, Nilesh;
Koumans, emilia, h;
Yang, chunfu;
Rivadeneira, emilia;
Jani, ilesh;
Houston, james, c.
Quantitative plasma viral load (VL) at 1000 copies /mL was recommended as the threshold to confirm antiretroviral therapy (ART) failure by the World Health Organization (WHO). Because of ongoing challenges of using plasma for VL testing in resource-limited settings (RLS), especially for children, this st...
Decroo, Tom;
Telfer, Bárbara;
Dores, Carla Das;
Branco, Ricardo A;
Santos, Natacha Dos;
Mkwamba, Alec;
Dezembro, Sergio;
Joffrisse, Mariano;
Ellman, Tom;
Metcalf , Carol.
Objectives
Estimate the effect of participation in Community ART Groups (CAG) versus individual care on retention-in-care (RIC) on antiretroviral therapy (ART).
Design
Retrospective cohort study.
Setting
High levels of attrition (death or loss-to-follow-up (LTFU) combined) on ART indicate that delivery...
Gonzalez, Raquel;
Ruperez, , Marı´a;
Sevene, Esperanc¸a;
Vala, Anifa;
Maculuve, So´nia;
Bulo, Helder;
Nhacolo, Arse´nio;
Mayor, Alfredo;
Aponte, John J;
Macete, Euse´bio;
Medenendez, Clara.
The HIV epidemic is concentrated in sub-Saharan Africa. However, limited information exists on its impact on women and infant's health since the introduction of antiretroviral drugs in this region, where health resources are often scarce.
Methods: The effect of HIV infection on maternal health, birth ou...
Anti-HIV Agents/therapeutic use,
HIV Infections/therapy,
HIV Infections/epidemiology,
Maternal Mortality,
Infant, Newborn,
Parturition,
d0000680970,
Pregnancy Complications, Infectious/therapy,
Pregnancy Complications, Infectious/epidemiology,
Pregnancy Outcome/epidemiology,
Prospective Studies,
Mozambique
Background
Studies have been conducted in developing countries using SMS to communicate with patients to reduce the number of missed appointments and improve retention in treatment, however; very few have been scaled up. One possible reason for this could be that patients or staff are dissatisfied with t...
Meggi, Bindiya;
Bollinger, Timothy;
Mabunda, Nédio;
Vubil, Adolfo;
Tobaiwa, Ocean;
Quevedo, Jorge I;
Loquiha, Osvaldo;
Vojnov, Lara;
Peter, Trevor F;
Jani, Ilesh V.
The long delay in returning test results during early infant diagnosis of HIV (EID) often
causes loss-to-follow-up prior to antiretroviral treatment (ART) initiation in resource-limited
settings. A point-of-care (POC) test may help overcome these challenges. We evaluated
the performance of the LYNX p24 A...
Anti-HIV Agents/therapeutic use,
Early Diagnosis,
HIV Infections/diagnosis,
HIV Infections/therapy,
HIV Infections/epidemiology,
HIV Infections/immunology,
Point-of-Care Testing/standards,
Reproducibility of Results,
Mozambique/epidemiology,
Sensitivity and Specificity,
HIV-1/immunology
Studies have been conducted in developing countries using SMS to communicate with patients to reduce the number of missed appointments and improve retention in treatment, however; very few have been scaled up. One possible reason for this could be that patients or staff are dissatisfied with the method i...
Mozambique/epidemiology,
Anti-Retroviral Agents/therapeutic use,
Antitubercular Agents/therapeutic use,
HIV Infections/therapy,
HIV Infections/epidemiology,
Reminder Systems,
Telemedicine/methods,
Text Messaging,
HIV,
Health Education,
Communication,
Supply
Jani, ilesh, v;
Meggi, bindiya;
Vubil, adolfo;
Bhatt, nilesh;
Tobaiwa, ocean;
Quevedo, jorge, i;
Loquiha, osvaldo;
Lehe, jonathan, d;
Vojnov, lara;
Peter, trevor, f.
Viral load testing is the WHO-recommended monitoring assay for patients on HIV antiretroviral therapy (ART). Point-of-care (POC) assays may help improve access to viral load testing in resource-limited settings. We compared the performance of the Alere Q NAT POC viral load technology (Alere Technologies,...
Introduction—The rapid scale-up of HIV care and treatment in resource-limited countries
requires concurrent, rapid development of health information systems to support quality service
delivery. Mozambique, a country with an 11.5% prevalence of HIV, has developed nation-wide
patient monitoring systems (...
Aptitude,
Delivery of Health Care,
d0062680,
Outcome Assessment, Health Care,
d0062950,
d0590120,
HIV-1/isolation & purification,
d0630050,
HIV Infections/therapy,
Monitoring, Physiologic/methods
