In public health epidemiology, quasi-experimental methods are widely used to estimate the causal impacts of interventions. In this paper, we demonstrate the contribution the synthetic control method (SCM) can make in evaluating public health interventions, when routine surveillance data are available and...
Bezerra, Ohanna Cavalcanti de Lima;
Arnez, Lucia Elena Alvarado;
Mabunda, Nedio;
Salomé, Graça;
Sousa, Amina de;
Kehdy, Fernanda de Souza Gomes;
Marques, Carolinne Sales;
Manta, Fernanda Saloum de Neves;
Andrade, Rafaela Mota;
Ferreira, Lais Pereira;
Calvo, Thyago Leal;
Cardoso, Cynthia Chester;
Nunes, Kelly;
Gouveia, Matheus H;
Mbulaiteve, Sam M;
Yeboah, Edward D;
Hsing, Ann;
Latini, Ana Carla Pereira;
Leturiondo, André Luiz;
Rodrigues, Fabiola da Costa;
Noronha, Ariani Batista;
Ferreira, Cinthia de Oliveira;
Talhari, Carolina;
Rêgo, Jamile Leão;
Castellucci, Léa Cristina de Carvalho;
Terazona-Santos, Eduardo;
Carvalho, Elizeu Fagundes de;
Meyer, Diogo;
Pinheiro, Roberta Olmo;
Jani, Ilesh V;
Pacheco, Antonio Guilherme;
Moraes, Milton Ozório.
Investigation of human genes under pathogen-driven selection as Plasmodium sp. has pinpointed genetic variants that participate in the adaptation to the environment and/or are related to severities of human diseases. The current study examined an example of an evolutionary trade-off in which genetic vari...
Mayor, Alfredo;
Silva, Clemente;
Valbona, Eduard Rovira;
Feltrer, Arantxa Roca;
Bonnington, Craig;
Smith, Alexandra Wharton;
Greehouse, Bryan;
Bever, Caitlin;
Chidimatembue, Arlindo;
Guinovart, Caterina;
Proctor, Joshua L;
Rodrigues, Maria;
Canana, Neide;
Arnaldo, Paulo;
Boene, Simone;
Enosse, Sonia;
Saute, Francisco;
Candrinho, Baltazar.
Introduction: Genomic data constitute a valuable adjunct to routine surveillance that can guide programmatic decisions to reduce the burden of infectious diseases. However, genomic capacities remain low in Africa. This study aims to operationalise a functional malaria molecular surveillance system in Moz...
Altered mental status (AMS) is a priority presenting sign that must be assessed in HIV-infected, febrile children, yet diagnosis is difficult in areas with limited diagnostic capacity. Malaria and bacterial meningitis have been reported as the most common causes of AMS in febrile children presenting to t...
Alonso, Selena;
Vidal, Marta;
Olalla, Gemma Ruiz;
Gonzalez, Raquel;
Jairoce, Chenjerai;
Manaca, M Nelia;
Santiago, Miquel Vázquez;
Balcells, Reyes;
Vala, Anifa;
Ruperez, María;
Cistero, Pau;
Soro, Laura Fuente;
Angov, Evelina 5;
Coppel, Ross L 6;
Geimain, Benoit;
Cavanagh, David;
Beeson, James G;
Nhacolo, Arsenio;
Sevene, Esperança;
Aponte, John J;
Macete, Eusébio;
Aguilar, Ruth;
Mayor, Alfredo;
Menendez, Clara;
Dobano, Carlota;
Moncunill, Gemma.
Maternal Plasmodium falciparum-specific antibodies may contribute to protect infants against severe malaria. Our main objective was to evaluate the impact of maternal HIV infection and placental malaria on the cord blood levels and efficiency of placental transfer of IgG and IgG subclasses.
Methods: In ...
Since the announcement of the coronavirus disease (COVID-19) pandemic in January 30th 2020, 68 countries reported to the World Health Organization that they were experiencing disruptions in malaria diagnosis and treatment. This situation had the potential to lead to delays in diagnosis and treatment, whi...
Alonso, Selena;
Vudal, Marta;
Olalla, Gemma Ruiz;
Gonzelez, Raquel;
Manaca, M. Nelia;
Jairoce, Chenjerai;
Santiago, Chenjerai;
Balcells, Reyes;
Vala, Anifa;
Ruperez, María;
Cistero, Pau;
Soro, Laura Fuente;
Cova, Marta;
Angov, Evelina;
Nhacolo, Arsenio;
Sevene, Esperança;
Aponte, John J;
Macete, Eusebio;
Aguilar, Ruth;
Mayor, Alfredo;
Menendez, Clara;
Dobano, Carlota;
Moncunil, Gemma.
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...
HIV,
Immunoglobulin G,
Antibodies, Monoclonal,
Malaria,
Schools, Nursery,
Blood-Borne Pathogens,
d0053120,
Placenta/immunology,
Placenta/metabolism,
Pregnancy,
HIV Infections/virology
Background: It is frequently said that funding is essential to ensure optimal results from a malaria intervention control. However, in recent years, the capacity of the government of Mozambique to sustain the operational cost of indoor residual spraying (IRS) is facing numerous challenges due to restrict...
A malária é um dos maiores problemas de saúde pública em Moçambique e uma
das principais causas de procura dos serviços de saúde. O Plasmodium falciparumé o parasita
mais frequente, sendo responsável por mais de 90 % de todas as infecções. Nos últimos anos a taxa de
incidência por malá...
Epidemiology,
Health Centers,
Disease,
Hospitals,
Hospitals, Rural,
Malaria,
Medicine,
Mortality,
Plasmodium,
Health,
Public Health,
Mozambique
Globalmente, a crise sócio-económica desencadeada pela pandemia da CVID-19 constitui um risco gravi ao estado nutricional e de sobrevivência de criaças de países de baixa e média renda. 1No contexto actual da pandemia espera-se que haja um aumento na desnutrição infantil devido a factores diverco...
Infant Mortality/trends,
Child Nutrition Disorders/prevention & control,
Breast Feeding,
COVID-19,
Health Services Accessibility,
Anemia/diagnosis,
Maternal Mortality/trends,
Mozambique,
Postnatal Care,
Vaccines/immunology,
Infant, Premature,
Asphyxia Neonatorum,
Neonatal Sepsis,
Pneumonia,
Malaria,
Postpartum Hemorrhage
