Macete, Eusébio V;
Sacarlal, Jahit;
Aponte, John J;
Leach, Amanda;
Navia, Margarita M;
Milman, Jessica;
Guinovart, Caterina;
Mandomando, Inácio;
López-Púa, Yolanda;
Lievens, Marc;
Ofori, Alex Owusu;
Dubois, Marie-Claude;
Cahill, Conor P;
Koutsoukos, Marguerite;
Sillman, Marla;
Thompson, Ricardo;
Dubovsky, Filip;
Ballou, W Ripley;
Cohen, Joe;
Alonso, Pedro L.
Results: Both vaccines were safe and had similar reactogenicity profiles. All subjects with paired pre and post-vaccination
samples showed a vaccine response with respect to anti-circumsporozoite (CS) antibodies irrespective of initial anti-CS
serostatus. Geometric mean titers (GMTs) were 191 EU/ml (95...
Macete, E;
Aponte, J. J;
Guinovart, C;
Sacarlal, J;
Ofori-Anyinam, O;
Mandomando, I;
Espasa, M;
Bevilacqua, C;
Leach, A;
Dubois, M C;
Heppner, D G;
Tello, L;
Milman, J;
Cohen, J;
Dubovsky, F;
Tornieporth, N;
Thompson, R;
Alonso, P. L.
The development of a malaria vaccine remains a public health priority for sub-Saharan Africa. RTS,S/AS02A candidate malaria vaccine has been shown to be safe and immunogenic in previous studies in adults and staggered dose-escalation studies in children in The Gambia. However, genetic features and the in...
Sharp, brian l;
Kleinschmidt, immo;
Streat, elisabeth;
Maharaj, rajendra;
Barnes, karen i;
Durrheim, david n;
Ridl, frances c;
Morris, natasha;
Seocharan, ishen;
Kunene, simon;
Grange, jacobus j p la;
Mthembu, jotham d;
Maartens, francois;
Martin, carrin l;
Barreto, avertino.
International Cooperation,
Insect Vectors,
Eswatini/epidemiology,
Child, Preschool,
Antimalarials/therapeutic use,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/prevention & control,
Mosquito Control/methods,
Mozambique/epidemiology,
Plasmodium falciparum/isolation & purification,
Prevalence,
South Africa/epidemiology,
Time Factors
Em 1997, data do último censo, a população moçambicana era em número de 16.099.246 habitantes. Segundo as estimativas do Instituto Nacional de Estatística em Moçambique (INE) referente a 2005, a população moçambicana é de 19.420.036 habitantes. Moçambique situa-se na faixa sul-oriental do Con...
In Mozambique most of demographic data are obtained using census or sample survey including indirect estimations. A method of collecting longitudinal demographic data was introduced in southern Mozambique since 1996 (DSS -Demographic Surveillance System in Manhiça district, Maputo province), but the ext...
Objective: To describe attitudes to the expanded programme on immunization (EPI) and intermittent preventive treatment in infants (IPTi), and perceptions of the relationship between them. In particular, whether the introduction of IPTi negatively affects community attitudes to, or use of, EPI; or, conver...
Health Knowledge, Attitudes, Practice,
Caregivers/psychology,
Delivery of Health Care/methods,
Delivery of Health Care/organization & administration,
Hematologic Tests/psychology,
Immunization/psychology,
Malaria Vaccines/therapeutic use,
Immunization Programs/organization & administration,
Malaria, Falciparum/psychology,
Patient Acceptance of Health Care/psychology,
Mozambique/epidemiology
Quinto, llorenç;
Aponte, joão J;
Menéndez, clara;
Sacarlal, jahit;
Assessor, pedro;
Espasa, mateus;
Mandomando, inácio;
Guinovart, caterina;
Macete, Eusébio;
Hirt, rosmarie;
Urassa, honorathy;
Navia, margarita M;
Alonso, pedro L;
Thompson, ricardo.
Introduction: Anaemia is the most frequent haematological disorder in childhood. The notion that defines naemia does not change throughout life, although parameters used for its evaluation show significant variations during childhood. Haematocrit (Hct) (%) is usually defined as three times the value of h...
Valles, Xavier;
Flannery, Brendan;
Roca, Anna;
Mandomando, Inacio;
Sigauque, Betuel;
Sanz, Sergi;
Schuchat, Anne;
Levine, Myron;
Soriano-Gabarro, Montserrat;
Alonso, Pedro.
Objective: To describe and compare serotype distribution and antibiotic susceptibility of invasive and nasopharyngeal isolates of Streptococcus pneumoniae from children in rural Mozambique. Methods: From August 2002 to July 2003, we prospectively obtained invasive pneumococcal isolates from children <15 ...
Background: Measles remains a major public health problem in Mozambique despite significant efforts to control the disease. Currently, health authorities base their outbreak control on data from the routine surveillance system while vaccine coverage and efficacy are calculated based on mathematical proje...
Malaria occurs mostly in the tropical regions of the world. Sub-Saharan Africa is the area most affected. The occurrence of a very efficient mosquito vectors Anopheles gambiae complex and Anopheles funestus group sustain high transmission of the Plasmodium falciparum, the most predominant and deadly mala...
