Results: 106

Community-based progress indicators for prevention of mother-to-child transmission and mortality rates in HIV-exposed children in rural Mozambique

Background: Eliminating mother-to-child HIV-transmission (EMTCT) implies a case rate target of new pediatric HIV-infections< 50/100,000 live-births and a transmission rate < 5%. We assessed these indicators at community-level in Mozambique, where MTCT is the second highest globally.. Methods: A cross-sec...

Reduced Placental Transfer of Antibodies Against a Wide Range of Microbial and Vaccine Antigens in HIV-Infected Women in Mozambique

Front. immunol; 12 (), 2021
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...

Characteristics of adolescents aged 15-19 years living with vertically and horizontally acquired HIV in Nampula, Mozambique

PLoS One; 16 (4), 2021
Background: Adolescents living with HIV (ALHIV) 15-19 years of age are a growing proportion of all people living with HIV globally and the population includes adolescents with vertically acquired HIV (AVH) and behaviorally acquired HIV (ABH). Methods: We conducted a survey to measure sociodemographic ch...

High level of HIV false positives using EIA-based algorithm in survey: Importance of confirmatory testing

PLos ONE; 15 (10), 2020
Effective implementation of the national Human Immunodeficiency Virus (HIV) programs require monitoring the HIV epidemic trends to identify programmatic successes, challenges, and needed improvements. HIV prevalence estimates, defined as the percentage of a population affected by HIV, are calculated by t...

Covariates and spatial interpolation of hiv screening in mozambique: insight from the 2015 aids indicator survey

Examinamos os fatores associados ao rastreamento do vírus da imunodeficiência humana (HIV) e desenvolvemos um mapa de superfície de prevalência de rastreamento de HIV usando técnicas de interpolação espacial para identificar as áreas geográficas com as maiores e menores taxas de rastreamento de ...

Quality assurance for point-of-care testing in Mozambique’s National Health Service

Medical care in Mozambique is mostly provided through the national health service of the Ministry of Health. All primary healthcare and HIV-related services are provided free of charge. There are over 1500 public sector health facilities in Mozambique and most of these are primary healthcare centres. Alt...

Patterns of cardiovascular risk and disease in HIV-positive adults on anti-retroviral therapy in Mozambique

Introduction: With improved access to anti-retroviral therapy (ART) the focus of HIV treatment is changing to reducing chronic co-morbidities and their effects, but guidelines for HIV care in many African countries do not include screening for cardiac disease. Our study aimed to determine the pattern of ...

Factors associated with HIV serodiscordance among couples in Mozambique: Comparison of the 2009 INSIDA and 2015 IMASIDA surveys

PLos ONE; 15 (6), 2020
Recent studies suggest that a large proportion of new HIV-1 infections in mature epidemics occurs within discordant couples, making discordancy a major contributor to the spread of HIV/AIDS in Africa. This paper aims at assessing changes over a five-year period (2009-2015) on the (risk) factors associate...

Prevalence and risk factors associated with hiv/hepatitis b and HIV/hepatitis C co infections among people who inject drugs in mozambique

Background: There is scare information about HIV co-infections with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) among People Who Inject Drugs (PWID) in Mozambique. This information is critical to ensure the treatment necessary to decrease the progression of liver disease and the transmission o...

Using repeated home-based HIV testing services to reach and diagnose HIV infection among persons who have never tested for HIV, Chókwè health demographic surveillance system, Chókwè district, Mozambique, 2014-2017

PLos ONE; 15 (11), 2020
Background: HIV prevalence in Mozambique (12.6%) is one of the highest in the world, yet ~40% of people living with HIV (PLHIV) do not know their HIV status. Strategies to increase HIV testing uptake and diagnosis among PLHIV are urgently needed. Home-based HIV testing services (HBHTS) have been evaluate...