Results: 1669

COVID-19 school closures and mental health of adolescent students: Evidence from rural Mozambique
COVID-19 school closures and mental health of adolescent students: Evidence from rural Mozambique

SSM. Mental health; (), 2023
The onset of the COVID-19 pandemic, entailing widespread school closures as well as acute disruptions to household livelihoods, had substantial consequences for adolescent well-being in low-income countries. We present novel evidence about the prevalence of mental health challenges among adolescent stude...

SARS-CoV-2 seroprevalence and associated factors, based on HIV serostatus, in young people in Sofala province, Mozambique

BMC infect. dis; 23 (1), 2023
n In Sofala province (Mozambique), young people living with HIV (YPLHIV) are estimated at 7% among people aged 15–24 years. Even though the COVID-19 pandemic threatened HIV health services, data on the impact of COVID-19 on YPLHIV people are lacking. This study aimed at exploring the seroprevalence o...

Emergence of bedaquiline-resistant tuberculosis and of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis strains with rpoB Ile491Phe mutation not detected by Xpert MTB/RIF in Mozambique: a retrospective observational study

Lancet, Infect. dis.; 12 (23), 2023
Background In 2021, an estimated 4800 people developed rifampicin-resistant tuberculosis in Mozambique, 75% of which went undiagnosed. Detailed molecular data on rifampicin-resistant and multidrug-resistant (MDR) tuberculosis are not available. Here, we aimed at gaining precise data on the determinants o...

Diagnostic accuracy of a three-gene Mycobacterium tuberculosis host response cartridge using fingerstick blood for childhood tuberculosis: a multicentre prospective study in low-income and middle-income countries

Lancet, Infect. dis.; 12 (23), 2023
Background Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using easy-to-obtain specimens are needed. We aimed to assess the diagnostic accuracy of the Cepheid Mycobacterium tuberculosis Host Response pr...

Correlated depressive symptoms within seroconcordant, expectant partners living with HIV in Zambézia Province, Mozambique: a cross-sectional study

AIDS care; 35 (11), 2023
Approximately 15% of people with HIV in sub-Saharan Africa have comorbid depression, which impacts treatment outcomes. We describe predictors of baseline depressive symptoms in 1079 female and 1079 male participants in a cluster-randomized trial in Zambézia Province, Mozambique from November 2017 to Dec...

Retention in Care and Virological Failure among Adult HIV-Positive Patients on First-Line Antiretroviral Treatment in Maputo, Mozambique

Viruses; 15 (10), 2023
Access to antiretroviral treatment (ART) is increasingly available worldwide; however, the number of patients lost to follow-up and number of treatment failures continue to challenge most African countries. Objectives: To analyse the retention in clinical care and the virological response and their asso...

Changing patterns in the burden of paediatric injuries during the COVID-19 pandemic: a study in Mozambique’s central hospitals

Introdução: Há um corpo substancial de conhecimento sobre os efeitos da pandemia de COVID-19 nas lesões, mostrando reduções frequentes, mas inconsistentes, tanto no volume quanto no padrão. No entanto, estudos especificamente direcionados a crianças são menos comuns, principalmente em países de...

Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of P. falciparum uncomplicated malaria in African pregnant women (PYRAPREG): study protocol for a phase 3, non-inferiority, randomised open-label clinical trial

BMJ Open; 13 (10), 2023
Malaria infection during pregnancy increases the risk of low birth weight and infant mortality and should be prevented and treated. Artemisinin-based combination treatments are generally well tolerated, safe and effective; the most used being artemether-lumefantrine (AL) and dihydroartemisinin-piperaquin...

Favorable Impact of Community Adherence Support Groups on Retention in Care and Viral Suppression Rates Among Persons with HIV Receiving Antiretroviral Therapy in Mozambique

AIDS res. hum. retrovir; 39 (10), 2023
The community adherence support group (CASG) was one of the first differentiated service delivery (DSD) models introduced in Mozambique. This study assessed the impact of this model on retention in care, loss to follow-up (LTFU), and viral suppression among antiretroviral therapy (ART)-treated adults in ...

Segundo Plano de Aceleração da Resposta ao HIV e SIDA em Moçambique, 2024 – 2026
Second plan to accelerate the response to HIV and AIDS in Mozambique, 2024-2026

O Governo de Moçambique é signatário dos Objectivos para o Desenvolvimento Sustentável, que incluem o controlo do HIV, das metas dos 95-95-95 (pessoas vivendo com HIV que conhecem seu seroestado de HIV; pessoas vivendo com HIV que conhecem seu seroestado de HIV e estão em TARV; pessoas vivendo co...