Enfuvirtide was the first fusion inhibitor approved by the Food and Drug Administration (FDA) in 2003 for HIV-1 infection in treatment-experienced patient. It is the first approved antiviral agent to attack the HIV life cycle in its early stages. For HIV fusion to occur, the HR1 and HR2 domains in the gp...
HIV-1/genetics,
Amino Acid Sequence,
Anti-HIV Agents,
Cluster Analysis,
Drug Resistance, Viral,
Enfuvirtide,
Genotype,
HIV Envelope Protein gp41/genetics,
HIV Infections/virology,
HIV-1/classification,
Molecular Sequence Data,
Mozambique,
Mutation, Missense,
Peptide Fragments,
Phylogeny,
Polymorphism, Genetic,
RNA, Viral,
Sequence Alignment,
Sequence Analysis, DNA,
Treatment Failure
This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patients (ANRS 12146-CARINEMO) trial, which assessed the pharmacokinetics of rifampin or isoniazid with or without the coadm...
HIV/drug effects,
Antitubercular Agents/administration & dosage,
Benzoxazines,
Mycobacterium,
Mycobacterium tuberculosis/drug effects,
Tuberculosis/drug therapy,
Acquired Immunodeficiency Syndrome/epidemiology,
HIV Seroprevalence/trends,
Hepatitis/diagnosis,
CD4 Antigens/drug effects,
Mozambique/epidemiology
Feldblum, Paul J;
Enosse, Sónia;
Dubé, Karine;
Arnaldo, Paulo;
Muluana, Chadreque;
Banze, Reginaldo;
Nhanala, Aristides;
Cunaca, Joana;
Chen, Pai-Lien;
L Robb, Merlin;
Thompson, Ricardo.
Reliable HIV incidence estimates for Mozambique are limited. We conducted a prospective HIV incidence study as part of a clinical research site development initiative in Chókwè district, Gaza Province, southern Mozambique.
Methods: Between June 2010 and October 2012, we recruited women at sites where ...
objectiveCommunity ART groups (CAG), peer support groups involved in community ARTdistribution and mutual psychosocial support, were piloted to respond to staggering antiretroviraltreatment (ART) attrition in Mozambique. To understand the impact of CAG on long-term retention,we estimated mortality and lo...
Mozambique,
Mortality,
Acquired Immunodeficiency Syndrome,
Psychosocial Support Systems,
Persons,
Cohort Studies,
HIV,
Residence Characteristics,
Health Services Accessibility,
Patients,
Prevalence,
World Health Organization,
Community Participation,
Medicine,
Risk Factors,
CD4 Lymphocyte Count
A primary concern for the RTS,S malaria vaccine candidate is duration of protection. The ongoing Phase III trial reported evidence of waning efficacy within the first year following vaccination. Multiple Phase IIb trials demonstrated early waning of efficacy. The longest duration of protection for RTS,S ...
Immunoglobulin G/blood,
Antibodies, Protozoan/blood,
Malaria Vaccines/immunology,
Malaria Vaccines/therapeutic use,
Mozambique,
Malaria, Falciparum/prevention & control,
Parasitemia/prevention & control,
Randomized Controlled Trials as Topic,
Plasmodium falciparum
O Programa Nacional de Controlo (PNC) de ITS-HIV/SIDA é a entidade responsável do Sistema Nacional de Saúde para a gestão dos serviços de saúde relacionados ao HIV. A sua missão é de coordenação, regulamentação e prestação de cuidados e tratamento aos pacientes vivendo com HIV. Para respond...
Annual Report,
HIV,
Acquired Immunodeficiency Syndrome,
Activities of Daily Living,
Anti-Retroviral Agents,
Therapeutics,
Disease Transmission, Infectious,
Communicable Disease Control,
Circumcision, Male,
Mozambique,
Sexually Transmitted Diseases,
Health Policy,
Health Services Administration,
National Health Systems
Os autores reportam um caso de Leucemia Linfoblástica Aguda - L1 da classificação Francesa – Americana – Britânica, numa criança moçambicana cujo diagnóstico específico foi confirmado através de consulta por via electrónica,realizada por um hospital rural em Moçambique e por um oncologista...
Lymphadenopathy,
Leukemia, Biphenotypic, Acute/blood,
d0007400,
d0067800,
d0541980,
d0172160,
d0062950,
Radiation Oncologists,
Mozambique
V, Noormahomed E;
N, Nhancupe;
M, Zalis;
Y, assane;
T, buene;
L, banze;
SMS, afonso;
C, cuthrie;
T, schooley r;
P, cappuccinelli;
M, colombo.
Introdução e objectivos: A cisticercose e neurocisticercose (NCC) causadas pela larva de T. solium, o Cysticercus cellulosae é uma enfermidade negligenciada responsável por epilepsia de início tardio e convulsões em crianças sem febre nos países endémicos. A falta de inquéritos epidemiológicos...
As duas últimas décadas registaram um de senvolvimento sem precedentes da investigação científica em saúde em Moçambique. Em parte,este desenvolvimento foi catalisado pelo amadure cimento de um sistema de ciência e tecnologia no País que providencia uma matriz de suporte para a realização de i...
A arte e saúde caminham juntos desde a pre história quando o homem primitivo tinha que tomar várias iniciativas para a sua sobrevivência. Os desenhos encotrados em várias grutas atestam a crença segundo a qual, antes de partir para a caça, este acto, era primeiro materializado artisticamente nasro...
