Introduction: With improved access to anti-retroviral therapy (ART) the focus of HIV treatment is changing to reducing chronic co-morbidities and their effects, but guidelines for HIV care in many African countries do not include screening for cardiac disease. Our study aimed to determine the pattern of ...
Recent studies suggest that a large proportion of new HIV-1 infections in mature epidemics occurs within discordant couples, making discordancy a major contributor to the spread of HIV/AIDS in Africa. This paper aims at assessing changes over a five-year period (2009-2015) on the (risk) factors associate...
Background: There is scare information about HIV co-infections with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) among People Who Inject Drugs (PWID) in Mozambique. This information is critical to ensure the treatment necessary to decrease the progression of liver disease and the transmission o...
Hepatitis B/epidemiology,
HIV,
Substance-Related Disorders,
Viral Load,
Ambulatory Care,
Hepatitis C,
Infections,
Prevalence,
Risk Factors,
Drug Users,
Coinfection/epidemiology,
Coinfection/psychology,
Coinfection/virology,
Drug Users/psychology,
Drug Users/statistics & numerical data,
Epidemics,
HIV Infections/epidemiology,
HIV Infections/psychology,
HIV Infections/virology,
Hepacivirus,
Hepatitis B/psychology,
Hepatitis B/virology,
Hepatitis B virus,
Hepatitis C/epidemiology
Background: HIV prevalence in Mozambique (12.6%) is one of the highest in the world, yet ~40% of people living with HIV (PLHIV) do not know their HIV status. Strategies to increase HIV testing uptake and diagnosis among PLHIV are urgently needed. Home-based HIV testing services (HBHTS) have been evaluate...
Soro, Laura Fuente;
Varela, Elisa López;
Augusto, Orvalho;
Bernardo, Edson Luis;
Sacoor, Charfudin;
Nhacolo, Ariel;
Castillo, Paula Ruiz;
Alfredo, Charity;
Karajeanes, Esmeralda;
Vaz, Paula;
Naniche, Denise.
Patients lost to follow-up (LTFU) over the human immunodeficiency virus (HIV) cascade have poor clinical outcomes and contribute to onward HIV transmission. We assessed true care outcomes and factors associated with successful reengagement in patients LTFU in southern Mozambique.
Newly diagnosed HIV-posi...
Background: Determination of the human immunodeficiency virus (HIV) exposure status in infants and young children is required to guarantee timely diagnosis and access to appropriate care. HIV prevalence among Mozambican women aged 15-49 years is 15%, and vertical transmission rate is still high. The stud...
Breast Feeding,
HIV Infections/epidemiology,
HIV Infections/prevention & control,
HIV Infections/transmission,
Infectious Disease Transmission, Vertical/prevention & control,
Infectious Disease Transmission, Vertical/statistics & numerical data,
Malaria/epidemiology,
Malaria/prevention & control,
Risk Factors,
Vaccination Coverage/statistics & numerical data,
Mothers/statistics & numerical data,
Socioeconomic Factors,
Mozambique/epidemiology,
Prevalence
Mozambique has one of the highest burdens of HIV globally, and people who inject drugs (PWID) have one of thehighest HIV infection rates in Africa. After the implementation of the first Biological Behavioral Surveillance (BBS)
Survey among PWID in Mozambique, the Ministry of Health started the developmen...
Pharmaceutical Preparations,
HIV Infections/complications,
Epidemics,
Vulnerable Populations,
Biological Products,
Harm Reduction,
Adolescent,
Drug Users,
Mozambique,
HIV Infections/prevention & control,
Needle-Exchange Programs/methods,
Substance Abuse, Intravenous/complications
Vaz, paula;
Buck, w, chris;
Bhatt, Nilesh;
Bila, Dulce;
Auld, andrew;
Houston, James;
Cossa, loide;
Alfredo, Charity;
Jobarteh, kebba;
Sabatier, jennifer.
Background: Virologic failure (VF) is highly prevalent in sub-Saharan African children on antiretroviral therapy (ART) and is often associated with human immunodeficiency virus drug resistance (DR). Most children still lack access to routine viral load (VL) monitoring for early identification of treatmen...
Anti-Retroviral Agents/therapeutic use,
Drug Resistance, Viral,
HIV/radiation effects,
HIV Infections/therapy,
HIV Infections/virology,
Lamivudine/therapeutic use,
Lamivudine/pharmacology,
Nevirapine/pharmacology,
Nevirapine/therapeutic use,
Stavudine/pharmacology,
Stavudine/therapeutic use,
Viral Load
Introduction: Viral load testing is essential to manage HIV disease, especially in infants and children. Early infant diagnosis (EID) is performed using nucleic-acid testing in children under 18 months. Resource-limited health systems face severe challenges to scale-up both viral load and EID to unpreced...
HIV Infections/diagnosis,
HIV Infections/virology,
HIV-1/genetics,
HIV-1/isolation & purification,
HIV-1/physiology,
Infant, Newborn, Diseases/diagnosis,
Infant, Newborn, Diseases/virology,
Mozambique,
Sensitivity and Specificity,
Prospective Studies,
Viral Load/methods,
Viremia/diagnosis,
Viremia/virology
Abstract: Mozambique has a high burden of HIV and is currently ranked sixth worldwide for adult prevalence. In Mozambique, HIV prevalence is not uniformly distributed geographically and throughout the population. We investigated the spatial distribution of HIV infection among adolescents and young people...
