Results: 40

MARVEL-minimising the emergence and dissemination of HIV-1 drug resistance in Portuguese-speaking African Countries (PALOP): low-cost portable NGS platform for HIV-1 surveillance in Africa

BMC infect. dis; 24 (1), 2024
Background HIV-1 infections remain a global public health concern. Scaled-up antiretroviral treatment (ART) is crucial for reducing morbidity and mortality related to HIV/AIDS. The emergence of drug-resistance mutations (DRMs) compromises viral suppression and contributes to the continued HIV-1 transmiss...

Alternative approaches for creating a wealth index: the case of Mozambique

BMJ glob. health; 8 (8), 2023
Background Residual malaria transmission is the result of adaptive mosquito behavior that allows malaria vectors to thrive and sustain transmission in the presence of good access to bed nets or insecticide residual spraying. These behaviors include crepuscular and outdoor feeding as well as intermittent ...

Verbal and social autopsy of adult deaths and adult care-seeking pattern in mozambique, 2019-2020

Am. j. trop. med. hyg; 108 (5), 2023
In sub-Saharan Africa, recent data about causes of adult death and care-seeking during illnesses are limited. This analysis examines adult deaths using verbal and social autopsy data from a nationally and provincially representative sample registration system in Mozambique. Causes of death among those 18...

Benefits and challenges of consolidating public health functions into a National Public Health Institute: a policy analysis

Health policy plan; 38 (3), 2023
National Public Health Institutes (NPHIs) around the world vary in composition. Consolidated organizational models can bring together critical functions such as disease surveillance, emergency preparedness and response, public health research, workforce development and laboratory diagnosis within a singl...

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

Science .; 378 (), 2022
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoun...

Impact of the Implementation of Laboratory Information System (WWDISA) on Timely Provision of HIV-1 Viral Load Results in a Rural Area, Inhambane, Mozambique

WWDISA is an optional module of the DISA Laboratory Information system (LIS) that offers a web portal that allows access to test results over the internet for patient clinical management. This study aims to assess the applicability of using the WWDISA web application, and the lessons learned from its imp...

COVID-19 imported cases and severity: expected information from genomic characterization of SARS-CoV-2 strains in Mozambique

J. infect. dev. ctries; 15 (12), 2021
Introduction: The novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), etiological agent of coronavirus disease 2019 (COVID-19) was first reported in China in December 2019 and spread worldwide. As of March 6th, 2021, there have been 116,670,105 million confirmed cases globall...

Os Dilemas Bioéticos do Impacto da COVID-19 nos Sistemas de Saúde Africanos
The Bioethical Dilemmas of the Impact of COVID-19 on Systems African Health More about

A partir de uma revisão bibliográfica sobre os efeitos da pandemia da COVID-19, o artigo apresenta e analisa os dilemas bioéticos que surgem da necessidade de dedicar mais recursos sanitários ao controlo da mesma. Os esforços por controlar a propagação do SARS-CoV-2 significaram diminuição da at...

Infant vaccination against malaria in Mozambique and in Togo: mapping parents' willingness to get their children vaccinated

Background: Malaria is one of the most widespread and deadly diseases worldwide and large majority of malaria cases and deaths occurs in Africa. Efforts to develop an effective vaccine against malaria are underway and several vaccine prototypes are on different clinical trial phases.Objective: As many su...

Improving birth and death data for African decision making

Lancet Glob. Health; 8 (1), 2020
The scarcity of current, complete, and accurate primary data on causes of death in most of sub-Saharan Africa restricts the ability of countries to measure progress against many of the Sustainable Development Goal targets, measure the impact of programmatic interventions, prioritise and ...