Undernutrition, anemia, and intestinal parasitic infections are public health problems in Angola, especially in pre-school children. We analyzed binary data from a longitudinal four-arm randomizedparallel trial conducted in Bengo Province, northern Angola, over the course of two years, with seven follow-...
Wasting Syndrome/parasitology,
Anemia/diagnosis,
Child Nutrition Disorders/drug therapy,
Angola/epidemiology,
Growth Disorders/therapy,
Anemia/etiology,
Albendazole/therapeutic use,
Inflammatory Bowel Diseases/parasitology,
Parasitic Diseases/diagnosis,
Parasites,
Diarrhea/drug therapy
Globalmente, a crise sócio-económica desencadeada pela pandemia da CVID-19 constitui um risco gravi ao estado nutricional e de sobrevivência de criaças de países de baixa e média renda. 1No contexto actual da pandemia espera-se que haja um aumento na desnutrição infantil devido a factores diverco...
Infant Mortality/trends,
Child Nutrition Disorders/prevention & control,
Breast Feeding,
COVID-19,
Health Services Accessibility,
Anemia/diagnosis,
Maternal Mortality/trends,
Mozambique,
Postnatal Care,
Vaccines/immunology,
Infant, Premature,
Asphyxia Neonatorum,
Neonatal Sepsis,
Pneumonia,
Malaria,
Postpartum Hemorrhage
Introdução: Moçambique é um dos países endémicos à malária. Em 2011, a estimativa de prevalência desta doença era de 40–80% em crianças dos 2–9 anos e 90% em crianças menores de 5 anos. Estas altas prevalências podem ser devido à dificuldade das crianças em desenvolverem uma resposta i...
Moraleda, Cinta;
Aguilar, Ruth;
Quinto, Llorenç;
Nhampossa, Tacilta;
Renom, Montserrat;
Nhabomba, Augusto;
Acacio, Sozinho;
Aponte, John J;
Nhalingo, Delino;
Achtman, Ariel H;
Scholfield, Louis 6 7 8;
Martins, Helder 4;
Macete, Eusebio;
Alonso, Pedro L;
Menendez, Clara.
Young children bear the world's highest prevalence of anaemia, the majority of which is of multifactorial aetiology, which in turn hampers its successful prevention. Even moderate degrees of anaemia are associated with increased mortality and morbidity. Despite this evidence, there is a lack of effective...
Hemminki, Elina;
Nwaru, Bright I;
Salomé, Graca;
Parkkali, Saara;
Abacassamo, Fatima;
Augusto, Orvalho;
Cliff, Julie;
Regushevskaya, Elena;
Dgedge, Martinho;
Sousa, Cesar;
Chilundo, Baltazar.
To compare routine versus selective (ie, screening and treatment for anaemia) prenatal iron prophylaxis in a malaria-endemic and HIV-prevalent setting, an extended analysis including previously missing data.
Design: A pragmatic randomised controlled clinical trial.
Setting: 2 health centres in Maputo, ...
Anemia/prevention & control,
Cesarean Section/statistics & numerical data,
Dietary Supplements,
Ferrous Compounds/administration & dosage,
Folic Acid/administration & dosage,
HIV Infections/complications,
Hemoglobins/analysis,
Iron/administration & dosage,
Malaria/complications,
Maternal Death/statistics & numerical data,
Mozambique,
Perinatal Death,
Premature Birth/epidemiology,
Prenatal Care/methods
Schacht, Caroline De;
Lucas, Carlota;
Sitoe, Nádia;
Machekano, Rhoderick;
Chongo, Patrina;
Temmerman, Marleen;
Tobaiwa, Ocean;
Guay, Laura;
Kassaye, Seble;
Jani, Ilesh V.
Introduction: Anemia, syphilis and HIV are high burden diseases among pregnant women in sub-Saharan Africa. A quasi-experimental study was conducted in four health facilities in Southern Mozambique to evaluate the effect of point-of-care technologies for hemoglobin quantification, syphilis testing and CD...
Anemia/diagnosis,
Anti-Retroviral Agents,
CD4 Lymphocyte Count,
CD4-Positive T-Lymphocytes,
HIV Infections,
Maternal-Child Health Centers,
Pregnancy Complications, Infectious,
Prenatal Diagnosis,
Rural Health Services,
Retrospective Studies,
Syphilis/diagnosis,
Syphilis Serodiagnosis,
Mozambique
Aguilar 1, Ruth;
Moraleda, Cinta;
Achtman, Ariel H;
Mayor, Alfredo;
Quintó, Llorenç;
Cisteró, Pau;
Nhabomba, Augusto;
Macete, Eusebio;
Schofield, Louis;
Alonso, Pedro L;
Menéndez, Clara.
There are no large-scale ex vivo studies addressing the contribution of Plasmodium falciparum in the bone marrow to anaemia. The presence of malaria parasites and haemozoin were studied in bone marrows from 290 anaemic children attending a rural hospital in Mozambique. eripheral blood infections were det...
Anemia/blood,
Anemia/parasitology,
Bone Marrow/parasitology,
Case-Control Studies,
Hemeproteins/metabolism,
Malaria, Falciparum/blood,
Malaria, Falciparum/pathology,
Plasmodium falciparum/growth & development,
Mozambique
Aguilar, Ruth;
Tejada, Ariel Magallon;
Achtman, Ariel H;
Moraleda, Cinta;
Joice, Regina;
Cisteró, Pau;
Suen, Connie S. N. Li Wai;
Nhabomba, Augusto;
Macete, Eusebio;
Mueller, Ivo;
Marti, Matthias;
Alonso, Pedro L;
Menéndez, Clara;
Schofield, Louis;
Mayor, Alfredo.
Plasmodium falciparum immature gametocytes are not observed in peripheral blood. However, gametocyte stages in organs such as bone marrow have never been assessed by molecular techniques, which are more sensitive than optical microscopy. We quantified P falciparum sexual stages in bone marrow (n = 174) a...
Anemia/parasitology,
Anemia/genetics,
Bone Marrow/pathology,
Bone Marrow/parasitology,
DNA, Protozoan/analysis,
Life Cycle Stages/genetics,
Malaria, Falciparum/diagnosis,
Malaria, Falciparum/genetics,
Malaria, Falciparum/parasitology,
Molecular Diagnostic Techniques,
Plasmodium falciparum/genetics,
Plasmodium falciparum/growth & development,
Plasmodium falciparum/isolation & purification,
Polymerase Chain Reaction,
Mozambique
This study aims to assess the association between schistosomiasis and hookworm infection with hemoglobin levels of schoolchildren in northern Mozambique. Through a cross-sectional survey, 1,015 children from five to 12 years old in the provinces of Nampula, Cabo Delgado and Niassa were studied. Hookworm ...
Human immunodeficiency virus (HIV)-1 infection has an important impact on malaria. Plasmodium falciparum
and HIV-1 co-infected patients (Pf/HIV) present with a high degree of anaemia, enhanced parasitaemia and decreased
CD4+ T cell counts, which increase the risk of developing severe malaria. In addition...
