Methods: We conducted antibiotic susceptibility testing on 157 stool isolates recovered from 129 patients aged between 0 and 80 years with diarrhea, including HIV infected (n = 68) and-uninfected individuals (n = 61), assisted at two health centers in Maputo city. The isolates comprised of 99 Salmonella,...
Agar,
Anti-Bacterial Agents/pharmacology,
Anti-Bacterial Agents/therapeutic use,
Azithromycin,
Bacteria,
Campylobacter,
Diarrhea/microbiology,
Diarrhea/epidemiology,
Drug Resistance, Bacterial,
Drug Resistance, Multiple,
Erythromycin,
Gentamicins/pharmacology,
Gentamicins/therapeutic use,
HIV Infections/complications,
HIV Infections/epidemiology,
Microbial Sensitivity Tests,
Mozambique/epidemiology,
Salmonella,
Sheep,
Shigella,
Tetracycline
Coutinho, lena manhique;
Paula, chiani;
Michelacci, valeria;
Taviani, elisa;
Bauhofer, adilson fernando;
Chissaque, Assecênio;
Moiane, idalécia cossa;
Sambo, Júlia;
Chilaúle, jorfélia;
Guimarães, esperança lourenço;
Salência, Judite;
Cassocera, Marta;
Bero, Diocreciano Matias;
Langa, José paulo;
Deus, nilsa.
Objectives: Analyze the frequency of diarrheagenic Escherichia coli (DEC) pathotypes and their antimicrobial resistance profiles among children aged <15 years with diarrhea in four Mozambican provinces.
Methods: A cross-sectional hospital-based surveillance program of diarrhea was implemented in Maputo,...
Coutinho, Lena Manhique;
Chiani, Paola;
Michelacci, Valeria;
Taviani, Elisa;
Bauhofer, Adilson Fernando Loforte;
Chissaque, Assucênio;
Cossa-Moiane, Idalécia;
Sambo, Júlia;
Chilaúle, Jorfélia;
Guimarães, Esperança Lourenço;
Salência, Judite;
Cassocera, Marta;
Bero, Diocreciano Matias;
Langa, José Paulo;
De Deus, Nilsa.
Analyze the frequency of diarrheagenic Escherichia coli (DEC) pathotypes and their antimicrobial resistance profiles among children aged <15 years with diarrhea in four Mozambican provinces.
Methods: A cross-sectional hospital-based surveillance program of diarrhea was implemented in Maputo,
Sofala, Zamb...
Background: S. pneumoniae is the leading cause of acute bacterial meningitis (ABM) in children. Vaccination using the 10-valent conjugate vaccine (PCV-10) was recently introduced into the National Immunization Program in Mozambique, but data on serotype coverage of this vaccine formulation are scarce. In...
Anti-Bacterial Agents/pharmacology,
Pneumococcal Vaccines,
DNA, Bacterial/analysis,
Ceftriaxone/pharmacology,
Microbial Sensitivity Tests,
Drug Resistance, Multiple, Bacterial,
Epidemiological Monitoring,
Meningitis, Bacterial/epidemiology,
Meningitis, Bacterial/microbiology,
Meningitis, Bacterial/prevention & control,
Penicillins/pharmacology,
Pneumococcal Infections/immunology,
Pneumococcal Infections/microbiology,
Pneumococcal Vaccines/administration & dosage,
Streptococcus pneumoniae/classification,
Streptococcus pneumoniae/genetics,
Streptococcus pneumoniae/isolation & purification,
Streptococcus pneumoniae/radiation effects,
Polymerase Chain Reaction,
Mozambique/epidemiology
The antioxidant capacity and antimicrobial activity of the essential oil of Moringa oleifera (Moringaceae) grown in Mozambique was investigated. The chemical composition was studied by means of GC and GC-MS analysis. Hexacosane (13.9%), pentacosane (13.3%) and heptacosane (11.4%) were the main components...
Anti-Bacterial Agents/isolation & purification,
Anti-Bacterial Agents/chemistry,
Anti-Bacterial Agents/pharmacology,
Mozambique,
Antifungal Agents/isolation & purification,
Antifungal Agents/pharmacology,
Moringa oleifera/chemistry,
Oils, Volatile/chemistry,
Oils, Volatile/isolation & purification,
Oils, Volatile/pharmacology,
Plant Leaves/chemistry,
Plant Oils/isolation & purification,
Plant Oils/pharmacology,
Quercetin
Mandomando, Inácio;
Sigaúque, Betuel;
Morais, Luís;
Espasa, Mateus;
Valles, Xavier;
Sacarlal, Jahit;
Macete, Eusébio;
Assessor, Pedro;
Quinto, Llorenç;
Nhampossa, Tacilta;
Machevo, Sónia;
Bassat, Quique;
Menendez, Clara;
Ruiz, Joaquim;
Roca, Ana;
Alonso, Pedro L.
Abstract. Antibiotic resistance in Africa is increasing but insufficiently recognized as a public health problem. However, there are scarce data for antimicrobial resistance trends among bloodstream isolates in sub-Saharan Africa. Antimicrobial drug resistance trends among bacteria isolated from blood of...
Anti-Bacterial Agents/pharmacology,
Ampicillin/pharmacology,
Africa South of the Sahara,
Africa,
Bacteremia/physiopathology,
Chloramphenicol/pharmacology,
Drug Resistance, Microbial/physiology,
Enterobacteriaceae Infections/physiopathology,
Escherichia coli/drug effects,
Haemophilus Infections,
Haemophilus influenzae/radiation effects,
Hospitals, Rural/statistics & numerical data,
Microbial Sensitivity Tests/trends,
Salmonella typhi/drug effects,
Staphylococcus aureus/drug effects,
Mozambique/epidemiology
Mandomand, inacio;
Espasa, mateu;
Valles, xavier;
Pons, maria J;
Jaintilal, dinis;
Mensa, laura;
Macete, eusebio;
Sacarlal, jahit;
Sanz, Sergi;
Sigauque, Betuel;
Abacassamo, fatima;
Alonso, pedro L;
Ruiz, joaquim.
The antimicrobial susceptibility and mechanisms of resistance of 109 Shigella and 40 Salmonella isolates from children with diarrhea in southern Mozambique were assessed. The susceptibility to seven antimicrobial agents was tested by disk diffusion, and mechanisms of resistance were searched by PCR or co...
Sigaúque, betuel;
Mandomando, inácio;
Roca, anna;
Morais, luís;
Quintó, llorenç;
Sacarlal, jahit;
Nhamposa, tacilta;
Macete, eusébio;
Machevo, sónia;
Aide, pedro;
Bardají, azucena;
Bassat, quique;
Nhalungo, delino;
Soriano-Gabarró, montse;
Flannery, brendan;
Menendez, clara;
Alonso, pedro L;
Levine, myron M.
Background: Although community-acquired bacteremia is an important cause of childhood mortality in Africa, recognition of disease burden and potential impact of bacterial vaccines is limited. ethods: Blood cultures for bacterial pathogens were conducted systematically among children <15 years of age admi...
Sigaúque, B;
Roca, A;
Sanz, S;
Oliveiras, I;
Martínez, M;
Mandomando, inacio;
Vallès, X;
Espasa, mateu;
Abacassamo, F;
Sacarlal, J;
Macete, eusebio;
Nhacolo, A;
Aponte, J;
Levine, M. M;
Alonso, P. L.
Introduction: Acute bacterial meningitis (ABM) is one of the most severe diseases in Sub-Saharan Africa. Although data for the continent is very limited, more than one million cases are estimated per year, with mortality and life-long sequelae occurring in 50% of these cases. Methods: As part of the clin...
Anti-Bacterial Agents/pharmacology,
Gram-Negative Bacteria/isolation & purification,
Gram-Negative Bacterial Infections/epidemiology,
Gram-Negative Bacterial Infections/microbiology,
Gram-Negative Bacterial Infections/mortality,
Gram-Positive Bacterial Infections/epidemiology,
Gram-Positive Bacterial Infections/microbiology,
Gram-Positive Bacterial Infections/mortality,
Meningitis, Bacterial/mortality,
Meningitis, Bacterial/epidemiology,
Meningitis, Bacterial/microbiology
Since the seventh pandemic caused by Vibrio cholerae biotype El Tor began in Indonesia in 1961, most regions of the world continue to report cholera outbreaks.1 Cholera is most common in rural areas or communities where sanitation conditions and water supply are problematic.2 In 1997, a cholera epidemic ...
Anti-Bacterial Agents/pharmacology,
Cholera/microbiology,
Data Interpretation, Statistical,
Drug Resistance, Bacterial,
Microbial Sensitivity Tests,
Rectum/microbiology,
Rural Population,
Vibrio cholerae O1/chemistry,
Cholera/drug therapy,
Cholera/prevention & control,
Mozambique
