Methods: We conducted antibiotic susceptibility testing on 157 stool isolates recovered from 129 patients aged between 0 and 80 years with diarrhea, including HIV infected (n = 68) and-uninfected individuals (n = 61), assisted at two health centers in Maputo city. The isolates comprised of 99 Salmonella,...
Agar,
Anti-Bacterial Agents/pharmacology,
Anti-Bacterial Agents/therapeutic use,
Azithromycin,
Bacteria,
Campylobacter,
Diarrhea/microbiology,
Diarrhea/epidemiology,
Drug Resistance, Bacterial,
Drug Resistance, Multiple,
Erythromycin,
Gentamicins/pharmacology,
Gentamicins/therapeutic use,
HIV Infections/complications,
HIV Infections/epidemiology,
Microbial Sensitivity Tests,
Mozambique/epidemiology,
Salmonella,
Sheep,
Shigella,
Tetracycline
Coutinho, lena manhique;
Paula, chiani;
Michelacci, valeria;
Taviani, elisa;
Bauhofer, adilson fernando;
Chissaque, Assecênio;
Moiane, idalécia cossa;
Sambo, Júlia;
Chilaúle, jorfélia;
Guimarães, esperança lourenço;
Salência, Judite;
Cassocera, Marta;
Bero, Diocreciano Matias;
Langa, José paulo;
Deus, nilsa.
Objectives: Analyze the frequency of diarrheagenic Escherichia coli (DEC) pathotypes and their antimicrobial resistance profiles among children aged <15 years with diarrhea in four Mozambican provinces.
Methods: A cross-sectional hospital-based surveillance program of diarrhea was implemented in Maputo,...
Antibiotic overuse is a major public health challenge worldwide and it can result in the emergence and spread of drug resistance. In Mozambique, there are limited data related to primary care physicians' antibiotic prescription patterns. The aim of this study was to assess the antibiotic prescription pat...
Coutinho, Lena Manhique;
Chiani, Paola;
Michelacci, Valeria;
Taviani, Elisa;
Bauhofer, Adilson Fernando Loforte;
Chissaque, Assucênio;
Cossa-Moiane, Idalécia;
Sambo, Júlia;
Chilaúle, Jorfélia;
Guimarães, Esperança Lourenço;
Salência, Judite;
Cassocera, Marta;
Bero, Diocreciano Matias;
Langa, José Paulo;
De Deus, Nilsa.
Analyze the frequency of diarrheagenic Escherichia coli (DEC) pathotypes and their antimicrobial resistance profiles among children aged <15 years with diarrhea in four Mozambican provinces.
Methods: A cross-sectional hospital-based surveillance program of diarrhea was implemented in Maputo,
Sofala, Zamb...
Kenga, Darlenne B;
Gebretsadik, Tebeb;
Simbine, Samuel;
Simbine, Samuel;
Maússe, Fabião E;
Charles, Pedro;
Zaqueu, Ernesto;
Fernando, Hermenegilda F;
Sacarlal, Jahit;
Moon, Troy D.
Background: Bacteremia is a major cause of morbidity and mortality worldwide. Children infected with HIV present with patterns of bacteremia generally associated with poor prognosis. In Mozambique, data on bacteremia are sparce.
Methods: We conducted an observational study of HIV-infected and HIV-expose...
Anti-Bacterial Agents/therapeutic use,
Bacteremia/epidemiology,
Bacteremia/drug therapy,
Community-Acquired Infections/drug therapy,
Community-Acquired Infections/epidemiology,
Fever/drug therapy,
HIV Infections/epidemiology,
HIV Infections/complications,
HIV Infections/drug therapy,
Microbial Sensitivity Tests,
Staphylococcal Infections/drug therapy,
Mozambique/epidemiology
Cambaco, olga;
Menendez, yara alonso;
Kinsman, john;
Sigaúque, betuel;
Wertheim, heiman;
Do, nga;
Gyapong, margaret;
John-Langba, johannes;
Sevene, esperança;
Munguambe, khátia.
Background: Antibiotic misuse and other types of unnecessary use of antibiotics can contribute to accelerate the process of antibiotic resistance, which is considered a global concern, mostly affecting low-and middle-income countries (LMICs). In Mozambique there is limited evidence on community knowledge...
Amoxicillin/therapeutic use,
Anti-Bacterial Agents/therapeutic use,
Awareness,
Drug Resistance, Microbial,
Focus Groups,
Health Knowledge, Attitudes, Practice,
Medication Adherence,
Mozambique,
Qualitative Research,
Rural Population,
Self Medication,
Drug Resistance, Bacterial,
Treatment Failure,
Health Strategies
Background Irrational use of antibiotics is a major driver of antimicrobial resistance (AMR) worldwide. Sub-Saharan Africa, where the risk of spread of AMR is highest, lacks data on the knowledge, attitudes and practices regarding antibiotic prescription and use. This is the first study in Mozambique toa...
Rationale: Mozambique has recorded cyclically epidemic outbreaks of cholera. Antibiotic therapy is recommended in specific situations for management and control of cholera outbreaks. However, an increase in resistance rates to antibiotics by Vibrio cholerae has been reported in several epidemic outbreaks...
Vibrio cholerae/drug effects,
Environmental Monitoring,
Drug Resistance, Microbial,
Health,
Tetracycline,
Vibrio cholerae/isolation & purification,
Mozambique/epidemiology,
Cholera/microbiology,
Cholera/epidemiology,
Anti-Bacterial Agents/therapeutic use
Introdução: A prescrição de antibióticos representa um problema global de saúde pública, e merece uma atenção especial, principalmente quando são prescritos a pacientes HIV seropositivos que dependem inteiramente de medicamentos para obter uma vida prolongada e com qualidade.
Objectivo: Preten...
