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Field performance of ultrasensitive and conventional malaria rapid diagnostic tests in southern Mozambique

Galatas, Beatriz; Mayor, Alfredo; Gupta, Himanshu; Balanza, Núria; Jang, Ihn Kyung; Nhamussua, Lidia; Simone, Wilson; Cistero, Pau; Chidimatembue, Arlindo; Munguambe, Humberto; Saute, Francisco; Aide, Pedro; Bassat, Quique.
Malar. j. (Online); 19 (1), 2020
An ultrasensitive malaria rapid diagnostic test (RDT) was recently developed for the improved detection of low-density Plasmodium falciparum infections. This study aimed to compare the diagnostic performance of the PfHRP2-based Abbott Malaria Ag P. falciparum ultrasensitive RDT (uRDT) to that of the conv...
Antigens, Protozoan/genetics, Parasitology/methods, d0077700, d0126800, Mozambique, Antigens, Protozoan/blood, Cross-Sectional Studies, Dried Blood Spot Testing/methods, Dried Blood Spot Testing/statistics & numerical data, Malaria, Falciparum/diagnosis, Parasitology/statistics & numerical data, Plasmodium falciparum/genetics
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Estimation of malaria-attributable fever in malaria test–positive febrile outpatients in three provinces of mozambique, 2018

Mateus, Plucinski; Baltazar, Candrinho; Marcia, Dimane; Tom, Smit; Julie, Thwing; James, Carbon; Rogier, Eric; Zullier, Rose.
Am. j. trop. med. hyg; 102 (1), 2020
Like most malaria-endemic countries, Mozambique relies on tabulation of confirmed malaria test–positive febrile patients to track incidence of malaria. However, this approach is potentially biased by incidental malaria parasitemia in patients with fever of another etiology. We compared pan-Plasmodium a...
Malaria/diagnosis, Malaria/ethnology, Fever/ethnology, Malaria/epidemiology, Antigens, Protozoan/blood, Mozambique/epidemiology, Malaria/pathology, Outpatients
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Assessing Performance of HRP2 Antigen Detection for Malaria Diagnosis in Mozambique

Plucinski, Mateusz M; Candrinho, Baltazar; Dimene, Mercia; Colborn, James; Lu, Austin; Nace, Doug; Zulliger, Rose; Rogier, Eric.
J. clin. microbiol; 57 (9), 2019
Rapid diagnostic tests (RDTs) that detect the Plasmodium falciparum-specific histidine-rich protein 2 (PfHRP2) antigen are the primary methods for malaria diagnosis in Mozambique. However, these tests do not detect infections with non-falciparum malaria or Pfhrp2- and Pfhrp3-deleted P. falciparum parasit...
Antigens, Protozoan/blood, Fructose-Bisphosphate Aldolase/blood, Immunoassay/methods, L-Lactate Dehydrogenase/blood, Plasmodium falciparum/genetics, Plasmodium falciparum/isolation & purification, Malaria, Falciparum/immunology, Malaria/diagnosis
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