RDSM – Rede de Documentação sobre Saúde em Moçambique

Field performance of ultrasensitive and conventional malaria rapid diagnostic tests in southern Mozambique

Galatas, Beatriz; Mayor, Alfredo; Gupta, Himanshu; Balanza, Núria; Jang, Ihn Kyung; Nhamussua, Lidia; Simone, Wilson; Cistero, Pau; Chidimatembue, Arlindo; Munguambe, Humberto; Saute, Francisco; Aide, Pedro; Bassat, Quique.

Malar. j. (Online); 19 (1), 2020

An ultrasensitive malaria rapid diagnostic test (RDT) was recently developed for the improved detection of low-density Plasmodium falciparum infections. This study aimed to compare the diagnostic performance of the PfHRP2-based Abbott Malaria Ag P. falciparum ultrasensitive RDT (uRDT) to that of the conv...

Antigens, Protozoan/genetics, Parasitology/methods, d0077700, d0126800, Mozambique, Antigens, Protozoan/blood, Cross-Sectional Studies, Dried Blood Spot Testing/methods, Dried Blood Spot Testing/statistics & numerical data, Malaria, Falciparum/diagnosis, Parasitology/statistics & numerical data, Plasmodium falciparum/genetics

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Multiplexing detection of IgG against Plasmodium falciparum pregnancy-specific antigens

PLos ONE; 12 (7), 2017

Background: Pregnant women exposed to Plasmodium falciparum generate antibodies against VAR2CSA, the parasite protein that mediates adhesion of infected erythrocytes to the placenta. There is a need of high-throughput tools to determine the fine specificity of these antibodies that can be used to identif...