Results: 18

Performance of two plasma separation devices for HIV-1 viral load measurement in primary healthcare settings

Microbiol. spectr; 11 (6), 2023
ABSTRACT Dried blood spot (DBS) may overestimate the viral RNA, mainly in patients with low viral load (VL), due to proviral DNA and intracellular RNA. The Burnett and HemaSpot provide integrated solutions for the collection, separation, and drying of plasma from whole blood. This study aims to evalua...

Managers’ and providers’ perspectives on barriers and facilitators for the implementation of differentiated service delivery models for HIV treatment in Mozambique: a qualitative study

J. int. aids soc; 26 (3), 2023
In 2018, Mozambique's Ministry of Health launched a guideline for a nationwide implementation of eight differentiated service delivery models to optimize HIV service delivery and achieve universal coverage of HIV care and treatment. The models were (1) Fast‐track, (2) Three‐month Antiretrovirals Disp...

Reduced Placental Transfer of Antibodies Against a Wide Range of Microbial and Vaccine Antigens in HIV-Infected Women in Mozambique

Front. immunol; 12 (), 2021
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...

Usability and Feasibility of an Innovative mLearning Approach for Nurses Providing Option B+ Services in Manica and Sofala Provinces, Mozambique

The scaling of Option B+ services, whereby all pregnant women who test HIV positive are started on lifelong antiretroviral therapy upon diagnosis regardless of CD4 T-cell count, is ongoing in many high HIV burden, low-resource countries. We developed and evaluated a tablet-based mobile learning (mLearnin...

Immunodeficiency at antiretroviral therapy start: five-Year adult data (2012-2017) based on evolving national policies in rural mozambique

AIDS res. hum. retrovir; 36 (1), 2020
Before the 2015 implementation of "Test and Start," the initiation of combination antiretroviral therapy (ART) was guided by specific CD4 cell count thresholds. As scale-up efforts progress, the prevalence of advanced HIV disease at ART initiation is expected to decline. We analyzed the temporal trends i...

Desafios para a Adesão ao TARV na Perspectiva dos Profissionais do Sistema de Saúde de Moçambique

Resumo O objetivo do estudo foi compreender quais são os principais desafios para adesão ao tratamento antirretroviral em Moçambique na perspectiva dos profissionais de saúde que lidam com a temática do HIV/aids no país. O estudo é qualitativo, observacional e exploratório. Entrevistas semiestrut...

Mozambique’s Community Antiretroviral Therapy Support Group Program: The Role of Social Relationships in Facilitating HIV/ AIDS Treatment Retention

AIDS behav; 23 (9), 2019
The Community Antiretroviral (ARV) Therapy Support Group (CASG) program aims to address low retention rates in Mozambique’s HIV treatment program and the absorptive capacity of the country’s health facilities. CASG provides patients with the opportunity to form groups, whose members provide peer supp...

Taxa de abandono do tratamento antirretroviral (TARV) e seus fatores associados em pacientes adultos inscritos no Centro de Saúde de Namacurra – Sede, no período de 1 de janeiro 2015 a 31 de dezembro 2016, na província da Zambézia, em Moçambique
Taxa de abandono do tratamento antirretroviral (TARV) e seus fatores associados em pacientes adultos inscritos no Centro de Saúde de Namacurra – Sede, no período de 1 de janeiro 2015 a 31 de dezembro 2016, na província da Zambézia, em Moçambique

O Vírus de Imunodeficiência Humana (VIH) e Síndroma de Imunodeficiência Adquirida (SIDA) continuam sendo um dos graves problemas de saúde pública. A terapia antirretroviral (TARV) veio para a melhoria da qualidade de vida, aumento da sobrevida dos pacientes infetados, mas o desafio da adesão é ba...

Tuberculosis Case Finding With Combined Rapid Point-of-Care Assays (Xpert MTB/RIF and Determine TB LAM) in HIV-Positive Individuals Starting Antiretroviral Therapy in Mozambique

Clin. infect. dis; 65 (11), 2017
Tuberculosis is a major health concern in several countries, and effective diagnostic algorithms for use in human immunodeficiency virus (HIV)–positive patients are urgently needed. Methods. At prescription of antiretroviral therapy, all patients in 3 Mozambican health centers were screened for tubercu...

Performance characteristics of finger-stick dried blood spots (DBS) on the determination of human immunodeficiency virus (HIV) treatment failure in a pediatric population in Mozambique

PLos ONE; 12 (7), 2017
Quantitative plasma viral load (VL) at 1000 copies /mL was recommended as the threshold to confirm antiretroviral therapy (ART) failure by the World Health Organization (WHO). Because of ongoing challenges of using plasma for VL testing in resource-limited settings (RLS), especially for children, this st...