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HIV drug resistance patterns in pregnant women using next generation sequence in Mozambique

Rupérez, María; Julian, Marc Noguera; González, Raquel; Maculuve, Sonia; Bellido, Rocío; Vala, Anifa; Rodríguez, Cristina; Sevene, Esperança; Paredes, Roger; Menéndez, Clara.
PLos ONE; 13 (5), 2018
Background: Few data on HIV resistance in pregnancy are available from Mozambique, one of the countries with the highest HIV toll worldwide. Understanding the patterns of HIV drug resistance in pregnant women might help in tailoring optimal regimens for prevention of mother to child transmission of HIV (...
Anti-HIV Agents/administration & dosage, CD4 Lymphocyte Count/methods, Drug Resistance, Viral, HIV Infections/drug therapy, Drug Resistance, Viral/drug effects, Infectious Disease Transmission, Vertical/prevention & control, Pregnancy Complications, Infectious/drug therapy, Mozambique, Prenatal Care/methods, HIV-1/chemistry
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The clinical and economic impact of point-of-care CD4 testing in mozambique and other resource-limited settings: a cost-effectiveness analysis

Hyle, emily, p; Jani, ilesh, v; Lehe, jonathan; Su, amanda, e; Wood, robin; Quevedo, jorge; Losina, elena; Bassett, ingrid, v; Pei, pamela, p; Paltiel, a, david; Resch, stephen; Freedberg, kenneth, a; Peter, trevor; Walensky, rochelle, p.
PloS med; 11 (9), 2014
Background: Point-of-care CD4 tests at HIV diagnosis could improve linkage to care in resource-limited settings. Our objective is to evaluate the clinical and economic impact of point-of-care CD4 tests compared to laboratory-based tests in Mozambique. Methods and findings: We use a validated model of HIV...
CD4 Lymphocyte Count/economics, CD4 Lymphocyte Count/methods, Cost-Benefit Analysis/economics, Cost-Benefit Analysis/methods, HIV Infections/diagnosis, HIV Infections/epidemiology, HIV Infections/economics, Health Care Costs, Health Resources/economics, Mozambique/epidemiology, Point-of-Care Systems/economics
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Performance of the PointCare NOW system for CD4 counting in HIV patients based on five independent evaluations

Bergeron, michèle; Daneau, géraldine; Ding, tao; Sitoe, Nádia; Westerman, larry, e; Stokx, jocelijn; Jani, ilesh, v; Coetzee, lindi, m; Scott, lesley; Weggheleire, anja de; Boel, Luc; Stevens, wendy, s; Glencross, deborah; Peter, trevor, f.
PLos ONE; 7 (8), 2012
Introduction: Point-of-care (POC) CD4 testing can improve access to treatment by enabling decentralization and reducing patient loss-to-follow-up. As new POC CD4 technologies become available, their performance should be assessed before widespread deployment. This study reports the findings of five indep...
CD4 Antigens, HIV/drug effects, Anti-HIV Agents, CD4 Lymphocyte Count/methods, HIV Infections/immunology, Eligibility Determination, CD4 Lymphocyte Count/trends, Quality Control, Answering Services
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