Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae in children with acute bacterial meningitis in Mozambique: implications for a national immunization strategy
BMC microbiol; 16 (1), 2016
Background: S. pneumoniae is the leading cause of acute bacterial meningitis (ABM) in children. Vaccination using the 10-valent conjugate vaccine (PCV-10) was recently introduced into the National Immunization Program in Mozambique, but data on serotype coverage of this vaccine formulation are scarce. In...
Anti-Bacterial Agents/pharmacology, Pneumococcal Vaccines, DNA, Bacterial/analysis, Ceftriaxone/pharmacology, Microbial Sensitivity Tests, Drug Resistance, Multiple, Bacterial, Epidemiological Monitoring, Meningitis, Bacterial/epidemiology, Meningitis, Bacterial/microbiology, Meningitis, Bacterial/prevention & control, Penicillins/pharmacology, Pneumococcal Infections/immunology, Pneumococcal Infections/microbiology, Pneumococcal Vaccines/administration & dosage, Streptococcus pneumoniae/classification, Streptococcus pneumoniae/genetics, Streptococcus pneumoniae/isolation & purification, Streptococcus pneumoniae/radiation effects, Polymerase Chain Reaction, Mozambique/epidemiology