Placental Microparticles and MicroRNAs in Pregnant Women with Plasmodium falciparum or HIV Infection
PLos ONE; 11 (1), 2016
During pregnancy, syncytiotrophoblast vesicles contribute to maternal tolerance towards the fetus, but also to pathologies such as pre-eclampsia. The aim of the study was to address whether Plasmodium falciparum and HIV infections in pregnancy affect the secretion, microRNA content and function of tropho...
Malaria, Falciparum/pathology, Malaria, Falciparum/metabolism, Placenta/metabolism, Pregnancy Outcome, Cell-Derived Microparticles/metabolism, Cell-Derived Microparticles/ultrastructure, Chemokines/metabolism, Dendritic Cells/metabolism, Demography/statistics & numerical data, Infant, Newborn, MicroRNAs/metabolism, Plasmodium falciparum/physiology, Trophoblasts/metabolism, Mozambique