Yan, tingting;
Mullany, Luke C;
Subedi, Seema;
Haze, Elizabeth A;
Khatry, Subarna K;
Mohan, Diwakar;
Zeger, Scott;
Tielsch, James M;
LeClerq , Steven C;
Katz, Joanne.
Objectives: To assess the association between maternal characteristics, adverse birth outcomes (small-for-gestational-age (SGA) and/or preterm) and neonatal mortality in rural Nepal.
Design: This is a secondary observational analysis to identify risk factors for neonatal mortality, using data from a rand...
Levy, karen;
Garn, joshua V;
Cumbe, zaida adriano;
Muneme, bacelar;
Fagnant-Sperati, christine s;
Hubbard, Sydney;
Júnior, antonio;
Manuel, joão luís;
Mangamela, Magalhães;
McGunegill, sandy;
Miller-Petrie, molly k;
Snyder, jedidiah s;
Victor, courtney;
Waller, lance a;
Konstantinidis, konstantinos t;
Clasen, thomas f;
Brown, joe;
Nalá, rassul;
Freeman, matthew c.
Introduction: Despite clear linkages between provision of clean water and improvements in child health, limited information exists about the health impacts of large water infrastructure improvements in low-income settings. Billions of dollars are spent annually to improve urban water supply, and rigorou...
Water Supply/methods,
Cohort Studies,
Ethics Committees, Research,
Gastrointestinal Microbiome,
Humans,
Infant,
Mozambique,
Pregnancy,
Prospective Studies,
Waterborne Diseases/transmission,
d0148810
Dados do Programa Conjunto das Nações Unidas para HIV/SIDA (ONUSIDA), estimam que, em 2018, 2.2 milhões de pessoas viviam com HIV (PVHIV). Destas, 56% faziam Tratamento Antirretroviral (TARV) e apenas 45% estavam em supressão viral (< 1000 cópias/mL). Vários são os factores que podem estar associa...
Background: Technological advances and high throughput biological assays can facilitate discovery science in biobanks from population cohorts, including pregnant women. Biological pathways associated with health outcomes differ depending on geography, and high-income country data may not generalise to lo...
Em 2018 Moçambique contava com cerca de 2.2 milhões de pessoas vivendo com HIV (PVHIV), e destas 55% (1.212.562) eram pacientes activos em Tratamento Antiretroviral (TARV), segundo as estimativas de modelagem do Programa Conjunto das Nações Unidas para HIV/SIDA (ONUSIDA) de 2019.
Um dos maiores desaf...
Soro, Laura Fuente;
Varela, Elisa López;
Augusto, Orvalho;
Bernardo, Edson Luis;
Sacoor, Charfudin;
Nhacolo, Ariel;
Castillo, Paula Ruiz;
Alfredo, Charity;
Karajeanes, Esmeralda;
Vaz, Paula;
Naniche, Denise.
Patients lost to follow-up (LTFU) over the human immunodeficiency virus (HIV) cascade have poor clinical outcomes and contribute to onward HIV transmission. We assessed true care outcomes and factors associated with successful reengagement in patients LTFU in southern Mozambique.
Newly diagnosed HIV-posi...
Kovacs, stephanie d;
Eijk, anna maria van;
Sevene, esperanca;
Dellicour, stephanie;
Weiss, noel, s;
Emerson, scott;
Steketee, richard;
Kuile, feiko O. ter;
Stergachis, andy.
Given the high morbidity for mother and fetus associated with malaria in pregnancy, safe and efficacious drugs are needed for treatment. Artemisinin derivatives are the most effective antimalarials, but are associated with teratogenic and embryotoxic effects in animal models when used in early pregnancy....
Abortion, Spontaneous,
Antimalarials/adverse effects,
Antimalarials/therapeutic use,
Artemisinins/adverse effects,
Artemisinins/therapeutic use,
Cohort Studies,
Malaria/drug therapy,
Pregnancy Complications, Parasitic/drug therapy,
Malaria
After the decrease in clinical malaria incidence observed in Mozambique until 2009, a steady resurgence of cases per year has been reported nationally, reaching alarming levels in 2014. However, little is known about the clinical profile of the cases presented, or the possible epidemiological factors con...
Mozambique,
Epidemiology,
Cohort Studies,
Fever,
Incidence,
Malaria,
Outpatients,
Analysis of Variance,
Seasons,
Hospitals,
Plasmodium falciparum,
Age Distribution,
Adult Children
A WHO-supported provincial-level population-based survey was conducted in 2007 to understand the determinants and implications for health of vaginal practices. A total of 919 women aged 18-60 were selected randomly for enrolment. This is the first population-based study of females in Tete Province, Mozam...
Sexual Health,
Reproductive Health/statistics & numerical data,
Sexually Transmitted Diseases,
Cohort Studies,
Surveys and Questionnaires/statistics & numerical data,
Family,
Foraminifera/microbiology,
Condoms/trends,
Abdominal Pain/parasitology,
Mozambique/epidemiology,
HIV Testing/statistics & numerical data
Tint, Halidou;
Seveno, Esperança;
Dellicour, Stephanie;
Calip, Gregory S;
D'Alessandro, Umberto;
Macete, Eusébio;
Diallo , Seydou Nakanabo;
Kazienga, Adama;
Valea, Innocent;
Sorgho, Hermann;
Valá, Anifa;
Augusto, Orvalho;
Ruperez, Clara;
Menendez, Clara;
Ouma, Peter;
Desai, Meghna;
Kuile, Feiko Ter;
Stergachis, Andy.
Background: A major unresolved safety concern for malaria case management is the use of artemisinin combination therapies (ACTs) in the first trimester of pregnancy. There is a need for human data to inform policy makers and treatment guidelines on the safety of artemisinin combination therapies (ACT) wh...
Antimalarials/adverse effects,
Artemisinins/adverse effects,
Clinical Protocols,
Cohort Studies,
Drug Administration Schedule,
Gestational Age,
Malaria/therapy,
Maternal-Fetal Exchange,
Patient Selection,
Pharmacovigilance,
Pregnancy Complications, Parasitic/therapy,
Pregnancy Outcome,
Pregnancy Trimester, First,
Prenatal Exposure Delayed Effects,
Prospective Studies,
Research Design,
Sample Size,
Mozambique,
Burkina Faso,
Kenya,
Antimalarials/therapeutic use,
Artemisinins/therapeutic use
