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Field performance of ultrasensitive and conventional malaria rapid diagnostic tests in southern Mozambique

Galatas, Beatriz; Mayor, Alfredo; Gupta, Himanshu; Balanza, Núria; Jang, Ihn Kyung; Nhamussua, Lidia; Simone, Wilson; Cistero, Pau; Chidimatembue, Arlindo; Munguambe, Humberto; Saute, Francisco; Aide, Pedro; Bassat, Quique.
Malar. j. (Online); 19 (1), 2020
An ultrasensitive malaria rapid diagnostic test (RDT) was recently developed for the improved detection of low-density Plasmodium falciparum infections. This study aimed to compare the diagnostic performance of the PfHRP2-based Abbott Malaria Ag P. falciparum ultrasensitive RDT (uRDT) to that of the conv...
Antigens, Protozoan/genetics, Parasitology/methods, d0077700, d0126800, Mozambique, Antigens, Protozoan/blood, Cross-Sectional Studies, Dried Blood Spot Testing/methods, Dried Blood Spot Testing/statistics & numerical data, Malaria, Falciparum/diagnosis, Parasitology/statistics & numerical data, Plasmodium falciparum/genetics
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Multiplexing detection of IgG against Plasmodium falciparum pregnancy-specific antigens

Fonseca, ana maria; Quinto, llorenç; Jiménez, alfons; González, raquel; Bardají, azucena; Maculuve, sonia; Dobaño, carlota; Rupérez, maria; Vala, anifa; Aponte, john, j; Sevene, esperanza; Macete, Eusebio; Menéndez, clara; Mayor, alfredo.
PLos ONE; 12 (7), 2017
Background: Pregnant women exposed to Plasmodium falciparum generate antibodies against VAR2CSA, the parasite protein that mediates adhesion of infected erythrocytes to the placenta. There is a need of high-throughput tools to determine the fine specificity of these antibodies that can be used to identif...
Antibodies, Protozoan/blood, Antibodies, Protozoan/immunology, Antigens, Protozoan/genetics, Antigens, Protozoan/immunology, Antigens, Protozoan/metabolism, Dried Blood Spot Testing, Erythrocytes/parasitology, Immunoassay, Immunoglobulin G/blood, Malaria, Falciparum/diagnosis, Plasmodium falciparum/isolation & purification, Pregnancy
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Evaluation of a High-Throughput Diagnostic System for Detection of HIV-1 in Dried Blood Spot Samples from Infants in Mozambique

Jani, Ilesh; Sebastian, Jennifer; Vubil, Adolfo; Subbarao, Shambavi; Bila, Dolce; Sousa, Amina; Mabunda, Nédio; Garcia, Albert; Ellemberger, Dennis; Ramos, Artur; Skaggs, Beth.
J. clin. microbiol; 50 (4), 2012
We performed a comparative analysis between Roche Amplicor HIV-1 DNA test and CAPTAQ assay for the detection of HIV in 830 dried blood spot (DBS) pediatric samples collected in Mozambique. Our results demonstrated no statistical difference between these assays. The CAPTAQ assay approached nearly 100% rep...
HIV Infections/diagnosis, HIV Infections/blood, Dried Blood Spot Testing/methods, Mozambique, HIV-1/genetics, Molecular Diagnostic Techniques, Reproducibility of Results, Sensitivity and Specificity
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