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Molecular surveillance for polymorphisms associated with artemisinin-based combination therapy resistance in Plasmodium falciparum isolates collected in Mozambique, 2018

Chidimatembue, arlindo; Svigel, samaly s.
Malar. j. (Online); 20 (1), 2021
Background: Due to the threat of emerging anti-malarial resistance, the World Health Organization recommends incorporating surveillance for molecular markers of anti-malarial resistance into routine therapeutic efficacy studies (TESs). In 2018, a TES of artemether-lumefantrine (AL) and artesunate-amodiaq...
Antimalarials/pharmacology, Antimalarials/therapeutic use, Artemisinins/pharmacology, Artemisinins/therapeutic use, Drug Resistance/genetics, Drug Therapy, Combination, Genetic Markers, Plasmodium falciparum/radiation effects, Plasmodium falciparum/genetics, Plasmodium falciparum/isolation & purification, Polymorphism, Genetic/genetics, Mozambique
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Immunodeficiency at antiretroviral therapy start: five-Year adult data (2012-2017) based on evolving national policies in rural mozambique

Arinze, folasade; Gong, wu; Green, ann f; Schacht, caroline de; Carlucci, james g; Silva, wilson; Claquin, gael; Tique, josé a; Stefanutto, marzio; Graves, erin; Rompaey, sara van; Alvim, maria fernanda sardella; Tomo, simão; Moon, troy d; Wester, william.
AIDS res. hum. retrovir; 36 (1), 2020
Before the 2015 implementation of "Test and Start," the initiation of combination antiretroviral therapy (ART) was guided by specific CD4 cell count thresholds. As scale-up efforts progress, the prevalence of advanced HIV disease at ART initiation is expected to decline. We analyzed the temporal trends i...
Anti-HIV Agents/therapeutic use, Health Policy, Immunologic Deficiency Syndromes/epidemiology, Drug Therapy, Combination, Rural Population, Mozambique/epidemiology, Antiretroviral Therapy, Highly Active, d0066780
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