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Multiplexing detection of IgG against Plasmodium falciparum pregnancy-specific antigens

Fonseca, ana maria; Quinto, llorenç; Jiménez, alfons; González, raquel; Bardají, azucena; Maculuve, sonia; Dobaño, carlota; Rupérez, maria; Vala, anifa; Aponte, john, j; Sevene, esperanza; Macete, Eusebio; Menéndez, clara; Mayor, alfredo.
PLos ONE; 12 (7), 2017
Background: Pregnant women exposed to Plasmodium falciparum generate antibodies against VAR2CSA, the parasite protein that mediates adhesion of infected erythrocytes to the placenta. There is a need of high-throughput tools to determine the fine specificity of these antibodies that can be used to identif...
Antibodies, Protozoan/blood, Antibodies, Protozoan/immunology, Antigens, Protozoan/genetics, Antigens, Protozoan/immunology, Antigens, Protozoan/metabolism, Dried Blood Spot Testing, Erythrocytes/parasitology, Immunoassay, Immunoglobulin G/blood, Malaria, Falciparum/diagnosis, Plasmodium falciparum/isolation & purification, Pregnancy
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Impact of age of first exposure to Plasmodium falciparum on antibody responses to malaria in children: a randomized, controlled trial in Mozambique

Nhabomba, augusto J; Guinovart, caterina; Dobaño, carlota; Alonso, pedro L; Chitnis, chetan E; Mayor, alfredo; Aponte, john J; Bassat, quique; Rodríguez, mauricio H; Barbosa, arnoldo; Aguila, ruth; Cisteró, pau; Quintó, llorenç; Manaca, maria N; Jiménez, alfons.
Malar. j. (Online); 13 (121), 2014
Background: The impact of the age of first Plasmodium falciparum infection on the rate of acquisition of immunity to malaria and on the immune correlates of protection has proven difficult to elucidate. A randomized, double-blind, placebo-controlled trial using monthly chemoprophylaxis with sulphadoxine-...
Malaria, Falciparum/immunology, Mozambique/epidemiology, Pyrimethamine/therapeutic use, Sulfadoxine/therapeutic use, Adaptive Immunity, Antigens, Protozoan/immunology, Environmental Exposure, Malaria, Falciparum/prevention & control, Malaria, Falciparum/epidemiology, Malaria, Falciparum/parasitology, Enzyme-Linked Immunosorbent Assay, Erythrocytes/parasitology, Erythrocytes/immunology, Chemoprevention
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