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HIV infection and placental malaria reduce maternal transfer of multiple antimalarial antibodies in Mozambican women
HIV infection and placental malaria reduce maternal transfer of multiple antimalarial antibodies in Mozambican women

Alonso, Selena; Vidal, Marta; Olalla, Gemma Ruiz; Gonzalez, Raquel; Jairoce, Chenjerai; Manaca, M Nelia; Santiago, Miquel Vázquez; Balcells, Reyes; Vala, Anifa; Ruperez, María; Cistero, Pau; Soro, Laura Fuente; Angov, Evelina 5; Coppel, Ross L 6; Geimain, Benoit; Cavanagh, David; Beeson, James G; Nhacolo, Arsenio; Sevene, Esperança; Aponte, John J; Macete, Eusébio; Aguilar, Ruth; Mayor, Alfredo; Menendez, Clara; Dobano, Carlota; Moncunill, Gemma.
J. infect; 82 (4), 2021
Maternal Plasmodium falciparum-specific antibodies may contribute to protect infants against severe malaria. Our main objective was to evaluate the impact of maternal HIV infection and placental malaria on the cord blood levels and efficiency of placental transfer of IgG and IgG subclasses. Methods: In ...
Fetal Blood, HIV, Immunoglobulin G, Schools, Nursery, Malaria
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Reduced Placental Transfer of Antibodies Against a Wide Range of Microbial and Vaccine Antigens in HIV-Infected Women in Mozambique

Alonso, Selena; Vudal, Marta; Olalla, Gemma Ruiz; Gonzelez, Raquel; Manaca, M Nelia; Jairoce, Chenjerai; Balcells, Reyes; Vala, Anifa; Ruperez, María; Soro, Laura Fuente; Cova, Marta; Angov, Evelina; Nhacolo, Arsenio; Sevene, Esperança; Aponte, John J; Macete, Eusebio; Dobano, Carlota; Moncunil, Gemma.
Front. immunol; 12 (), 2021
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...
Antibodies/immunology, Antigens/immunology, Antiretroviral Therapy, Highly Active, Fetal Blood/immunology, HIV Infections/therapy, HIV Infections/epidemiology, HIV Infections/immunology, HIV Infections/virology, Immunity, Maternally-Acquired, Immunoglobulin G/immunology, Maternal-Fetal Exchange/immunology, Placenta/metabolism, Pregnancy, Carrier Proteins, Sex Factors, Vaccines/immunology
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