Jofrin, léa;
Goodman, steven m;
Wilkinson, david a;
Ramasindrazana, beza;
Lagadec, erwan;
Minter, gildas le;
Santos, andréa dos;
Schoeman, m corrie;
Sookhareea, rajendraprasad;
Tortosa, Pablo;
Gudo, eduardo s;
Mavingui, Patrick;
Lebarbenchon, camille.
Bats provide key ecosystem services such as crop pest regulation, pollination, seed dispersal, and soil fertilization. Bats are also major hosts for biological agents responsible for zoonoses, such as coronaviruses (CoVs). The islands of the Western Indian Ocean are identified as a major biodiversity hot...
Mozambique,
Prevalence,
Indian Ocean Islands/epidemiology,
Social Control, Formal,
Coronavirus Infections/epidemiology,
Coronavirus Infections/veterinary,
Coronavirus Infections/virology,
DNA, Viral/genetics,
Ecosystem,
Evolution, Molecular,
Genetic Variation,
Host Specificity,
Phylogeny,
Mass Screening,
Phylogeography/methods,
RNA-Dependent RNA Polymerase,
Alphacoronavirus/genetics,
Betacoronavirus/genetics,
Chiroptera/virology,
RNA-Dependent RNA Polymerase/genetics,
Real-Time Polymerase Chain Reaction,
Zoonoses/epidemiology,
Zoonoses/virology
Perdigão, joão;
Silva, carla;
Diniz, jaciara;
Pereira, catarina;
Machado, diana;
Ramos, jorge;
Silva, hugo;
Abilleira, fernanda;
Brum, clarice;
Reis, Ana, J.
Tuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tube...
Bacterial Typing Techniques,
Databases, Genetic,
Genetic Variation,
Microsatellite Repeats,
Molecular Epidemiology,
Mozambique/epidemiology,
Mycobacterium tuberculosis/genetics,
Tuberculosis, Multidrug-Resistant/epidemiology,
Tuberculosis, Multidrug-Resistant/microbiology,
Tuberculosis, Multidrug-Resistant/transmission
Joao, eva dora;
Stroydon, amey;
Oneil g, hester;
Cumba, assa;
Cossecera, marta;
Acacio, sozinho;
Mandomando, inácio;
Motanyane, lithabiso;
Page, nicola;
Deus, nilsa de.
In Mozambique rotavirus (RV) was shown to be the greatest cause of acute diarrhoea in infants from 0 to 11 months, and in 2015, national rotavirus vaccination was introduced. As with other developing countries, there is very limited active strain characterisation. Rotavirus positive clinical specimens, c...
Gastroenteritis/virology,
Genotype,
Rotavirus Infections/virology,
Acute Disease,
Phylogeny,
Rotavirus/genetics,
Antigens, Viral/genetics,
Genetic Variation,
Gene Expression Regulation, Viral,
Mozambique,
Epitopes/genetics
A diversidade genética do Plasmodium falciparum é um dos maiores obstáculos para o desenvolvimento da imunidade assim como para a eficácia terapêutica de antimaláricos, pois confere ao parasita habilidade para evadir a resposta imune do hospedeiro, gerando mudanças na sua composição antigénica,...
As infecções pelo Plasmodium falciparum (P.falciparum) e pelo Vírus da Imunodeficiência Humana (HIV) constituem problema de Saúde Pública particularmente na África subsaariana onde as duas infecções têm o seu maior peso. A sobreposição geográfica das duas infecções implica a ocorrência da...
Plasmodium falciparum,
HIV Infections,
Malaria/complications,
Malaria/diagnosis,
Patients,
T-Lymphocytopenia, Idiopathic CD4-Positive,
Genetic Variation,
Merozoites,
Mozambique,
Antimalarials/immunology,
CD4 Antigens
Oliveira, Michelli, F;
Ramalho, Dulce, B;
Abreu, Celina, M;
Vubil, Adolfo Salvador;
Mabunda, Nédio;
Ismael, Nalia;
Francisco, Cidia;
Jani, Ilesh, V;
Tanuri, Amilcar.
HIV proviral DNA integration into the host chromosome is carried out by integrase becoming an important target antiretroviral therapy. Raltegravir was the first integrase inhibitor approved for use in HIV therapy and elvitegravir is in the late phase of clinical development; both show good results in mon...
DNA, Viral/genetics,
HIV-1,
DNA, Viral/chemistry,
Mozambique,
Drug Resistance, Viral,
Genetic Variation,
HIV Infections/virology,
HIV Integrase/genetics,
Molecular Sequence Data,
Mutation,
Proviruses/genetics,
Sequence Analysis, DNA
Viegas, sofia omar;
Machado, adelina;
Groenheit, Ramona;
Ghebremichael, solomon;
Pennhag, alexandra;
Gudo, paula, s;
Cuna, zaina;
Langa, egídio;
Miotto, paolo;
Cirillo, Daniela, M.
Background: Mozambique is one of the countries with the highest burden of tuberculosis (TB) in Sub-Saharan Africa, and information on the predominant genotypes of Mycobacterium tuberculosis circulating in the country are important to better understand the epidemic. This study determined the predominant s...
A tuberculose é a principal causa de morte no mundo entre as doenças infecciosas, produzindo 2 milhões de óbitos ao ano. Estima-se que um terço da população mundial esteja infectada pelo Mycobacterium tuberculosis, ou seja, 1,7 bilhões de pessoas. Em países africanos, o problema da tuberculose e...
Mycobacterium tuberculosis,
HIV Infections,
Genetic Variation,
Polymerase Chain Reaction,
Cause of Death,
Communicable Diseases,
Risk Factors,
HIV,
Incidence,
Acquired Immunodeficiency Syndrome,
Patient Isolation
Chilaúle, Jorfélia J;
Munlela, Benilde;
Mans, Janet;
Mabasa, Victor V;
Marques, Selma;
Bauhofer, Adilson Fernando Loforte;
Jane, Graziela;
Anapakala, Elda;
Oliveira, Fernanda;
Moiane, Idalécia Cossa;
Guimarães, Esperança;
Sambo, Júlia.
Norovirus (NoV) is the second most important cause of viral diarrheal disease in children worldwide after rotavirus and is estimated to be responsible for 17% of acute diarrhea in low-income countries. This study aimed to identify and report NoV genotypes in Mozambican children under the age of five year...
Caliciviridae Infections/epidemiology,
Diarrhea/epidemiology,
Feces,
Gastroenteritis,
Genetic Variation,
Genotype,
Norovirus/genetics,
Phylogeny,
RNA-Dependent RNA Polymerase,
RNA-Directed DNA Polymerase/genetics,
Mozambique/epidemiology
