Bauhofer, Adilson Fernando Loforte;
Ussivane, Édio Ussivane;
Chissaque, Assucênio Chissaque;
Iahaia, Fátima Iahaia;
Pololo, Ramígio;
Campos, Fernanda;
Miranda, Emerson;
António, Luciana;
Maholela, Placida;
Gatambire, Aline;
Djedje, Marlene;
Raice, Fatima;
Goncalves, Luzia;
Deus, Nilza;
Inlamea, Osvaldo.
Background: Seroprevalence studies provide information on the true extent of infection and capture demographic and geographic differences, indicating the level of immunity against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). We sought to provide local evidence of SARS-CoV-2 exposure in s...
Antibodies, Viral/blood,
COVID-19/epidemiology,
COVID-19/immunology,
Cross-Sectional Studies,
Immunoglobulin G/blood,
Immunoglobulin M,
Mozambique/epidemiology,
Prevalence,
SARS-CoV-2/immunology,
Schools,
Seroepidemiologic Studies
Arnaldo, Paulo;
Mabunda, Nédio;
Wesley Young, Peter;
Tran, Tiffany;
Sitoe, Nádia;
Chelene, Imelda;
Nhanombe, Armando;
Ismael, Nália;
Júnior, António;
Cubula, Basílio;
Frederico Inlamea, Osvaldo;
Gudo, Eduardo;
Jani, Ilesh Vinodrai.
The extent of population exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was uncertain in many African countries during the onset of the pandemic.
Methods: We conducted a cross-sectional study and randomly selected and surveyed general population and occupational groups from 6 J...
Arnaldo, Paulo;
Mabunda, Nédio;
Young, Peter Wesley;
Tran, Tiffany;
Sitoe, Nádia;
Chelene, Imelda;
Nhanombe, Armando;
Ismael, Nália;
Júnior, António;
Cubula, Basílio;
Inlamea, Osvaldo Frederico;
Gudo, Eduardo;
Jani, Ilesh Vinodrai.
Background
The extent of population exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was uncertain in many African countries during the onset of the pandemic.
Methods
We conducted a cross-sectional study and randomly selected and surveyed general population and occupational groups...
Occupational Groups,
Antibodies,
Severe Acute Respiratory Syndrome,
Seroepidemiologic Studies,
COVID-19/epidemiology,
Mozambique/epidemiology,
COVID-19 Testing,
Cross-Sectional Studies/methods,
Immunoglobulin G/immunology,
Immunoglobulin M,
SARS-CoV-2/growth & development,
Coronavirus
Alonso, Selena;
Vidal, Marta;
Olalla, Gemma Ruiz;
Gonzalez, Raquel;
Jairoce, Chenjerai;
Manaca, M Nelia;
Santiago, Miquel Vázquez;
Balcells, Reyes;
Vala, Anifa;
Ruperez, María;
Cistero, Pau;
Soro, Laura Fuente;
Angov, Evelina 5;
Coppel, Ross L 6;
Geimain, Benoit;
Cavanagh, David;
Beeson, James G;
Nhacolo, Arsenio;
Sevene, Esperança;
Aponte, John J;
Macete, Eusébio;
Aguilar, Ruth;
Mayor, Alfredo;
Menendez, Clara;
Dobano, Carlota;
Moncunill, Gemma.
Maternal Plasmodium falciparum-specific antibodies may contribute to protect infants against severe malaria. Our main objective was to evaluate the impact of maternal HIV infection and placental malaria on the cord blood levels and efficiency of placental transfer of IgG and IgG subclasses.
Methods: In ...
Alonso, Selena;
Vudal, Marta;
Olalla, Gemma Ruiz;
Gonzelez, Raquel;
Manaca, M. Nelia;
Jairoce, Chenjerai;
Santiago, Chenjerai;
Balcells, Reyes;
Vala, Anifa;
Ruperez, María;
Cistero, Pau;
Soro, Laura Fuente;
Cova, Marta;
Angov, Evelina;
Nhacolo, Arsenio;
Sevene, Esperança;
Aponte, John J;
Macete, Eusebio;
Aguilar, Ruth;
Mayor, Alfredo;
Menendez, Clara;
Dobano, Carlota;
Moncunil, Gemma.
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...
HIV,
Immunoglobulin G,
Antibodies, Monoclonal,
Malaria,
Schools, Nursery,
Blood-Borne Pathogens,
d0053120,
Placenta/immunology,
Placenta/metabolism,
Pregnancy,
HIV Infections/virology
Alonso, Selena;
Vudal, Marta;
Olalla, Gemma Ruiz;
Gonzelez, Raquel;
Manaca, M Nelia;
Jairoce, Chenjerai;
Balcells, Reyes;
Vala, Anifa;
Ruperez, María;
Soro, Laura Fuente;
Cova, Marta;
Angov, Evelina;
Nhacolo, Arsenio;
Sevene, Esperança;
Aponte, John J;
Macete, Eusebio;
Dobano, Carlota;
Moncunil, Gemma.
Transplacental transfer of antibodies is essential for conferring protection in newborns against infectious diseases. We assessed the impact of different factors, including gestational age and maternal infections such as HIV and malaria, on the efficiency of cord blood levels and placental transfer of Ig...
Antibodies/immunology,
Antigens/immunology,
Antiretroviral Therapy, Highly Active,
Fetal Blood/immunology,
HIV Infections/therapy,
HIV Infections/epidemiology,
HIV Infections/immunology,
HIV Infections/virology,
Immunity, Maternally-Acquired,
Immunoglobulin G/immunology,
Maternal-Fetal Exchange/immunology,
Placenta/metabolism,
Pregnancy,
Carrier Proteins,
Sex Factors,
Vaccines/immunology
Toxoplasmosis is a parasitic zoonotic disease caused by Toxoplasma gondii that afflicts humans worldwide and wild and domestic warm-blooded animals. In immunocompetent individuals, the acute phase of infection presents transient low or mild symptoms that remain unnoticed. In immunocompromised patients, T...
Antibodies, Protozoan/blood,
Biomedical Research/trends,
Immunocompromised Host,
Pregnancy Complications, Parasitic/epidemiology,
Toxoplasma/genetics,
Immunoglobulin G/blood,
Zoonoses/epidemiology,
Risk Factors,
Mozambique/epidemiology,
Toxoplasma/pathogenicity,
Toxoplasmosis/complications,
Toxoplasmosis/epidemiology,
Toxoplasmosis, Congenital/epidemiology
Antonio, virgilio santo;
Monteiro, vanessa;
Amade, nadia alves;
Muianga, argentina felisbela;
Mula, flora;
Chelene, imelda;
Ali, sadia;
Oludele, john;
Chongo, Inocêncio;
Jose, americo;
Augusto, orvalho;
Samo Gudo, eduardo.
Introduction: Longitudinal data and trends about chikungunya virus (CHIKV) are critical for its control, however in Mozambique very few studies were conducted over 5 decades, between 1957 and 2013. In this study, we retrospectively investigated the occurrence, geographical distribution and trend of anti-...
Watchful Waiting,
Chikungunya virus,
Serum,
Similar,
Measles,
Rubella,
Mass Screening,
Patients,
Methods,
Immunoglobulin M,
Immunoglobulin G,
Age Groups,
51607,
Enzyme-Linked Immunosorbent Assay,
Antibodies,
Measles/prevention & control,
Mozambique
Mayor, alfredo;
Dobaño, carlota;
Nhabomba, augusto;
Guinovart, caterina;
Jiménez, alfonso;
Manaca, maria nelia;
Aguilar, ruth;
Barbosa, arnoldo;
Rodríguez, mauricio H;
Cisteró, pau;
Quimice, lazaro M;
Menéndez, clara;
Aponte, john J;
Ordi, jaume;
Chitnis, chetan E;
Alonso, pedro L.
Background: Difficulties to disentangle the protective versus exposure role of anti-malarial antibodies hamper the identification of clinically-relevant immune targets. Here, factors affecting maternal IgG and IgMs against Plasmodium falciparum antigens, as well as their relationship with parasite infect...
Malaria, Falciparum/diagnosis,
Mozambique,
Plasmodium falciparum/immunology,
Antibodies, Monoclonal,
Immunoglobulin G/metabolism,
Population Characteristics,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/prevention & control,
Pregnancy Complications, Parasitic/diagnosis,
Pregnancy Complications, Parasitic/epidemiology,
Pregnancy Complications, Parasitic/prevention & control,
Pregnancy Complications, Parasitic/parasitology,
Prevalence
Valmaseda, aida;
Macete, eusebio;
Nhabomba, augusto;
Guinovart, caterina;
Aide, pedro;
Bardají, azucena;
Bassat, quique;
Nhampossa, tacilta;
Maculuve, sonia;
Casellas, aina;
Quintó, llorenç;
Sanz, sergi;
Jiménez, alfons;
Feng, gaoqian;
Langer, christine;
Reiling, linda;
Reddy, k, sony;
Pandey, alok;
Chitnis, chetan, e;
Chauhan, virander, s;
Aguilar, ruth;
Aponte, john, j;
Dobaño, carlota;
Beeson, james, g;
Gaur, deepak;
Menéndez, clara;
Alonso, pedro, l;
Mayor, alfredo.
Background: A main criterion to identify malaria vaccine candidates is the proof that acquired immunity against them is associated with protection from disease. The age of the studied individuals, heterogeneous malaria exposure, and assumption of the maintenance of a baseline immune response can confound...
Adaptive Immunity,
Age Factors,
Antibodies, Protozoan/immunology,
Antigens, Protozoan/immunology,
Immunoglobulin G/immunology,
Immunoglobulin M/immunology,
Malaria Vaccines/immunology,
Malaria, Falciparum/prevention & control,
Plasmodium falciparum,
Mozambique
