Compromise of Second-Line Antiretroviral Therapy Due to High Rates of Human Immunodeficiency Virus Drug Resistance in Mozambican Treatment-Experienced Children With Virologic Failure
Journal of the Pediatric Infectious Diseases Society; 9 (1), 2020
Background: Virologic failure (VF) is highly prevalent in sub-Saharan African children on antiretroviral therapy (ART) and is often associated with human immunodeficiency virus drug resistance (DR). Most children still lack access to routine viral load (VL) monitoring for early identification of treatmen...
Anti-Retroviral Agents/therapeutic use, Drug Resistance, Viral, HIV/radiation effects, HIV Infections/therapy, HIV Infections/virology, Lamivudine/therapeutic use, Lamivudine/pharmacology, Nevirapine/pharmacology, Nevirapine/therapeutic use, Stavudine/pharmacology, Stavudine/therapeutic use, Viral Load