Introdução: A malária é a principal causa de problemas de saúde em Moçambique, sendo responsável por cerca
de 40% de todas consultas externas nas unidades sanitárias do país. Este estudo visa analisar os processos de
crianças menores de 5 anos com diagnóstico de malária e convulsões, no dist...
Djimde, Moussa;
Tshiongo, Japhet Kabalu;
Muhindo, Hypolite Mavoko;
Tinto, Halidou;
Sevene, Esperança;
Traore, aminata;
Vala, Anifa;
Macuacua, Salesio;
Kabore, Berenger;
Dabira, Edgard Diniba;
Erhart, Annette;
Diakite, Hamadoun;
Keita, Mohamed;
Piqueras, Mireia;
González, Raquel;
Menendez, clara;
Dorlo, Thomas Pc;
Sagara, Issaka;
Mens, Petra;
Schallig, Henk;
D'Alessandro, Umberto;
Kayentao, Kassoum.
Malaria infection during pregnancy increases the risk of low birth weight and infant mortality and should be prevented and treated. Artemisinin-based combination treatments are generally well tolerated, safe and effective; the most used being artemether-lumefantrine (AL) and dihydroartemisinin-piperaquin...
Malaria, Falciparum/therapy,
Artemisinins/radiation effects,
Artemether, Lumefantrine Drug Combination,
Randomized Controlled Trials as Topic,
Pregnant Women,
Infection Control,
Parasitology,
Sub-Saharan African People,
Artemether/therapeutic use,
Antimalarials/radiation effects,
Mozambique/epidemiology
Xie, Kexi;
Marathe, Achla;
Deng, Xinwei;
Castillo, Paula Ruiz;
Imputiua, Saimado;
Elobolobo, Eldo;
Mutepa, Victor;
Sale 5, Mussa;
Nicolas, Patricia;
Montana, julia.
Background Residual malaria transmission is the result of adaptive mosquito behavior that allows malaria vectors to thrive and sustain transmission in the presence of good access to bed nets or insecticide residual spraying. These behaviors include crepuscular and outdoor feeding as well as intermittent ...
Mozambique/epidemiology,
Health Surveys,
Africa,
One Health,
Poverty,
Statistical Data,
Passive Cutaneous Anaphylaxis/drug effects,
Indicators and Reagents,
Surveys and Questionnaires/statistics & numerical data,
Malaria/drug therapy,
Malaria/prevention & control,
Malaria, Falciparum/complications
Background: Plasmodium falciparum infection in pregnant women in sub-Saharan Africa is often asymptomatic. As these forms of malaria are often submicroscopic and difficult to diagnose by conventional methods (microscopy and/or rapid diagnostic test), diagnosis requires the use of molecular techniques suc...
Silva , Clemente;
Boene, Simone;
Datta , Debayan;
Valbona, Eduard Rovira;
Díaz, Andrés Aranda 3 4;
Cisteró, Pau;
Hathaway , Nicholas;
Tessema, Sofonias;
Chidimatembue, Arlindo;
Matambisso, Glória;
Nhama, Abel;
Macete, Eusebio;
Pujol, Arnau;
Nhamussua , Lidia;
Galatas, Beatriz;
Guinovart, Caterina;
Enosse, Sónia;
Carvalho, Eva;
Rogier, Eric;
Plucinski, ateusz M;
Colborn, James;
Zulliger, Rose;
Saifodine, Abuchahama;
Alonso, Pedro L;
Candrinho , Baltazar;
Greenhouse , Bryan 3;
Saute, Francisco;
Mayor, Alfredo.
Mozambique is one of the four African countries which account for over half of all malaria deaths worldwide, yet little is known about the parasite genetic structure in that country. We performed P. falciparum amplicon and whole genome sequencing on 2251 malaria-infected blood samples collected in 2015 a...
Alafo, celso;
Malheia, arlindo;
Máquina, mara;
Soler, helena martí;
Aswat, ayesha S;
Koekemoer, lizette L;
Colborn, james;
Lobo, neil F;
Tatarski, allison;
Williams, yasmin A;
Marrenjo, dulcisária;
Cuamba, nelson;
Rabinovich, regina;
Alonso, Pedro;
Assessor, pedro;
Saute, francisco;
Paaijmans, krijn P.
Background: To eliminate malaria in southern Mozambique, the National Malaria Control Programme and its partners are scaling up indoor residual spraying (IRS) activities in two provinces, Gaza and Inhambane. An entomological surveillance planning tool (ESPT) was used to answer the programmatic question o...
Background: Malaria is still one of the leading causes of mortality and morbidity in Mozambique with little progress in malaria control over the past 20 years. Sussundenga is one of most affected areas. Malaria transmission has a strong association with environmental and sociodemographic factors. The kno...
Nhama , Abel;
Nhamússua, Lídia;
Macete, Eusébio;
Bassat, Quique;
Salvador, Crizolgo;
Enosse, Sónia;
Candrinho, Baltazar;
Carvalho, Eva;
Nhacolo, Arsénio;
Chidimatembue, Arlindo;
Saifodine , Abuchahama;
Zulliger, Rose;
Lucchi, Naomi;
Svigel, Samaly S;
Moriarty , Leah F;
Halsey, Eric S;
Mayor, Alfredo;
Aide , Pedro.
Artemisinin-based combination therapy (ACT) has been the recommended first-line treatment for uncomplicated malaria in Mozambique since 2006, with artemether-lumefantrine (AL) and amodiaquine-artesunate (AS-AQ) as the first choice. To assess efficacy of currently used ACT, an in vivo therapeutic efficacy...
Amodiaquine,
Antimalarials/therapeutic use,
Drug Combinations,
Antimalarials/standards,
Parasitemia,
Treatment Outcome,
d0082880,
Artemether, Lumefantrine Drug Combination/pharmacology,
Artemether, Lumefantrine Drug Combination/therapeutic use,
Malaria, Falciparum/therapy,
Parasitemia/drug therapy,
Mozambique/epidemiology
Smith, Alexandra Wharton;
Baker, Kevin;
Feltrer, Arantxa Roca;
Rodrigues, Maria;
Richardson, Sol;
Bonnington, Craig A;
Rassi, Christian;
Marasciulo, Madeleine;
Enosse, Sonia;
Saute, Francisco;
Aide, Pedro;
Macete, Eusebio;
Candrinho, Baltazar.
Background
Malaria is a significant cause of morbidity and mortality in children aged under 5 years in Mozambique. The World Health Organization recommends seasonal malaria chemoprevention (SMC), the administration of four monthly courses of sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ), to childre...
As malaria elimination becomes a possibility the focus of interventions changes from vector control to disease control. It is important that treatment occurs early during an infection in order for it to be efficacious, especially at the population level. The time between the onset of symptoms and treatme...