Alafo, celso;
Malheia, arlindo;
Máquina, mara;
Soler, helena martí;
Aswat, ayesha S;
Koekemoer, lizette L;
Colborn, james;
Lobo, neil F;
Tatarski, allison;
Williams, yasmin A;
Marrenjo, dulcisária;
Cuamba, nelson;
Rabinovich, regina;
Alonso, Pedro;
Assessor, pedro;
Saute, francisco;
Paaijmans, krijn P.
Background: To eliminate malaria in southern Mozambique, the National Malaria Control Programme and its partners are scaling up indoor residual spraying (IRS) activities in two provinces, Gaza and Inhambane. An entomological surveillance planning tool (ESPT) was used to answer the programmatic question o...
Background: Malaria is still one of the leading causes of mortality and morbidity in Mozambique with little progress in malaria control over the past 20 years. Sussundenga is one of most affected areas. Malaria transmission has a strong association with environmental and sociodemographic factors. The kno...
As malaria elimination becomes a possibility the focus of interventions changes from vector control to disease control. It is important that treatment occurs early during an infection in order for it to be efficacious, especially at the population level. The time between the onset of symptoms and treatme...
Chaccour, carlos;
Zulliger, rose;
Wagman, joe;
Casellas, aina;
Nacima, amilcar;
Elobolobo, eldo;
Savaio, binete;
Saifodine, abuchahama;
Fornadel, christen;
Richardson, jason;
Robertson, molly;
Saute, francisco.
Attaining the goal of reducing the global malaria burden is threatened by recent setbacks in maintaining the effectiveness of vector control interventions partly due to the emergence of pyrethroid resistant vectors. One potential strategy to address these setbacks could be combining indoor residual spray...
Infant,
Insecticide-Treated Bednets/statistics & numerical data,
Insecticides/administration & dosage,
Organothiophosphorus Compounds/administration & dosage,
Incidence,
Mosquito Control,
Malaria, Falciparum/epidemiology,
Mozambique/epidemiology,
Organothiophosphorus Compounds/supply & distribution,
Randomized Controlled Trials as Topic
Galatas, beatriz;
MontañàI, julia;
HamidoI, camilo;
Munguambe, humberto;
Wilson, Emily;
NhamussuaI, lidia;
GuinovartI, caterina;
SolerI, helena martı;
Saute, francisco;
Muguande, olinda3;
Maartens, francois4;
Luis, fabião;
Paaijmans, krijn;
Menéndez, clara;
Bassat, quique;
Mayor, alfredo;
Macete, eusebio;
Rabinovich, regina;
Alonso, pedro L;
Candrinho, baltazar;
Aide, pedro.
Background: Malaria eradication remains the long-term vision of the World Health Organization (WHO). However, whether malaria elimination is feasible in areas of stable transmission in sub-Saharan Africa with currently available tools remains a subject of debate. This study aimed to evaluate a multiphase...
Antimalarials/administration & dosage,
Infection Control/trends,
Infection Control/methods,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/prevention & control,
Malaria, Falciparum/transmission,
Mosquito Control/trends,
Mosquito Control/methods,
Mozambique
Galatas, beatriz;
Soler, helena martí;
Nhamussua, lidia;
Cisteró, pau;
Assessor, pedro;
Menéndez, clara;
Saute, francisco;
Rabinovich, regina;
Alonso, pedro L;
Prefeito, alfredo;
Bassat, quique.
Background. Afebrile Plasmodium falciparum infections usually remain undetected and untreated in the community and could potentially contribute to sustaining local malaria transmission in areas aiming for malaria elimination. Methods. Thirty-two men with afebrile P. falciparum infections detected with ra...
Mayor, alfredo;
Dobaño, carlota;
Nhabomba, augusto;
Guinovart, caterina;
Jiménez, alfonso;
Manaca, maria nelia;
Aguilar, ruth;
Barbosa, arnoldo;
Rodríguez, mauricio H;
Cisteró, pau;
Quimice, lazaro M;
Menéndez, clara;
Aponte, john J;
Ordi, jaume;
Chitnis, chetan E;
Alonso, pedro L.
Background: Difficulties to disentangle the protective versus exposure role of anti-malarial antibodies hamper the identification of clinically-relevant immune targets. Here, factors affecting maternal IgG and IgMs against Plasmodium falciparum antigens, as well as their relationship with parasite infect...
Malaria, Falciparum/diagnosis,
Mozambique,
Plasmodium falciparum/immunology,
Antibodies, Monoclonal,
Immunoglobulin G/metabolism,
Population Characteristics,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/prevention & control,
Pregnancy Complications, Parasitic/diagnosis,
Pregnancy Complications, Parasitic/epidemiology,
Pregnancy Complications, Parasitic/prevention & control,
Pregnancy Complications, Parasitic/parasitology,
Prevalence
Ndam, Nicaise Tuikue;
Mbuba, Emmanuel;
Gonzalez, Raquel 5;
Cistero, Pau;
Kariuki, Simon;
Sevene, Esperança;
Ruperez, María 5 6;
Fonseca, Ana Maria 5 9;
Vala, Anifa;
Muculuve, Sonia;
Jimenez, Alfons;
Quinto, Llorenç;
Ouma, Peter;
Ramharter, Michael;
Desai, Meghna;
Macete, Eusebio;
Cot, Michel;
Menendez, Clara;
Mayor, Alfredo.
Resistance and tolerance to Plasmodium falciparum can determine the progression of malaria disease. However, quantitative evidence of tolerance is still limited. We investigated variations in the adverse impact of P. falciparum infections among African pregnant women under different intensities of malari...
HIV Infections/complications,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/transmission,
Microscopy,
Placenta,
Plasmodium falciparum/immunology,
Pregnancy Complications, Infectious,
Pregnancy Outcome,
Real-Time Polymerase Chain Reaction
Salvador, Crizolgo;
Rafael, Bernardete;
Matsinhe, Francisco;
Matsinhe, Francisco;
Candrinho , Baltazar;
Muthemba , Rosália;
Carvalho, Eva;
Naueia, Eva;
Sacarlal, Jahit;
Namboze, Josephine;
Tiago , Armindo;
Warsame, Marian;
Enosse, Sónia.
he resistance of Plasmodium falciparum to anti-malarial drugs continues to challenge malaria control. We assessed the therapeutic efficacy and safety of artemether-lumefantrine (AL), the first-line treatment of uncomplicated P. falciparum malaria, in children under five years of age in Mozambique. We con...
Antimalarials/therapeutic use,
Artemisinins/therapeutic use,
Malaria/epidemiology,
d0109630,
d0200660,
d0161330,
Artemether, Lumefantrine Drug Combination,
Drug Combinations,
Ethanolamines/therapeutic use,
Fluorenes/therapeutic use,
Malaria, Falciparum/therapy,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/parasitology,
Plasmodium falciparum/genetics,
Polymerase Chain Reaction,
Mozambique/epidemiology
After the decrease in clinical malaria incidence observed in Mozambique until 2009, a steady resurgence of cases per year has been reported nationally, reaching alarming levels in 2014. However, little is known about the clinical profile of the cases presented, or the possible epidemiological factors con...
